KNAT KAPLAN NCLEX-RN PREP EXAM Infection Control
EXAM PREDICTION 2026 EDITION Q&A
1. A nurse is preparing to care for a patient with active
tuberculosis. Which type of isolation precaution is most
appropriate?
A. Droplet precautions
B. Contact precautions
C. Airborne precautions
D. Standard precautions only
Correct Answer: C
Explanation: Tuberculosis requires airborne precautions
because the bacteria are transmitted via small particles
that remain suspended in air. Droplet is for larger particles
(e.g., pertussis), contact for direct/indirect contact (e.g., C.
diff), and standard alone is insufficient for TB.
2. What is the MOST effective method to break the chain of
infection in a healthcare setting?
A. Educating patients about infections
B. Using personal protective equipment (PPE)
C. Implementing hand hygiene consistently
D. Scheduling staff vaccinations
Correct Answer: C
Explanation: Hand hygiene is the single most effective way
, to prevent transmission of pathogens. While PPE and
vaccinations are important, hand hygiene directly removes
pathogens and breaks the chain at the most common
transmission point.
3. A patient has Clostridioides difficile (C. diff) infection. Which
precaution should the nurse implement?
A. Airborne precautions
B. Droplet precautions
C. Contact precautions with gown and gloves
D. Standard precautions only
Correct Answer: C
Explanation: C. diff is transmitted via spores through direct
or indirect contact. Contact precautions including gown
and gloves are required. Airborne and droplet are not
needed since it's not respiratory.
4. When removing PPE, which item should be removed FIRST?
A. Gown
B. Goggles/Face shield
C. Gloves
D. Mask
Correct Answer: C
Explanation: Gloves are the most contaminated item and
should be removed first to prevent transferring pathogens
to other surfaces/body parts. The sequence is gloves →
gown/goggles → mask.
, 5. A nurse is caring for a patient with measles. Which
precaution is required?
A. Contact precautions
B. Airborne precautions
C. Droplet precautions
D. No special precautions needed
Correct Answer: B
Explanation: Measles is transmitted via airborne particles
and requires airborne precautions including a negative-
pressure room and N95 respirator. This is similar to
tuberculosis transmission.
6. Which hand hygiene method is appropriate when hands are
NOT visibly soiled?
A. Washing with water only
B. Using alcohol-based hand rub
C. Washing with soap and water for 10 seconds
D. Using antiseptic wipes only
Correct Answer: B
Explanation: Alcohol-based hand rubs are effective when
hands are not visibly soiled and are faster than washing.
Soap and water for at least 20 seconds is required when
hands are visibly dirty or for C. diff.
7. A patient is suspected of having pertussis (whooping cough).
Which precaution should be implemented?
A. Airborne precautions
B. Contact precautions
C. Droplet precautions
EXAM PREDICTION 2026 EDITION Q&A
1. A nurse is preparing to care for a patient with active
tuberculosis. Which type of isolation precaution is most
appropriate?
A. Droplet precautions
B. Contact precautions
C. Airborne precautions
D. Standard precautions only
Correct Answer: C
Explanation: Tuberculosis requires airborne precautions
because the bacteria are transmitted via small particles
that remain suspended in air. Droplet is for larger particles
(e.g., pertussis), contact for direct/indirect contact (e.g., C.
diff), and standard alone is insufficient for TB.
2. What is the MOST effective method to break the chain of
infection in a healthcare setting?
A. Educating patients about infections
B. Using personal protective equipment (PPE)
C. Implementing hand hygiene consistently
D. Scheduling staff vaccinations
Correct Answer: C
Explanation: Hand hygiene is the single most effective way
, to prevent transmission of pathogens. While PPE and
vaccinations are important, hand hygiene directly removes
pathogens and breaks the chain at the most common
transmission point.
3. A patient has Clostridioides difficile (C. diff) infection. Which
precaution should the nurse implement?
A. Airborne precautions
B. Droplet precautions
C. Contact precautions with gown and gloves
D. Standard precautions only
Correct Answer: C
Explanation: C. diff is transmitted via spores through direct
or indirect contact. Contact precautions including gown
and gloves are required. Airborne and droplet are not
needed since it's not respiratory.
4. When removing PPE, which item should be removed FIRST?
A. Gown
B. Goggles/Face shield
C. Gloves
D. Mask
Correct Answer: C
Explanation: Gloves are the most contaminated item and
should be removed first to prevent transferring pathogens
to other surfaces/body parts. The sequence is gloves →
gown/goggles → mask.
, 5. A nurse is caring for a patient with measles. Which
precaution is required?
A. Contact precautions
B. Airborne precautions
C. Droplet precautions
D. No special precautions needed
Correct Answer: B
Explanation: Measles is transmitted via airborne particles
and requires airborne precautions including a negative-
pressure room and N95 respirator. This is similar to
tuberculosis transmission.
6. Which hand hygiene method is appropriate when hands are
NOT visibly soiled?
A. Washing with water only
B. Using alcohol-based hand rub
C. Washing with soap and water for 10 seconds
D. Using antiseptic wipes only
Correct Answer: B
Explanation: Alcohol-based hand rubs are effective when
hands are not visibly soiled and are faster than washing.
Soap and water for at least 20 seconds is required when
hands are visibly dirty or for C. diff.
7. A patient is suspected of having pertussis (whooping cough).
Which precaution should be implemented?
A. Airborne precautions
B. Contact precautions
C. Droplet precautions
