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Question 1
Is the MMR vaccine live attenuated or inactivated?
Correct Answer:
Live attenuated
Rationalization:
Contains weakened viruses that replicate minimally → strong, lifelong immunity.
Avoid in:
• Pregnancy
• Immunocompromised patients
Question 2
Which of the following are live attenuated vaccines?
Correct Answer:
• MMR
• MMR-Varicella
, • Oral polio (OPV)
• Rotavirus
• Varicella
• Zoster (live version)
• Yellow fever
• Oral typhoid
• BCG
Critical Correction:
Cholera vaccine is NOT typically live attenuated in most exam contexts
Most commonly tested as inactivated (oral killed vaccine)
Question 3
Which vaccines are inactivated?
Correct Answer:
• DTaP
• Hib
• IPV (inactivated polio)
• Hep A & B
• HPV
• Pneumococcal
• Meningococcal
• Rabies
• Japanese encephalitis
• Plague
Exam Insight:
,If the patient is immunocompromised → choose inactivated vaccines
Question 4
What is the class and action of cefazolin?
Correct Answer:
1st-generation cephalosporin – bactericidal
Rationalization:
Kills bacteria by inhibiting cell wall synthesis
Question 5
What is the class and action of cefepime?
Correct Answer:
4th-generation cephalosporin – bactericidal
Question 6
What is the class and action of ciprofloxacin?
Correct Answer:
Fluoroquinolone – bactericidal
Rationalization:
Inhibits DNA gyrase → prevents replication.
Question 7
Macrolides (azithromycin, erythromycin) are bactericidal or bacteriostatic?
Correct Answer:
Bacteriostatic (usually)
Question 8
, What is unique about linezolid?
Correct Answer:
Bacteriostatic for most organisms but bactericidal against some streptococci
Question 9
What is doxycycline’s classification and action?
Correct Answer:
Tetracycline – bacteriostatic
Question 10
What is vancomycin’s classification and action?
Correct Answer:
Glycopeptide – bactericidal
Question 11
What is the difference between bactericidal and bacteriostatic drugs?
Correct Answer:
• Bactericidal: Kill bacteria directly
• Bacteriostatic: Inhibit growth → immune system clears infection
Clinical Insight:
Use bactericidal drugs for:
• Severe infections
• Immunocompromised patients
Question 12
What are the correct steps of ADME?
Correct Answer: