TEST BANK FOR TIETZ FUNDAMENTALS OF CLINICAL
CHEMISTRY AND MOLECULAR DIAGNOSTICS,
8TH EDITION BY NADER RIFAI, PHD
CHAPTERS 1 - 49
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
Table of contents:
I. Principles Of Laboratory Medicine
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
Chapter 3. Clinical Evaluation of Methods
Chapter 4. Evidence-Based Laboratory Medicine
Chapter 5. Establishment and Use of Reference Values
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
Chapter 7. Quality Management
II. Analytical Techniques And Instrumentation
Chapter 8. Principles of Basic Techniques and Laboratory Safety
Chapter 9. Optical Techniques
Chapter 10. Electrochemistry and Chemical Sensors
Chapter 11. Electrophoresis
Chapter 12. Chromatography
Chapter 13. Mass Spectrometry
Chapter 14. Enzyme and Rate Analyses
Chapter 15. Immunochemical Techniques
Chapter 16 Automation
Chapter 17. Point-of-Care Instrumentation
III. Analytes
Chapter 18. Amino Acids, Peptides, and Proteins
Chapter 19. Serum Enzymes
Chapter 20. Tumor Markers and Cancer Genes
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
Chapter 22. Carbohydrates
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
Chapter 24. Electrolytes and Blood Gases
Chapter 25. Hormones
Chapter 26. Catecholamines and Serotonin
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
Chapter 28. Hemoglobin, Iron, and Bilirubin
Chapter 29. Porphyrins and Porphyrias
Chapter 30. Therapeutic Drugs and Their Management
Chapter 31. Clinical Toxicology
Chapter 32. Toxic Metals
IV. Pathophysiology
Chapter 33. Diabetes
,Chapter 34. Cardiovascular Disease
Chapter 35. Kidney Disease
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
Chapter 37. Liver Disease
Chapter 38. Gastrointestinal and Pancreatic Diseases
Chapter 39. Disorders of Bone and Mineral Metabolism
Chapter 40. Disorders of the Pituitary Gland
Chapter 41. Disorders of the Adrenal Cortex
Chapter 42. Thyroid Disorders
Chapter 43. Reproduction-Related Disorders
Chapter 44. Pregnancy and Prenatal Testing
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
Chapter 46. Pharmacogenetics
V. Molecular Diagnostics
Chapter 47. Principles of Molecular Biology
Chapter 48. Nucleic Acid Techniques and Applications
Chapter 49. Genomes and Nucleic Acid Alterations
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine Test
xz xz xz xz xz xz xz xz xz xz
Bank
MULTIPLE CHOICE xz
1. An individual working in a clinical chemistry laboratory is married to a sales representative
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
who works for a company that sells chemistry laboratory supplies. When the laboratory man
xz xz xz xz xz xz xz xz xz xz xz xz xz
ager requests a list of needed supplies, cost of supplies, and vendors, this individual onlyreco
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
mmends the spouse’s company as the vendor. This is considered to be a(n):
xz xz xz xz xz xz xz xz xz xz xz xz
a. accounting issue. xz
b. possible conflict of interest. xz xz xz
c. maintenance of confidentiality issue. xz xz xz
d. problem with resource allocation. xz xz xz
ANS: B xz
Concern has been raised over the interrelationships between practitioners in the medical field
xz xz xz xz xz xz xz xz xz xz xz xz xz
and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
xz xz xz xz xz xz xz xz xz xz xz
Similarly, relationships have been scrutinized between clinical laboratorians and manufacturer
xz xz xz xz xz xz xz xz xz
s and providers of diagnostic equipment and supplies. These concerns led the National Institut
xz xz xz xz xz xz xz xz xz xz xz xz xz
es of Health (NIH) in 1995 to require official institutional review of financial disclosure by res
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
earchers and management of situations in which disclosure indicates potentialconflicts of inter
xz xz xz xz xz xz xz xz xz xz xz xz
est.
DIF: 1 REF: Page 4-5 xzxzxz xz OBJ: 6 | 7 xz xz xz
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce t
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
he pain following her recent surgery. A friend of the patient claims that the same painkiller“
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
worked wonders” to reduce her pain after the same surgery. The physician states that the dif
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
ference in the effect of the drug might be caused by
xz xz xz xz xz xz xz xz xz xz
, which is studied in pharmacogenetics.
xz xz xz xz xz
a. epidemiology
b. an inherited disease xz xz
c. a conflict of interest xz xz xz
d. a genetic variation in drug-metabolizing enzymes
xz xz xz xz xz
ANS: D xz
Pharmacogenetics is the study of the genetic variation of drug metabolism betweeni xz xz xz xz xz xz xz xz xz xz xz xz
ndividuals.
DIF: 1 REF: Page 3 xzxzx z xz OBJ: 1 xz
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the n
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
ame of a close friend printed on the bar-
xz xz xz xz xz xz xz xz
coded label. The genetic test that is ordered on thefriend’s sample would provide diagnostic
xz xz xz xz xz xz xz xz xz xz xz xz xz xz x
information about a disorder that has a poor prognosis, and the test is usually performed by
z xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz x
John. He asks a fellow employee to analyzethe sample for him and not divulge the results.
z xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
This ethical issue concerns:
xz xz xz
a. confidentiality of patient genetic and medical information. xz xz xz xz xz xz
b. a conflict of interest.xz xz xz
c. resource allocation. xz
d. diagnostic accuracy. xz
CHEMISTRY AND MOLECULAR DIAGNOSTICS,
8TH EDITION BY NADER RIFAI, PHD
CHAPTERS 1 - 49
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
Table of contents:
I. Principles Of Laboratory Medicine
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
Chapter 3. Clinical Evaluation of Methods
Chapter 4. Evidence-Based Laboratory Medicine
Chapter 5. Establishment and Use of Reference Values
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
Chapter 7. Quality Management
II. Analytical Techniques And Instrumentation
Chapter 8. Principles of Basic Techniques and Laboratory Safety
Chapter 9. Optical Techniques
Chapter 10. Electrochemistry and Chemical Sensors
Chapter 11. Electrophoresis
Chapter 12. Chromatography
Chapter 13. Mass Spectrometry
Chapter 14. Enzyme and Rate Analyses
Chapter 15. Immunochemical Techniques
Chapter 16 Automation
Chapter 17. Point-of-Care Instrumentation
III. Analytes
Chapter 18. Amino Acids, Peptides, and Proteins
Chapter 19. Serum Enzymes
Chapter 20. Tumor Markers and Cancer Genes
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
Chapter 22. Carbohydrates
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
Chapter 24. Electrolytes and Blood Gases
Chapter 25. Hormones
Chapter 26. Catecholamines and Serotonin
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
Chapter 28. Hemoglobin, Iron, and Bilirubin
Chapter 29. Porphyrins and Porphyrias
Chapter 30. Therapeutic Drugs and Their Management
Chapter 31. Clinical Toxicology
Chapter 32. Toxic Metals
IV. Pathophysiology
Chapter 33. Diabetes
,Chapter 34. Cardiovascular Disease
Chapter 35. Kidney Disease
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
Chapter 37. Liver Disease
Chapter 38. Gastrointestinal and Pancreatic Diseases
Chapter 39. Disorders of Bone and Mineral Metabolism
Chapter 40. Disorders of the Pituitary Gland
Chapter 41. Disorders of the Adrenal Cortex
Chapter 42. Thyroid Disorders
Chapter 43. Reproduction-Related Disorders
Chapter 44. Pregnancy and Prenatal Testing
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
Chapter 46. Pharmacogenetics
V. Molecular Diagnostics
Chapter 47. Principles of Molecular Biology
Chapter 48. Nucleic Acid Techniques and Applications
Chapter 49. Genomes and Nucleic Acid Alterations
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine Test
xz xz xz xz xz xz xz xz xz xz
Bank
MULTIPLE CHOICE xz
1. An individual working in a clinical chemistry laboratory is married to a sales representative
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
who works for a company that sells chemistry laboratory supplies. When the laboratory man
xz xz xz xz xz xz xz xz xz xz xz xz xz
ager requests a list of needed supplies, cost of supplies, and vendors, this individual onlyreco
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
mmends the spouse’s company as the vendor. This is considered to be a(n):
xz xz xz xz xz xz xz xz xz xz xz xz
a. accounting issue. xz
b. possible conflict of interest. xz xz xz
c. maintenance of confidentiality issue. xz xz xz
d. problem with resource allocation. xz xz xz
ANS: B xz
Concern has been raised over the interrelationships between practitioners in the medical field
xz xz xz xz xz xz xz xz xz xz xz xz xz
and commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
xz xz xz xz xz xz xz xz xz xz xz
Similarly, relationships have been scrutinized between clinical laboratorians and manufacturer
xz xz xz xz xz xz xz xz xz
s and providers of diagnostic equipment and supplies. These concerns led the National Institut
xz xz xz xz xz xz xz xz xz xz xz xz xz
es of Health (NIH) in 1995 to require official institutional review of financial disclosure by res
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
earchers and management of situations in which disclosure indicates potentialconflicts of inter
xz xz xz xz xz xz xz xz xz xz xz xz
est.
DIF: 1 REF: Page 4-5 xzxzxz xz OBJ: 6 | 7 xz xz xz
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce t
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
he pain following her recent surgery. A friend of the patient claims that the same painkiller“
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
worked wonders” to reduce her pain after the same surgery. The physician states that the dif
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
ference in the effect of the drug might be caused by
xz xz xz xz xz xz xz xz xz xz
, which is studied in pharmacogenetics.
xz xz xz xz xz
a. epidemiology
b. an inherited disease xz xz
c. a conflict of interest xz xz xz
d. a genetic variation in drug-metabolizing enzymes
xz xz xz xz xz
ANS: D xz
Pharmacogenetics is the study of the genetic variation of drug metabolism betweeni xz xz xz xz xz xz xz xz xz xz xz xz
ndividuals.
DIF: 1 REF: Page 3 xzxzx z xz OBJ: 1 xz
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the n
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
ame of a close friend printed on the bar-
xz xz xz xz xz xz xz xz
coded label. The genetic test that is ordered on thefriend’s sample would provide diagnostic
xz xz xz xz xz xz xz xz xz xz xz xz xz xz x
information about a disorder that has a poor prognosis, and the test is usually performed by
z xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz x
John. He asks a fellow employee to analyzethe sample for him and not divulge the results.
z xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
This ethical issue concerns:
xz xz xz
a. confidentiality of patient genetic and medical information. xz xz xz xz xz xz
b. a conflict of interest.xz xz xz
c. resource allocation. xz
d. diagnostic accuracy. xz
