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Axonal growth cones are highly dynamic structures that utilize
____________ to modulate formation of finger like extensions known
as filopodia and wave like extensions called _________
,A. Neurotrophins, microtubules
B. Apoptosis, dendritic spines
C. Bcl-2 family members, dendrites
D. Rho GTPase family members, lamellipodia - Answer: D
In an experiment involving an E10.5 mouse embryo, there is very little
Caspase-3 activation in the heterozygote. However, the homozygous
knockout mouse showed significant inrease in Caspase-3 labeling in the
developing DRG. Loss of which of the following genes would be LEAST
likely to result in this finding?
A. Bcl-2
B. NGF
C. Bax
D. TrkC
E. NT-3 - Answer: C
If you took a fibroblast and increased the expression of Oct4 (Pou5tf),
Myc, Klf4, and Sox2, you would be able to convert them into cells with
the differentiation potential most similar to which of the following?
A. Epiblast
,B. Satellite Cells
C. Neural Plate Cells
D. Somites
E. Zygote - Answer: A
What embryonic tissue generates most of the cells in the placenta that
regulate nutrient transfer between the maternal and fetal
bloodstreams?
A. Ectoderm
B. Endoderm
C. Mesoderm
D. Trophoblast - Answer: D
You have discovered that a pesticide binds to the androgen receptor
and causes defects in the developing male reproductive tract. This is an
example of which of the following?
A. Teratogen
B. Hormone
C. Endocrine disruptor
, D. Protein - Answer: C
If a woman has damaged Fallopian tubes, which of the following would
be the best protocol for in vitro fertilization?
A. Intra-Fallopian transfer of a fertilized oocyte
B. Intra-uterine transfer of a blastocyst
C. Intra-uterine transfer of a fertilized oocyte
D. Hormone replacement therapy - Answer: B
Where will neuroepithelial progenitors of the developing CNS undergo
mitosis?
A. at the ventricular surface
B. at the pial surface
C. at the midpoint halfway between the pia and ventricle
D. randomly at any point
E. neuroepithelial progenitors are postmitotic and do not divide -
Answer: A