ONS ONCC CHEMOTHERAPY IMMUNOTHERAPY
LATEST UPDATED ACTUAL QUESTIONS AND
ANSWERS SURE A+
✔✔Acute diarrhea lasts: - ✔✔1-2 days and resolves on its own
✔✔Persistent diarrhea lasts: - ✔✔2-4 weeks
✔✔Chronic diarrhea lasts: - ✔✔> 4 weeks
✔✔Common constipation-causing agents: - ✔✔Vinca alkaloids (vincristine and
vinorelbine)
Thalidomide
Lenalidomide
Bortezomib
✔✔mucositis - ✔✔Inflammation of the mucous membranes lining the digestive tract
from mouth to anus
✔✔stomatitis - ✔✔Inflammatory conditions of the mouth specifically
AKA oral mucositis
✔✔xerostomia - ✔✔Dryness of the mouth caused by damage to or dysfunction of the
salivary glands
✔✔Common diarrhea-causing agents: - ✔✔Irinotecan
5-FU
Paclitaxel
Dactinomycin
Capecitabine
, ✔✔Hypersensitivity reaction (HSR) versus anaphylaxis - ✔✔HSR- localized tissue
injury; generalized
Anaphylaxis- severe inflammatory response; systemic; caused by histamine release
✔✔Immediate HSR can occur: - ✔✔Within 5 minutes of start of infusion to 6 hours
following infusion
✔✔Delayed HSR can occur: - ✔✔Days or weeks after immediate HSR window
✔✔Risk factors for HSR and anaphylaxis: - ✔✔Administration of a known HSR causing
agent
Hx of allergies
Hx of hypersensitivity or anaphylaxis
Premedications not ordered/administered
✔✔First thing to do if a HSR occurs: - ✔✔STOP THE INFUSION IMMEDIATELY
✔✔Define course dose (AKA divided dose) - ✔✔Recommended dose of one
antineoplastic agent given over a defined period of time
✔✔Agents classified as irritants can cause: - ✔✔Inflammation
Pain
Burning
** Rarely cause tissue necrosis comparable to vesicants
✔✔Agents classified as vesicants can cause: - ✔✔Blistering
Significant pain
Tissue damage and destruction
**Lead to tissue death
✔✔Common plant alkaloids: - ✔✔Etoposide
Docetaxel
Paclitaxel
Vinblastine
Vinorelbine
✔✔Vinca alkaloids are ALL administered _(1)_ and should NEVER be administered
_(2)_, as this will result in patient death - ✔✔1. Intravenously
2. Intrathecally
✔✔How does hormone therapy work? - ✔✔Attempts to add, block, or remove hormones
from the body to interrupt cancer cell division
LATEST UPDATED ACTUAL QUESTIONS AND
ANSWERS SURE A+
✔✔Acute diarrhea lasts: - ✔✔1-2 days and resolves on its own
✔✔Persistent diarrhea lasts: - ✔✔2-4 weeks
✔✔Chronic diarrhea lasts: - ✔✔> 4 weeks
✔✔Common constipation-causing agents: - ✔✔Vinca alkaloids (vincristine and
vinorelbine)
Thalidomide
Lenalidomide
Bortezomib
✔✔mucositis - ✔✔Inflammation of the mucous membranes lining the digestive tract
from mouth to anus
✔✔stomatitis - ✔✔Inflammatory conditions of the mouth specifically
AKA oral mucositis
✔✔xerostomia - ✔✔Dryness of the mouth caused by damage to or dysfunction of the
salivary glands
✔✔Common diarrhea-causing agents: - ✔✔Irinotecan
5-FU
Paclitaxel
Dactinomycin
Capecitabine
, ✔✔Hypersensitivity reaction (HSR) versus anaphylaxis - ✔✔HSR- localized tissue
injury; generalized
Anaphylaxis- severe inflammatory response; systemic; caused by histamine release
✔✔Immediate HSR can occur: - ✔✔Within 5 minutes of start of infusion to 6 hours
following infusion
✔✔Delayed HSR can occur: - ✔✔Days or weeks after immediate HSR window
✔✔Risk factors for HSR and anaphylaxis: - ✔✔Administration of a known HSR causing
agent
Hx of allergies
Hx of hypersensitivity or anaphylaxis
Premedications not ordered/administered
✔✔First thing to do if a HSR occurs: - ✔✔STOP THE INFUSION IMMEDIATELY
✔✔Define course dose (AKA divided dose) - ✔✔Recommended dose of one
antineoplastic agent given over a defined period of time
✔✔Agents classified as irritants can cause: - ✔✔Inflammation
Pain
Burning
** Rarely cause tissue necrosis comparable to vesicants
✔✔Agents classified as vesicants can cause: - ✔✔Blistering
Significant pain
Tissue damage and destruction
**Lead to tissue death
✔✔Common plant alkaloids: - ✔✔Etoposide
Docetaxel
Paclitaxel
Vinblastine
Vinorelbine
✔✔Vinca alkaloids are ALL administered _(1)_ and should NEVER be administered
_(2)_, as this will result in patient death - ✔✔1. Intravenously
2. Intrathecally
✔✔How does hormone therapy work? - ✔✔Attempts to add, block, or remove hormones
from the body to interrupt cancer cell division
