FIRST AID FOR THE USMLE
COMPREHENSIVE TEST BANK COMPLETE
QUESTIONS AND VERIFIED SOLUTIONS
●● Abdominal pain, diarrhea, leukocytosis, recent antibiotic use
Answer: Clostridium difficile infection
●● Achilles tendon xanthoma
Answer: Familial hypercholesterolemia (decreased LDL receptor
signaling)
●● Adrenal hemorrhage, hypotension, DIC
Answer: Waterhouse-Friderichsen syndrome (menengococcemia)
●● Anaphylaxis following blood transfusion
Answer: IgA deficiency
●● Anterior "drawer sign" ⊕
Answer: Anterior cruciate ligament injury
●● Arachnodactyly, lens dislocation, aortic dissection, hyperflexible
joints
,Answer: Marfan syndrome (fibrillin defect)
●● Athlete with polycythemia
Answer: 2° to erythropoietin injection
●● Back pain, fever, night sweats
Answer: Pott disease (vertebral TB)
●● Bilateral acoustic schwannomas
Answer: Neurofibromatosis type 2
●● Bilateral hilar adenopathy, uveitis
Answer: Sarcoidosis (noncaseating granulomas)
●● Black eschar on face of patient with diabetic ketoacidosis
Answer: Mucor or Rhizopus fungal infection
●● Blue sclera, brittle bones
Answer: Osteogenesis imperfecta (type I collagen defect)
●● Bluish line on gingiva
Answer: Burton line (lead poisoning)
,●● Bone pain, bone enlargement, arthritis
Answer: Paget disease of bone (osteoblastic and osteoclastic activity)
●● Bounding pulses, diastolic heart murmur, head bobbing
Answer: Aortic regurgitation
●● "Butterfly" facial rash and Raynaud phenomenon in a young female
Answer: Systemic lupus erythematosus
●● Café-au-lait spots, Lisch nodules (iris hamartoma), cutaneous
neurofibromas, pheochromocytomas, optic gliomas A
nswer: Neurofibromatosis type I, pheochromocytoma, optic gliomas
●● Café-au-lait spots (unilateral), polyostotic fibrous dysplasia,
precocious puberty, multiple endocrine abnormalities A
nswer: McCune-Albright syndrome (mosaic G-protein signaling
mutation)
●● Calf pseudohypertrophy
Answer: Muscular dystrophy (most commonly Duchenne, due to X-
linked recessive frameshift mutation of dystrophin gene)
, ●● Child with cervical lymphadenopathy, desquamating rash, coronary
aneurysms, red conjunctivae and tongue
Answer: Kawasaki disease (treat with IVIG and aspirin)
●● "Cherry-red spots" on macula
Answer: Tay-Sachs (ganglioside accumulation) or Niemann-Pick
(sphingomyelin accumulation), central retinal artery occlusion
●● Chest pain on exertion
Answer: Angina (stable: with moderate exertion; unstable: with minimal
exertion or at rest)
●● Chest pain, pericardial effusion/friction rub, persistent fever
following MI
Answer: Dressler syndrome (autoimmune-mediated post-MI fibrinous
pericarditis, 2-12 weeks after acute episode
●● Chest pain with ST depressions on EKG
Answer: Unstable angina (troponins −) or NSTEMI (troponins +)
●● Child uses arms to stand up from squat
Answer: Gowers sign (Duchenne muscular dystrophy)
COMPREHENSIVE TEST BANK COMPLETE
QUESTIONS AND VERIFIED SOLUTIONS
●● Abdominal pain, diarrhea, leukocytosis, recent antibiotic use
Answer: Clostridium difficile infection
●● Achilles tendon xanthoma
Answer: Familial hypercholesterolemia (decreased LDL receptor
signaling)
●● Adrenal hemorrhage, hypotension, DIC
Answer: Waterhouse-Friderichsen syndrome (menengococcemia)
●● Anaphylaxis following blood transfusion
Answer: IgA deficiency
●● Anterior "drawer sign" ⊕
Answer: Anterior cruciate ligament injury
●● Arachnodactyly, lens dislocation, aortic dissection, hyperflexible
joints
,Answer: Marfan syndrome (fibrillin defect)
●● Athlete with polycythemia
Answer: 2° to erythropoietin injection
●● Back pain, fever, night sweats
Answer: Pott disease (vertebral TB)
●● Bilateral acoustic schwannomas
Answer: Neurofibromatosis type 2
●● Bilateral hilar adenopathy, uveitis
Answer: Sarcoidosis (noncaseating granulomas)
●● Black eschar on face of patient with diabetic ketoacidosis
Answer: Mucor or Rhizopus fungal infection
●● Blue sclera, brittle bones
Answer: Osteogenesis imperfecta (type I collagen defect)
●● Bluish line on gingiva
Answer: Burton line (lead poisoning)
,●● Bone pain, bone enlargement, arthritis
Answer: Paget disease of bone (osteoblastic and osteoclastic activity)
●● Bounding pulses, diastolic heart murmur, head bobbing
Answer: Aortic regurgitation
●● "Butterfly" facial rash and Raynaud phenomenon in a young female
Answer: Systemic lupus erythematosus
●● Café-au-lait spots, Lisch nodules (iris hamartoma), cutaneous
neurofibromas, pheochromocytomas, optic gliomas A
nswer: Neurofibromatosis type I, pheochromocytoma, optic gliomas
●● Café-au-lait spots (unilateral), polyostotic fibrous dysplasia,
precocious puberty, multiple endocrine abnormalities A
nswer: McCune-Albright syndrome (mosaic G-protein signaling
mutation)
●● Calf pseudohypertrophy
Answer: Muscular dystrophy (most commonly Duchenne, due to X-
linked recessive frameshift mutation of dystrophin gene)
, ●● Child with cervical lymphadenopathy, desquamating rash, coronary
aneurysms, red conjunctivae and tongue
Answer: Kawasaki disease (treat with IVIG and aspirin)
●● "Cherry-red spots" on macula
Answer: Tay-Sachs (ganglioside accumulation) or Niemann-Pick
(sphingomyelin accumulation), central retinal artery occlusion
●● Chest pain on exertion
Answer: Angina (stable: with moderate exertion; unstable: with minimal
exertion or at rest)
●● Chest pain, pericardial effusion/friction rub, persistent fever
following MI
Answer: Dressler syndrome (autoimmune-mediated post-MI fibrinous
pericarditis, 2-12 weeks after acute episode
●● Chest pain with ST depressions on EKG
Answer: Unstable angina (troponins −) or NSTEMI (troponins +)
●● Child uses arms to stand up from squat
Answer: Gowers sign (Duchenne muscular dystrophy)
