ASCP MLS UPDATED EXAMS SCRIPT ALL QUESTIONS
AND ANSWERS SURE A+
✔✔The prozone effect ( when performing a screening titer) is most likely to result in: -
✔✔Prozone effect (due to antibody excess) will result in an initial false negative in spite
of the large amount of antibody in the serum, followed by a positive result as the
specimen is diluted.
✔✔Which of the following Rh antigens is found the highest frequency in the Caucasian
population:
A. C
B. E
C. c
D. e - ✔✔D. e
✔✔The accuracy of an immunoassay is its ability to discriminate between results that
are true positives and results that are true negatives. Two parameters of test accuracy
are specificity and sensitivity. Which of these statements apply to an immunoassay with
high specificity, but low sensitivity? - ✔✔Accurately identifies the absence of disease
and has few false-positives
A test with high specificity accurately detects the absence of disease. The more specific
a test is, the fewer false-positive results will occur. A test with high sensitivity accurately
, identifies the presence of disease. The more sensitive a test, the fewer false-negative
results it produces. In the case stated in this question, the immunoassay has high
specificity, so it has few false-positives and will accurately detect those individuals who
do not have the disease or condition that is being tested for. However, the test has low
sensitivity, so it may not identify all individuals who actually have the disease; it may
produce many false-negative results.
✔✔Distinguishing characteristics of Micrococcus luteus: - ✔✔Resistance to furazolidone
is one of the key characteristics by which members of the genus Micrococcus (resistant)
can be separated from members of the genus Staphylococcus (susceptible).
Micrococcus species also are susceptible to novobiocin and to bacitracin, although the
zone of inhibition to the "A" disk is often small (as shown in this photograph).
✔✔The sickling phenomenon observed in erythrocytes containing hemoglobin S may be
induced by which of the following? - ✔✔Reducing agents actually induce the sickling
phenomenon in RBCs when they contain hemoglobin S.
✔✔If an autologous blood donor weighs 35 kg, how much blood can be collected for
later transfusion? - ✔✔315 mL
Volume to draw = (Donor's weight in kilograms / 50 kg (minimum weight requirement) x
450 mL (volume of unit to be donated)
In this case, Volume to draw = (35 kg / 50 kg) x 450 mL = 315 mL
✔✔Which adipokine is decreased in obesity, is anti-inflammatory, and increases insulin
sensitivity? - ✔✔Adiponectin is a protective cytokine. This cytokine is anti-inflammatory
and increases insulin sensitivity. Adiponectin is usually decreased in obesity.
✔✔Distinguishing characteristics of Mycobacterium fortuitum: - ✔✔Mycobacterium
fortuitum is positive for iron uptake, nitrate, arysulfatase, and growth on MacConkey
agar without crystal violet in five days.
✔✔CD5 antigen is normally found on which of the following lymphocyte populations? -
✔✔Mature T cells
✔✔Define: Congestive heart failure - ✔✔A left ventricular dysfunction resulting from
aging, hypertension, atherosclerosis or muscle damage from an AMI or repeated AMIs.
✔✔Define infarction: - ✔✔An area of tissue death that occurs due to lack of oxygen.
✔✔Define: Ischemia - ✔✔An inadequate blood supply that decreases availability of
oxygen.
AND ANSWERS SURE A+
✔✔The prozone effect ( when performing a screening titer) is most likely to result in: -
✔✔Prozone effect (due to antibody excess) will result in an initial false negative in spite
of the large amount of antibody in the serum, followed by a positive result as the
specimen is diluted.
✔✔Which of the following Rh antigens is found the highest frequency in the Caucasian
population:
A. C
B. E
C. c
D. e - ✔✔D. e
✔✔The accuracy of an immunoassay is its ability to discriminate between results that
are true positives and results that are true negatives. Two parameters of test accuracy
are specificity and sensitivity. Which of these statements apply to an immunoassay with
high specificity, but low sensitivity? - ✔✔Accurately identifies the absence of disease
and has few false-positives
A test with high specificity accurately detects the absence of disease. The more specific
a test is, the fewer false-positive results will occur. A test with high sensitivity accurately
, identifies the presence of disease. The more sensitive a test, the fewer false-negative
results it produces. In the case stated in this question, the immunoassay has high
specificity, so it has few false-positives and will accurately detect those individuals who
do not have the disease or condition that is being tested for. However, the test has low
sensitivity, so it may not identify all individuals who actually have the disease; it may
produce many false-negative results.
✔✔Distinguishing characteristics of Micrococcus luteus: - ✔✔Resistance to furazolidone
is one of the key characteristics by which members of the genus Micrococcus (resistant)
can be separated from members of the genus Staphylococcus (susceptible).
Micrococcus species also are susceptible to novobiocin and to bacitracin, although the
zone of inhibition to the "A" disk is often small (as shown in this photograph).
✔✔The sickling phenomenon observed in erythrocytes containing hemoglobin S may be
induced by which of the following? - ✔✔Reducing agents actually induce the sickling
phenomenon in RBCs when they contain hemoglobin S.
✔✔If an autologous blood donor weighs 35 kg, how much blood can be collected for
later transfusion? - ✔✔315 mL
Volume to draw = (Donor's weight in kilograms / 50 kg (minimum weight requirement) x
450 mL (volume of unit to be donated)
In this case, Volume to draw = (35 kg / 50 kg) x 450 mL = 315 mL
✔✔Which adipokine is decreased in obesity, is anti-inflammatory, and increases insulin
sensitivity? - ✔✔Adiponectin is a protective cytokine. This cytokine is anti-inflammatory
and increases insulin sensitivity. Adiponectin is usually decreased in obesity.
✔✔Distinguishing characteristics of Mycobacterium fortuitum: - ✔✔Mycobacterium
fortuitum is positive for iron uptake, nitrate, arysulfatase, and growth on MacConkey
agar without crystal violet in five days.
✔✔CD5 antigen is normally found on which of the following lymphocyte populations? -
✔✔Mature T cells
✔✔Define: Congestive heart failure - ✔✔A left ventricular dysfunction resulting from
aging, hypertension, atherosclerosis or muscle damage from an AMI or repeated AMIs.
✔✔Define infarction: - ✔✔An area of tissue death that occurs due to lack of oxygen.
✔✔Define: Ischemia - ✔✔An inadequate blood supply that decreases availability of
oxygen.
