ASCP MLS 2026 EXAMINERS SET QUESTIONS AND
ANSWERS SURE A+
✔✔Vitamin K Factors: - ✔✔factors II (prothrombin), VII, IX and X. Anticoagulation
proteins: proteins C, S
✔✔Christmas Disease: - ✔✔Deficiency in Factor IX
✔✔Amorphous urates is found in: - ✔✔Acidic pH urine
✔✔Amorphous phosphate crystals are found in: - ✔✔Amorphous phosphate, triple
phosphate (ammonium magnesium phosphate), calcium phosphate, and ammonium
urate crystals are frequently found in alkaline urine specimens
✔✔Which method is the gold standard for ANA detection: - ✔✔Slide-based
immunofluorescent assay (IFA) or colorzyme
✔✔NASBA - ✔✔Nucleic acid sequence based amplification (NASBA) is a method in
molecular biology which is used to amplify RNA sequences
Used to monitor viral load in HIV paitents
, ✔✔Which condition will show an increased PT with a normal aPTT? - ✔✔Factor VII
deficiency
✔✔A biomarker with high sensitivity: - ✔✔accurately identifies the presence of disease
and hos few false-negatives
✔✔A biomarker with a high specificity: - ✔✔accurately detects the absence of disease
and has few false-positives
✔✔Leukemoid Reaction Lab Results: - ✔✔A high white blood cell count, usually 50-100
x109/L with a left shift is a common finding in leukemoid reactions. In addition, a key
feature of a leukemoid reaction is a high LAP score
✔✔Low LAP score: - ✔✔Paroxysmal Nocturnal Hemoglobinuria, CML
✔✔Tay-Sachs Disease: - ✔✔A rare inherited disorder characterized by the near-total
deficiency of the enzyme N-acetylbetahexosaminidase A.
✔✔Term that means varying degree of leukocytosis with a shift to the left and
occasional nucleated red cell in the peripheral blood: - ✔✔Leukoerythroblastosis
✔✔Alder-Reilly inclusions: - ✔✔Mucopolysaccarids
✔✔Sodium nitroprusside on a urine reagent strip reacts with: - ✔✔Acetoacetic (diacetic)
acid- ketones
✔✔Glucose levels whole blood, serum and CSF: - ✔✔serum>whole blood>CSF
✔✔Increased numbers of basophils are often seen in: - ✔✔Chronic myelocytic leukemia
✔✔HLA antibodies are: - ✔✔HLA antibodies are formed in response to pregnancy,
transfusion or transplantation and are therefore not naturally occurring. They are
associated with febrile nonhemolytic transfusion reactions and TRALI. They are directed
against antigens found on granulocytes and other cells such as platelets.
✔✔Which of the following combinations is useful for confirming the presence of
extended spectrum beta-lactamases in E coli? - ✔✔Extended spectrum beta
lactamases (ESBL) are inhibited by clavulanic acid. Confirmatory tests of the presence
of ESBL are based on the enhanced activity of a beta-lactam antibiotic, usually
cefotaxime or ceftazidime, when it is tested with clavulanic acid compared to the activity
of the betalactam tested alone.
✔✔Low PCO2: - ✔✔Represents alkalosis
ANSWERS SURE A+
✔✔Vitamin K Factors: - ✔✔factors II (prothrombin), VII, IX and X. Anticoagulation
proteins: proteins C, S
✔✔Christmas Disease: - ✔✔Deficiency in Factor IX
✔✔Amorphous urates is found in: - ✔✔Acidic pH urine
✔✔Amorphous phosphate crystals are found in: - ✔✔Amorphous phosphate, triple
phosphate (ammonium magnesium phosphate), calcium phosphate, and ammonium
urate crystals are frequently found in alkaline urine specimens
✔✔Which method is the gold standard for ANA detection: - ✔✔Slide-based
immunofluorescent assay (IFA) or colorzyme
✔✔NASBA - ✔✔Nucleic acid sequence based amplification (NASBA) is a method in
molecular biology which is used to amplify RNA sequences
Used to monitor viral load in HIV paitents
, ✔✔Which condition will show an increased PT with a normal aPTT? - ✔✔Factor VII
deficiency
✔✔A biomarker with high sensitivity: - ✔✔accurately identifies the presence of disease
and hos few false-negatives
✔✔A biomarker with a high specificity: - ✔✔accurately detects the absence of disease
and has few false-positives
✔✔Leukemoid Reaction Lab Results: - ✔✔A high white blood cell count, usually 50-100
x109/L with a left shift is a common finding in leukemoid reactions. In addition, a key
feature of a leukemoid reaction is a high LAP score
✔✔Low LAP score: - ✔✔Paroxysmal Nocturnal Hemoglobinuria, CML
✔✔Tay-Sachs Disease: - ✔✔A rare inherited disorder characterized by the near-total
deficiency of the enzyme N-acetylbetahexosaminidase A.
✔✔Term that means varying degree of leukocytosis with a shift to the left and
occasional nucleated red cell in the peripheral blood: - ✔✔Leukoerythroblastosis
✔✔Alder-Reilly inclusions: - ✔✔Mucopolysaccarids
✔✔Sodium nitroprusside on a urine reagent strip reacts with: - ✔✔Acetoacetic (diacetic)
acid- ketones
✔✔Glucose levels whole blood, serum and CSF: - ✔✔serum>whole blood>CSF
✔✔Increased numbers of basophils are often seen in: - ✔✔Chronic myelocytic leukemia
✔✔HLA antibodies are: - ✔✔HLA antibodies are formed in response to pregnancy,
transfusion or transplantation and are therefore not naturally occurring. They are
associated with febrile nonhemolytic transfusion reactions and TRALI. They are directed
against antigens found on granulocytes and other cells such as platelets.
✔✔Which of the following combinations is useful for confirming the presence of
extended spectrum beta-lactamases in E coli? - ✔✔Extended spectrum beta
lactamases (ESBL) are inhibited by clavulanic acid. Confirmatory tests of the presence
of ESBL are based on the enhanced activity of a beta-lactam antibiotic, usually
cefotaxime or ceftazidime, when it is tested with clavulanic acid compared to the activity
of the betalactam tested alone.
✔✔Low PCO2: - ✔✔Represents alkalosis
