Nagelhout Pharm 2 Test 2 EXAM (2025) QUESTIONS AND (elaborated) WITH COMPLETE SOLUTIONS

Nagelhout Pharm 2 Test 2 EXAM (2025)
QUESTIONS AND (elaborated) WITH
COMPLETE SOLUTIONS

Enzymes for metabolism of catecholemines - ANSWER-COMT
MAO


Post synaptic neurotransmitter sympathetic - ANSWER-NE


Interference with synthesis of transmitter - ANSWER-sympatholytic - choline
acetyl transferase inhibitors


metabolic transformation by same pathway as precursor of transmitter - ANSWER-
sympatholytic - methyldopa


blockade of transport system at nerve terminal membrane - ANSWER-
sympathomimetic - cocaine


Blockade of transport system of storage vesicle - ANSWER-sympatholytic -
reserpine, vesamicol

, promotion of exocytosis or displacement of transmitter from axonal terminal -
ANSWER-sympathomimetic - amphetammine, tyramine


prevention of release of transmitter - ANSWER-sympatholytic - botulinim toxin,
clonidine, dexmedetomidine


mimicry of transmitter at postjunctional sites - ANSWER-sympathomimetic -
dobutamine, terbutaline, albuterol, isoproterenol, methacholine, bethanachol,
nicotine,


blockade of post synaptic receptor - ANSWER-sympatholytic - Atropine,
atracurium, -amines, -osin, -olol


inhibition of enzymatic breakdown of transmitter - ANSWER-sympathomimetic -
MAO inhibitors, COMT inhibitors, AChE inhibitors


interference with second messenger system - ANSWER-sympathomimetic -
milrinone


choline acetyl transferase inhibitors - ANSWER-sympatholytic


a-methyl tyrosine - ANSWER-sympatholytic


methyldopa - ANSWER-sympatholytic