NSG5240 MIDTERM EXAM REVIEW
QUESTIONS WITH 100% CORRECT
ANSWERS
\.Active transport - ANSWERS-Requires energy (ATP)
Moves low → high concentration
\.passive diffusion - ANSWERS-No energy required
Moves from high → low concentration
\.facilitated diffusion - ANSWERS-Uses carrier proteins
No energy required
\.What is drug absorption? - ANSWERS-The movement of a drug from
its site of administration into systemic circulation.
\.Where does oral drug absorption primarily occur? - ANSWERS-Small
intestine.
,\.What is the absorption phase for intravenous (IV) drug administration?
- ANSWERS-Immediate (no absorption phase).
\.Where does intramuscular (IM) or subcutaneous (SubQ) drug
absorption occur? - ANSWERS-Muscle or tissue.
\.Where does inhaled drug absorption occur? - ANSWERS-Lungs.
\.Factor affecting Drug Absorption - ANSWERS-Rate of dissolution
Surface area
Blood flow
Lipid Solubility
pH Partitioning
\.Excretion sites - ANSWERS-Renal (primary)
Non renal (breast milk, bile, lungs, sweat, and saliva)
\.Steps in Renal excretion - ANSWERS-Glomerular filtration
Passive tubular reabsorption
Active tubular reabsorption
\.Organs responsible for drug metabolism - ANSWERS-Main organ: Liver
, Others: kidneys, lungs, intestines
\.Therapeutic range - ANSWERS-plasma drug level between the
minimum effective concentration and toxic concentration
\.Agonists - ANSWERS-drugs that mimic body's own regulatory
molecules (Activates receptor)
\.Antagonists - ANSWERS-drugs that blocks actions of endogenous
regulators (Blocks receptor)
\.Partial agonist - ANSWERS-mimic actions of endogenous regulatory
molecules, but produces responses of intermediate intensity (Weak
activation)
\.Inhibitors - ANSWERS-Stops enzyme/process
\.Primary treatment of Asthma - ANSWERS-Rescue: Albuterol (SABA)
Control: Inhaled corticosteroids
\.Treatment of hypertension - ANSWERS-First-line:
ACE inhibitors (lisinopril)
QUESTIONS WITH 100% CORRECT
ANSWERS
\.Active transport - ANSWERS-Requires energy (ATP)
Moves low → high concentration
\.passive diffusion - ANSWERS-No energy required
Moves from high → low concentration
\.facilitated diffusion - ANSWERS-Uses carrier proteins
No energy required
\.What is drug absorption? - ANSWERS-The movement of a drug from
its site of administration into systemic circulation.
\.Where does oral drug absorption primarily occur? - ANSWERS-Small
intestine.
,\.What is the absorption phase for intravenous (IV) drug administration?
- ANSWERS-Immediate (no absorption phase).
\.Where does intramuscular (IM) or subcutaneous (SubQ) drug
absorption occur? - ANSWERS-Muscle or tissue.
\.Where does inhaled drug absorption occur? - ANSWERS-Lungs.
\.Factor affecting Drug Absorption - ANSWERS-Rate of dissolution
Surface area
Blood flow
Lipid Solubility
pH Partitioning
\.Excretion sites - ANSWERS-Renal (primary)
Non renal (breast milk, bile, lungs, sweat, and saliva)
\.Steps in Renal excretion - ANSWERS-Glomerular filtration
Passive tubular reabsorption
Active tubular reabsorption
\.Organs responsible for drug metabolism - ANSWERS-Main organ: Liver
, Others: kidneys, lungs, intestines
\.Therapeutic range - ANSWERS-plasma drug level between the
minimum effective concentration and toxic concentration
\.Agonists - ANSWERS-drugs that mimic body's own regulatory
molecules (Activates receptor)
\.Antagonists - ANSWERS-drugs that blocks actions of endogenous
regulators (Blocks receptor)
\.Partial agonist - ANSWERS-mimic actions of endogenous regulatory
molecules, but produces responses of intermediate intensity (Weak
activation)
\.Inhibitors - ANSWERS-Stops enzyme/process
\.Primary treatment of Asthma - ANSWERS-Rescue: Albuterol (SABA)
Control: Inhaled corticosteroids
\.Treatment of hypertension - ANSWERS-First-line:
ACE inhibitors (lisinopril)
