Clinical Genetics Review Exam I Questions With Complete
Solutions
A blunt ended arrow in a genetic or biochemical pathway
indicates Correct Answers enhancement of the reaction
a cross in which one parent is homozygous for the recessive
alleles of the genes under study and the other parent is ---or may
be---- heterozygous for these genes is called Correct Answers
test cross
a dominant mutation actually interefere with the function of the
wild-type allele by specifying polypeptides that inhibit,
anatognize, or limit the activity of the wildtype polypeptide
Correct Answers dominant-negative mutation
A graduate student treated some male fruit flies with gamma
rays and then mated them with normal females. In the progeny,
he found a male fly with a new phenotype. He mated the male
with 10 females who had known mutations. In the next
generation, all of the progeny looked wild type, except for the
progeny of female #6.
Did female #6 have a mutation in the same gene and the male
mutant? Correct Answers yes
A graduate student treated some male fruit flies with gamma
rays and then mated them with normal females. In the progeny,
he found a male fly with a new phenotype. He mated the male
with 10 females who had known mutations. In the next
, generation, all of the progeny looked wild type, except for the
progeny of female #6.
What is the name of this type of analysis? Correct Answers
complementation
A marriage between relatives. This mating is more likely to
produce individuals who are doubly recessive for mutations.
Correct Answers consanguineous mating
a mating between relatives is often referred to as Correct
Answers consanguineous mating
A multigenerational map to explore the inheritance pattern of a
mutation. Correct Answers pedigree
a mutant allele is created when an existing allele changes to a
new genetic state Correct Answers mutation
a mutant allele of a gene that interferes with the function of the
wild type allele so that individuals who are heterozygous for the
mutation and the wild type have the mutant phenotype Correct
Answers dominant negative
A mutation in the Lozenge gene will cause fruit flies to be
sterile, blind and have no claws. What term describes a mutation
that has multiple phenotypic effects? Correct Answers
pleiotrophic
A mutation that has less expression than wild type, but still
produces a product. Correct Answers complementation
Solutions
A blunt ended arrow in a genetic or biochemical pathway
indicates Correct Answers enhancement of the reaction
a cross in which one parent is homozygous for the recessive
alleles of the genes under study and the other parent is ---or may
be---- heterozygous for these genes is called Correct Answers
test cross
a dominant mutation actually interefere with the function of the
wild-type allele by specifying polypeptides that inhibit,
anatognize, or limit the activity of the wildtype polypeptide
Correct Answers dominant-negative mutation
A graduate student treated some male fruit flies with gamma
rays and then mated them with normal females. In the progeny,
he found a male fly with a new phenotype. He mated the male
with 10 females who had known mutations. In the next
generation, all of the progeny looked wild type, except for the
progeny of female #6.
Did female #6 have a mutation in the same gene and the male
mutant? Correct Answers yes
A graduate student treated some male fruit flies with gamma
rays and then mated them with normal females. In the progeny,
he found a male fly with a new phenotype. He mated the male
with 10 females who had known mutations. In the next
, generation, all of the progeny looked wild type, except for the
progeny of female #6.
What is the name of this type of analysis? Correct Answers
complementation
A marriage between relatives. This mating is more likely to
produce individuals who are doubly recessive for mutations.
Correct Answers consanguineous mating
a mating between relatives is often referred to as Correct
Answers consanguineous mating
A multigenerational map to explore the inheritance pattern of a
mutation. Correct Answers pedigree
a mutant allele is created when an existing allele changes to a
new genetic state Correct Answers mutation
a mutant allele of a gene that interferes with the function of the
wild type allele so that individuals who are heterozygous for the
mutation and the wild type have the mutant phenotype Correct
Answers dominant negative
A mutation in the Lozenge gene will cause fruit flies to be
sterile, blind and have no claws. What term describes a mutation
that has multiple phenotypic effects? Correct Answers
pleiotrophic
A mutation that has less expression than wild type, but still
produces a product. Correct Answers complementation
