Gene interaction Exam Questions With Complete Solutions
Example of a dominant lethal allele Correct Answers
Huntington's disease
Example of recessive lethal allele Correct Answers Cystic
fibrosis, achondroplasia, Sickle cell anaemia
How can you find out the variations of dominance? Correct
Answers If dominance and recessive is not known, you can
cross with each other starting with pure breeders to see how
certain alleles are expressed in a heterozygote
How do suppressors work? Correct Answers At first the
mutation alters the binding site of one protein so that it can no
longer bind to a partner a suppressor mutation, and the partner
alters the binding site so that both proteins are able to bind once
again so two mutations allow it to function normally
How do you decide whether two mutations belong to the same
gene? Correct Answers Complementation test
How do you produce a complementation test? Correct Answers
1) intercross, two individuals homozygous for recessive
mutation
2) if progeny shows the wild type phenotype, the two recessive
mutations must be different genes
3) if progeny does not have wild type, phenotype shows the
mutant phenotype do not complement and are on the same gene
, How is a double mutant obtained Correct Answers Crossing
two single mutants and selfing F1
How is it evident that gene are interacting? Correct Answers
Modified ratios in F2 where there is a range of modified 9331
ratios
How is sickle cell trait a form of co-dominance? Correct
Answers When a heterozygous sickle cell trait is analyzed
under electrophoresis, it is shown that both heterozygotes can
express the protein product of both alleles
How to identify gene fractions in haploid Correct Answers You
would form the two mutant haploids into a diploid and force it
through meiosis if both are present, there's no gene interaction.
If only one phenotype is shown then epistasis is present due to
the masking of one phenotype if it is dead, that's an example of
synthetic lethal and if the genotype is well type, it is suppression
How was the interaction of genes and pathways discovered
Correct Answers Biosynthetic pathways were discovered by
George and Edward through the metabolism of Neurospora
fungus
What are different types of lethal alleles? Correct Answers
Recessive lethall
Dominant lethal
Conditional lethal
What are examples of co dominance ? Correct Answers An
example would be the blood types
Example of a dominant lethal allele Correct Answers
Huntington's disease
Example of recessive lethal allele Correct Answers Cystic
fibrosis, achondroplasia, Sickle cell anaemia
How can you find out the variations of dominance? Correct
Answers If dominance and recessive is not known, you can
cross with each other starting with pure breeders to see how
certain alleles are expressed in a heterozygote
How do suppressors work? Correct Answers At first the
mutation alters the binding site of one protein so that it can no
longer bind to a partner a suppressor mutation, and the partner
alters the binding site so that both proteins are able to bind once
again so two mutations allow it to function normally
How do you decide whether two mutations belong to the same
gene? Correct Answers Complementation test
How do you produce a complementation test? Correct Answers
1) intercross, two individuals homozygous for recessive
mutation
2) if progeny shows the wild type phenotype, the two recessive
mutations must be different genes
3) if progeny does not have wild type, phenotype shows the
mutant phenotype do not complement and are on the same gene
, How is a double mutant obtained Correct Answers Crossing
two single mutants and selfing F1
How is it evident that gene are interacting? Correct Answers
Modified ratios in F2 where there is a range of modified 9331
ratios
How is sickle cell trait a form of co-dominance? Correct
Answers When a heterozygous sickle cell trait is analyzed
under electrophoresis, it is shown that both heterozygotes can
express the protein product of both alleles
How to identify gene fractions in haploid Correct Answers You
would form the two mutant haploids into a diploid and force it
through meiosis if both are present, there's no gene interaction.
If only one phenotype is shown then epistasis is present due to
the masking of one phenotype if it is dead, that's an example of
synthetic lethal and if the genotype is well type, it is suppression
How was the interaction of genes and pathways discovered
Correct Answers Biosynthetic pathways were discovered by
George and Edward through the metabolism of Neurospora
fungus
What are different types of lethal alleles? Correct Answers
Recessive lethall
Dominant lethal
Conditional lethal
What are examples of co dominance ? Correct Answers An
example would be the blood types
