ADVANCED CARDIOVASCULAR LIFE SUPPORT (ACLS) EXAM PREDICTION WITH QUESTIONS AND CORRECT ANSWERS 2026

ADVANCED CARDIOVASCULAR LIFE SUPPORT (ACLS) EXAM
PREDICTION WITH QUESTIONS AND CORRECT ANSWERS 2026
During cardiac arrest resuscitation, which compression-to-ventilation
ratio should be used when no advanced airway is in place?
A. 15:2
B. 30:2
C. 5:1
D. 10:2
Correct Answer: B
Explanation: The 2025 AHA guidelines specify a 30:2 compression-to-
ventilation ratio for adult cardiac arrest when no advanced airway is in
place. This ratio optimizes perfusion while providing adequate
ventilation.


What is the recommended depth for high-quality chest compressions in
adult cardiac arrest?
A. At least 1.5 inches (3.8 cm)
B. At least 2 inches (5 cm) but not more than 2.4 inches (6 cm)
C. At least 2.5 inches (6.3 cm)
D. Exactly 3 inches (7.6 cm)
Correct Answer: B
Explanation: The 2025 guidelines recommend compressing at least 2
inches (5 cm) but not more than 2.4 inches (6 cm) to ensure adequate
perfusion while avoiding injury.

,Which medication is the first-line drug for symptomatic bradycardia in
the ACLS algorithm?
A. Epinephrine
B. Dopamine
C. Atropine
D. Amiodarone
Correct Answer: C
Explanation: Atropine remains the first-line drug for symptomatic
bradycardia at 1 mg IV bolus, repeated every 3-5 minutes to a
maximum of 3 mg total dose.


What is the initial epinephrine dose for adult cardiac arrest during ACLS
resuscitation?
A. 0.5 mg IV/IO every 3-5 minutes
B. 1 mg IV/IO every 3-5 minutes
C. 2 mg IV/IO every 3-5 minutes
D. 1 mg IV/IO every 1-2 minutes
Correct Answer: B
Explanation: The standard epinephrine dose for cardiac arrest is 1 mg
IV/IO every 3-5 minutes according to 2025 AHA guidelines.


For shockable rhythms (VF/pVT), what is the recommended initial
biphasic defibrillation energy dose?
A. 50-100 J
B. 120-200 J (manufacturer recommendation)
C. 300 J
D. 360 J

,Correct Answer: B
Explanation: The 2025 guidelines recommend initial biphasic shock
energy of 120-200 J based on manufacturer recommendation; if
unknown, use maximum available.


What is the first dose of amiodarone for refractory ventricular
fibrillation during cardiac arrest?
A. 150 mg IV/IO bolus
B. 300 mg IV/IO bolus
C. 450 mg IV/IO bolus
D. 5 mg/kg IV/IO bolus
Correct Answer: B
Explanation: The first dose of amiodarone for VF/pVT is 300 mg IV/IO
bolus, followed by a second dose of 150 mg if needed.


Which of the following is NOT one of the 6 H's (reversible causes) in
ACLS?
A. Hypovolemia
B. Hypertension
C. Hypoxia
D. Hyperkalemia/Hypokalemia
Correct Answer: B
Explanation: Hypertension is not one of the H's. The 6 H's are:
Hypovolemia, Hypoxia, Hydrogen ion (acidosis), Hyper-/hypokalemia,
Hypoglycemia, and Hypothermia.

, After an advanced airway is placed during cardiac arrest, what is the
recommended ventilation rate?
A. 1 breath every 3 seconds (20 breaths/min)
B. 1 breath every 6 seconds (10 breaths/min)
C. 1 breath every 10 seconds (6 breaths/min)
D. 15 breaths per minute
Correct Answer: B
Explanation: With an advanced airway in place, give 1 breath every 6
seconds (10 breaths/min) with continuous chest compressions.


Which of the following is one of the 5 T's (reversible causes) in ACLS?
A. Trauma
B. Tension pneumothorax
C. Thrombocytopenia
D. Toxicology screening
Correct Answer: B
Explanation: Tension pneumothorax is one of the 5 T's. The complete list
includes: Tension pneumothorax, Tamponade (cardiac), Toxins,
Thrombosis (pulmonary), and Thrombosis (coronary).


What is the recommended compression rate for high-quality CPR in
adult cardiac arrest?
A. 80-100/min
B. 100-120/min
C. 120-140/min
D. 90-110/min
Correct Answer: B