COMSAE Phase 2 Form 111 Exam
Practice Questions And Correct Answers
(Verified Answers) Plus Rationales 2026
Q&A | Instant Download Pdf
1. A 62-year-old man with long-standing hypertension presents with
sudden onset chest pain radiating to the back. Blood pressure is
190/110 mmHg in the right arm and 160/90 mmHg in the left arm.
Which is the most likely diagnosis?
A. Myocardial infarction
B. Pulmonary embolism
C. Aortic dissection
D. Pericarditis
C. Aortic dissection
The combination of tearing chest pain radiating to the back and
unequal blood pressures between arms strongly suggests aortic
dissection involving branch vessels.
2. A 45-year-old woman presents with fatigue, weight gain, and cold
intolerance. Labs show elevated TSH and low free T4. What is the
, diagnosis?
A. Graves disease
B. Hashimoto thyroiditis
C. Subacute thyroiditis
D. Pituitary adenoma
B. Hashimoto thyroiditis
Primary hypothyroidism with elevated TSH and low T4 is most
commonly due to autoimmune Hashimoto thyroiditis.
3. A 30-year-old man presents with fever, night sweats, and painless
lymphadenopathy. Reed-Sternberg cells are seen on biopsy.
Diagnosis?
A. Non-Hodgkin lymphoma
B. Hodgkin lymphoma
C. Tuberculosis
D. Sarcoidosis
B. Hodgkin lymphoma
Reed-Sternberg cells are pathognomonic for Hodgkin lymphoma.
4. A diabetic patient presents with fruity breath odor and Kussmaul
respirations. Which acid-base disorder is expected?
A. Respiratory acidosis
B. Metabolic alkalosis
C. Metabolic acidosis with anion gap
D. Respiratory alkalosis
, C. Metabolic acidosis with anion gap
Diabetic ketoacidosis produces ketone accumulation causing high
anion gap metabolic acidosis.
5. A child presents with barking cough and inspiratory stridor. Diagnosis?
A. Epiglottitis
B. Asthma
C. Croup
D. Bronchiolitis
C. Croup
Parainfluenza virus causes croup, characterized by barking cough and
stridor.
6. A 70-year-old man has tremor at rest, rigidity, and bradykinesia. Which
structure is affected?
A. Cerebellum
B. Substantia nigra
C. Hippocampus
D. Thalamus
B. Substantia nigra
Parkinson disease is caused by degeneration of dopaminergic
neurons in the substantia nigra.
7. A patient has severe right upper quadrant pain after fatty meals.
Ultrasound shows gallstones. What hormone triggers gallbladder
contraction?
, A. Secretin
B. Cholecystokinin
C. Gastrin
D. Somatostatin
B. Cholecystokinin
CCK stimulates gallbladder contraction and pancreatic enzyme
secretion.
8. A woman presents with exophthalmos and heat intolerance. Lab
shows low TSH and high T4. Diagnosis?
A. Hashimoto thyroiditis
B. Graves disease
C. Thyroid cancer
D. Hypothyroidism
B. Graves disease
Graves disease is an autoimmune hyperthyroidism causing
ophthalmopathy and low TSH.
9. A patient presents with hemoptysis and cavitary lung lesions. Acid-fast
bacilli are seen. Diagnosis?
A. Pneumonia
B. Tuberculosis
C. Lung cancer
D. Sarcoidosis
Practice Questions And Correct Answers
(Verified Answers) Plus Rationales 2026
Q&A | Instant Download Pdf
1. A 62-year-old man with long-standing hypertension presents with
sudden onset chest pain radiating to the back. Blood pressure is
190/110 mmHg in the right arm and 160/90 mmHg in the left arm.
Which is the most likely diagnosis?
A. Myocardial infarction
B. Pulmonary embolism
C. Aortic dissection
D. Pericarditis
C. Aortic dissection
The combination of tearing chest pain radiating to the back and
unequal blood pressures between arms strongly suggests aortic
dissection involving branch vessels.
2. A 45-year-old woman presents with fatigue, weight gain, and cold
intolerance. Labs show elevated TSH and low free T4. What is the
, diagnosis?
A. Graves disease
B. Hashimoto thyroiditis
C. Subacute thyroiditis
D. Pituitary adenoma
B. Hashimoto thyroiditis
Primary hypothyroidism with elevated TSH and low T4 is most
commonly due to autoimmune Hashimoto thyroiditis.
3. A 30-year-old man presents with fever, night sweats, and painless
lymphadenopathy. Reed-Sternberg cells are seen on biopsy.
Diagnosis?
A. Non-Hodgkin lymphoma
B. Hodgkin lymphoma
C. Tuberculosis
D. Sarcoidosis
B. Hodgkin lymphoma
Reed-Sternberg cells are pathognomonic for Hodgkin lymphoma.
4. A diabetic patient presents with fruity breath odor and Kussmaul
respirations. Which acid-base disorder is expected?
A. Respiratory acidosis
B. Metabolic alkalosis
C. Metabolic acidosis with anion gap
D. Respiratory alkalosis
, C. Metabolic acidosis with anion gap
Diabetic ketoacidosis produces ketone accumulation causing high
anion gap metabolic acidosis.
5. A child presents with barking cough and inspiratory stridor. Diagnosis?
A. Epiglottitis
B. Asthma
C. Croup
D. Bronchiolitis
C. Croup
Parainfluenza virus causes croup, characterized by barking cough and
stridor.
6. A 70-year-old man has tremor at rest, rigidity, and bradykinesia. Which
structure is affected?
A. Cerebellum
B. Substantia nigra
C. Hippocampus
D. Thalamus
B. Substantia nigra
Parkinson disease is caused by degeneration of dopaminergic
neurons in the substantia nigra.
7. A patient has severe right upper quadrant pain after fatty meals.
Ultrasound shows gallstones. What hormone triggers gallbladder
contraction?
, A. Secretin
B. Cholecystokinin
C. Gastrin
D. Somatostatin
B. Cholecystokinin
CCK stimulates gallbladder contraction and pancreatic enzyme
secretion.
8. A woman presents with exophthalmos and heat intolerance. Lab
shows low TSH and high T4. Diagnosis?
A. Hashimoto thyroiditis
B. Graves disease
C. Thyroid cancer
D. Hypothyroidism
B. Graves disease
Graves disease is an autoimmune hyperthyroidism causing
ophthalmopathy and low TSH.
9. A patient presents with hemoptysis and cavitary lung lesions. Acid-fast
bacilli are seen. Diagnosis?
A. Pneumonia
B. Tuberculosis
C. Lung cancer
D. Sarcoidosis
