20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx
Oxford Cambridge and RSA
Monday 9 June 2025 – Morning
GCSE (9–1) Combined Science A
(Gateway Science)
J250/02 Biology (Foundation Tier)
Time allowed: 1 hour 10 minutes
F
*1860972117*
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
* J 2 5 0 0 2 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/8687/2] OCR is an exempt Charity
DC (IP/SG) 353356/5 Turn over
20251202204138_692f4f024ffda_ngcr__40_.docx 1 20251202204138_692f4f024ffda_ngcr__40_.docx
,20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx
2
Section A
You should spend a maximum of 20 minutes on this section.
Write your answer to each question in the box provided.
1 The diagram shows a key for identifying organisms.
Identify the organism that has wings and is active at night.
Has the organism got legs?
Yes No
Has it got wings? Has it got a shell?
No Yes No Yes
Has it got more Is it active at night?
than eight legs?
Yes No Yes No Worm Snail
Centipede Spider Moth Butterfly
A Butterfly
B Centipede
C Moth
D Snail
Your answer [1]
© OCR 2025
20251202204138_692f4f024ffda_ngcr__40_.docx 2 20251202204138_692f4f024ffda_ngcr__40_.docx
,20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx
3
2 What is the correct treatment for a disease caused by viruses?
A Antibiotics
B Antivirals
C Progesterone
D Insulin
Your answer [1]
3 Which of these is an example of genetic engineering?
A Captive breeding programmes for endangered species
B Farmers applying pesticides on their crops
C Scientists developing crops that are drought resistant
D Selecting pigs with high quality meat to breed together
Your answer [1]
4 Cardiovascular diseases are treated in different ways.
The table shows some treatments for cardiovascular disease.
Treatment Description
A Heart bypass A new blood vessel is inserted when the coronary artery is blocked.
B Heart transplant A new heart from a donor is inserted.
C Statins A pill is ingested which reduces cholesterol in the blood.
D Stent A small tube is inserted to open up a blocked blood vessel.
Which treatment does not involve surgery?
Your answer [1]
© OCR 2025 Turn over
20251202204138_692f4f024ffda_ngcr__40_.docx 3 20251202204138_692f4f024ffda_ngcr__40_.docx
, 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx
4
5 Which of these could be used to group living organisms in a natural classification system?
A DNA sequence
B Number of legs
C Presence of shell
D Size of tail
Your answer [1]
6 Which of these is a non-specific defence mechanism of the human body against pathogens?
A Making red blood cells
B Pancreas producing insulin
C Pupil changing size
D Stomach producing acid
Your answer [1]
7 Scientists have developed a detailed understanding of the human genome.
Which of these is a benefit from developing this understanding?
A Discovering new antibiotics
B Explaining why antibiotic resistant bacteria have evolved
C Predicting whether a person will develop a genetic condition
D Using embryonic stem cells for transplants
Your answer [1]
© OCR 2025
20251202204138_692f4f024ffda_ngcr__40_.docx 4 20251202204138_692f4f024ffda_ngcr__40_.docx
Oxford Cambridge and RSA
Monday 9 June 2025 – Morning
GCSE (9–1) Combined Science A
(Gateway Science)
J250/02 Biology (Foundation Tier)
Time allowed: 1 hour 10 minutes
F
*1860972117*
You must have:
• a ruler (cm/mm)
You can use:
• a scientific or graphical calculator
• an HB pencil
* J 2 5 0 0 2 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 60.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 24 pages.
ADVICE
• Read each question carefully before you start your answer.
© OCR 2025 [601/8687/2] OCR is an exempt Charity
DC (IP/SG) 353356/5 Turn over
20251202204138_692f4f024ffda_ngcr__40_.docx 1 20251202204138_692f4f024ffda_ngcr__40_.docx
,20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx
2
Section A
You should spend a maximum of 20 minutes on this section.
Write your answer to each question in the box provided.
1 The diagram shows a key for identifying organisms.
Identify the organism that has wings and is active at night.
Has the organism got legs?
Yes No
Has it got wings? Has it got a shell?
No Yes No Yes
Has it got more Is it active at night?
than eight legs?
Yes No Yes No Worm Snail
Centipede Spider Moth Butterfly
A Butterfly
B Centipede
C Moth
D Snail
Your answer [1]
© OCR 2025
20251202204138_692f4f024ffda_ngcr__40_.docx 2 20251202204138_692f4f024ffda_ngcr__40_.docx
,20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx
3
2 What is the correct treatment for a disease caused by viruses?
A Antibiotics
B Antivirals
C Progesterone
D Insulin
Your answer [1]
3 Which of these is an example of genetic engineering?
A Captive breeding programmes for endangered species
B Farmers applying pesticides on their crops
C Scientists developing crops that are drought resistant
D Selecting pigs with high quality meat to breed together
Your answer [1]
4 Cardiovascular diseases are treated in different ways.
The table shows some treatments for cardiovascular disease.
Treatment Description
A Heart bypass A new blood vessel is inserted when the coronary artery is blocked.
B Heart transplant A new heart from a donor is inserted.
C Statins A pill is ingested which reduces cholesterol in the blood.
D Stent A small tube is inserted to open up a blocked blood vessel.
Which treatment does not involve surgery?
Your answer [1]
© OCR 2025 Turn over
20251202204138_692f4f024ffda_ngcr__40_.docx 3 20251202204138_692f4f024ffda_ngcr__40_.docx
, 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx 20251202204138_692f4f024ffda_ngcr__40_.docx
4
5 Which of these could be used to group living organisms in a natural classification system?
A DNA sequence
B Number of legs
C Presence of shell
D Size of tail
Your answer [1]
6 Which of these is a non-specific defence mechanism of the human body against pathogens?
A Making red blood cells
B Pancreas producing insulin
C Pupil changing size
D Stomach producing acid
Your answer [1]
7 Scientists have developed a detailed understanding of the human genome.
Which of these is a benefit from developing this understanding?
A Discovering new antibiotics
B Explaining why antibiotic resistant bacteria have evolved
C Predicting whether a person will develop a genetic condition
D Using embryonic stem cells for transplants
Your answer [1]
© OCR 2025
20251202204138_692f4f024ffda_ngcr__40_.docx 4 20251202204138_692f4f024ffda_ngcr__40_.docx
