ONCC Practice Tests (OCN - Oncology
Nursing Practice 2025-2026)
Questions and Correct Answers
A patient with cancer is considering entering a clinical trial that compares the current standard
treatment with an investigational chemotherapeutic agent. This is an example of which phase of
a clinical trial?
A. 3
B. 4
C. 1
D. 2 - correct answer A: 3
Answer: Phase 3 clinical trials have a primary goal of establishing efficacy and comparing with
the current standard.
Reference: Eggert, J. (Ed.). (2017). Cancer basics (2nd ed.). Pittsburgh, PA: Oncology Nursing
Society, p. 285(t).
What is the shortest phase of the cell cycle?
A. Mitosis
B. Gap 1
C. Synthesis
D. Gap 2 - correct answer: Mitosis
Answer A: Mitosis is the shortest phase of the cell's life cycle.
, Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy and biotherapy
guidelines and recommendations for practice (4th ed.). Pittsburgh, PA: Oncology Nursing
Society, p. 25.
Oligodendroglia tumors originate from cells that maintain the function of the:
A. myelin sheath.
B. synovial fluid.
C. lymph.
D. plasma. - correct answer A: myelin sheath.
Answer: Oligodendrocytes are cells that develop and maintain the myelin sheath.
Reference: Yarbro, C.H., Wujcik, D., & Gobel, B.H. (Eds.). (2018). Cancer nursing: Principles and
practice (8th ed.). Burlington, MA: Jones and Bartlett, p. 1368.
A squamous cell carcinoma of the esophagus is most likely to arise from the:
A. proximal esophagus.
B. Schatzki's ring.
C. cricoid cartilage.
D. abdominal esophagus. - correct answer A: proximal esophagus.
Answer: A squamous cell carcinoma of the esophagus is most likely to arise from the proximal
esophagus.
Reference: Yarbro, C.H., Wujcik, D., & Gobel, B.H. (Eds.). (2018). Cancer nursing: Principles and
practice (8th ed.). Burlington, MA: Jones and Bartlett, p. 1538.
Nursing Practice 2025-2026)
Questions and Correct Answers
A patient with cancer is considering entering a clinical trial that compares the current standard
treatment with an investigational chemotherapeutic agent. This is an example of which phase of
a clinical trial?
A. 3
B. 4
C. 1
D. 2 - correct answer A: 3
Answer: Phase 3 clinical trials have a primary goal of establishing efficacy and comparing with
the current standard.
Reference: Eggert, J. (Ed.). (2017). Cancer basics (2nd ed.). Pittsburgh, PA: Oncology Nursing
Society, p. 285(t).
What is the shortest phase of the cell cycle?
A. Mitosis
B. Gap 1
C. Synthesis
D. Gap 2 - correct answer: Mitosis
Answer A: Mitosis is the shortest phase of the cell's life cycle.
, Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy and biotherapy
guidelines and recommendations for practice (4th ed.). Pittsburgh, PA: Oncology Nursing
Society, p. 25.
Oligodendroglia tumors originate from cells that maintain the function of the:
A. myelin sheath.
B. synovial fluid.
C. lymph.
D. plasma. - correct answer A: myelin sheath.
Answer: Oligodendrocytes are cells that develop and maintain the myelin sheath.
Reference: Yarbro, C.H., Wujcik, D., & Gobel, B.H. (Eds.). (2018). Cancer nursing: Principles and
practice (8th ed.). Burlington, MA: Jones and Bartlett, p. 1368.
A squamous cell carcinoma of the esophagus is most likely to arise from the:
A. proximal esophagus.
B. Schatzki's ring.
C. cricoid cartilage.
D. abdominal esophagus. - correct answer A: proximal esophagus.
Answer: A squamous cell carcinoma of the esophagus is most likely to arise from the proximal
esophagus.
Reference: Yarbro, C.H., Wujcik, D., & Gobel, B.H. (Eds.). (2018). Cancer nursing: Principles and
practice (8th ed.). Burlington, MA: Jones and Bartlett, p. 1538.
