NAPLEX INFECTIOUS DISEASE
2026/2027 ACTUAL QUESTIONS
WITH VERIFIED ANSWERS.
What are monitoring parameters for Cubicin? - correct answer-
check CK baseline and weekly, can cause rhabdo
What coverage does Dapto have? - correct answer-gram +,
MRSA and VRE
What drug gets inactivated by surfactants, making it ineffective
for pneumonia infections? - correct answer-Daptomycin
(CUBICIN)
What should you avoid with Flagyl? - correct answer-alcohol,
(disulfuram rxn)
What are possible risks associated with Metronidazole? -
correct answer-convulsive seizures, periph. Neuropathy, and
carcinogenicity
,What types of utis are covered with Nitrofurantoin? - correct
answer-E. Coli, S. Aureus, Enterococci, Kleb and Enterobacter,
Does NOT cover MRSA and Pseudomonas
What are contraindications to Macrobid? - correct answer-
significantly elevated scr, clcr < 60, pregnancy at 38-42 weeks
What abx can cause brown discolored urine? - correct answer-
nitrofurantoin
Tigacyl coverage: - correct answer-gram+ (including MRSA),
gram - and anaerobes
Does not cover VRE
A patient has a clcr < 60 ml/min, how do you adjust
Tigecycline? - correct answer-you don't, it doesn't require
adjustment for renal impairment.
, Name some antipseudomonal drugs? - correct answer-
ticarcillin, piperacillin, imipenem-cilastatin, meropenem,
aztreonam, ceftazidime, cefepime, Cipro, Levofloxacin,
aminoglycosides
Name some drugs that cover anaerobes - correct answer-BLI
pcns, imipenem-cilastatin, Meropenem, cefoxitin, clindamycin,
metronidazole
Name some very broad spectrum abx? - correct answer-
cefepime (maxipime), merrem, imipenem-cilastatin
What abx have hepatic metabolism? - correct answer-
ceftriaxone, macrolides, Synercid (quin/dalf)
Drug class of choice for atypical respiratory infection? - correct
answer-macrolides
Drug class of choice for mycobacteria? - correct answer-
macrolides
2026/2027 ACTUAL QUESTIONS
WITH VERIFIED ANSWERS.
What are monitoring parameters for Cubicin? - correct answer-
check CK baseline and weekly, can cause rhabdo
What coverage does Dapto have? - correct answer-gram +,
MRSA and VRE
What drug gets inactivated by surfactants, making it ineffective
for pneumonia infections? - correct answer-Daptomycin
(CUBICIN)
What should you avoid with Flagyl? - correct answer-alcohol,
(disulfuram rxn)
What are possible risks associated with Metronidazole? -
correct answer-convulsive seizures, periph. Neuropathy, and
carcinogenicity
,What types of utis are covered with Nitrofurantoin? - correct
answer-E. Coli, S. Aureus, Enterococci, Kleb and Enterobacter,
Does NOT cover MRSA and Pseudomonas
What are contraindications to Macrobid? - correct answer-
significantly elevated scr, clcr < 60, pregnancy at 38-42 weeks
What abx can cause brown discolored urine? - correct answer-
nitrofurantoin
Tigacyl coverage: - correct answer-gram+ (including MRSA),
gram - and anaerobes
Does not cover VRE
A patient has a clcr < 60 ml/min, how do you adjust
Tigecycline? - correct answer-you don't, it doesn't require
adjustment for renal impairment.
, Name some antipseudomonal drugs? - correct answer-
ticarcillin, piperacillin, imipenem-cilastatin, meropenem,
aztreonam, ceftazidime, cefepime, Cipro, Levofloxacin,
aminoglycosides
Name some drugs that cover anaerobes - correct answer-BLI
pcns, imipenem-cilastatin, Meropenem, cefoxitin, clindamycin,
metronidazole
Name some very broad spectrum abx? - correct answer-
cefepime (maxipime), merrem, imipenem-cilastatin
What abx have hepatic metabolism? - correct answer-
ceftriaxone, macrolides, Synercid (quin/dalf)
Drug class of choice for atypical respiratory infection? - correct
answer-macrolides
Drug class of choice for mycobacteria? - correct answer-
macrolides
