NU 664C BUNDLED PACKAGE FAMILY
PSYCHIATRIC STUDY GUIDE 2026 FULL
QUESTIONS AND SOLUTIONS
GUARANTEED PASS
◉ Know and describe the top atypical antipsychotic with greatest
incidence of prolonged QTc interval. Answer: Ziprasidone (Geodon).
Normal QTc =450.
>470, Call Cardiologist
>500, stop all meds.
Ziprasidone (Geodon) has been associated with a dose-related
prolongation of the QTc
QTc interval prolongation is greatest with ziprasidone and least with
olanzapine.
Ziprasidone (Geodon) an atypical antipsychotic (serotonin-dopamine
antagonist; second-generation antipsychotic; also a mood stabilizer.
Ziprasidone is prescribed for Schizophrenia, delaying relapse in
schizophrenia, acute agitation in schizophrenia (intramuscular), acute
mania/mixed mania, bipolar maintenance, other psychotic d/o, bipolar
depression, behavioral disturbances in dementias, behavioral
disturbances in children and adolescents, and disorders associated with
problems with impulse control.
Ziprasidone blocks dopamine 2 receptors, reducing positive symptoms
of psychosis and stabilizing affective symptoms. Blocks serotonin 2A
receptors, causing enhancement of dopamine release in certain brain
,regions and thus reducing motor side effects and possible improving
cognitive and affective symptoms.
EKGs may be useful for selected patients (e.g., those with personal or
family history of QTc prolongation; cardiac arrhythmia; recent
myocardial infarction; uncompensated heart failure; or those taking
agents that prolong QTc interval (such as pimozide, thioridazine,
selected antiarrhythmics, moxifloxacin, sparfloxacin, etc.)
Ziprasidone prolongs QTc interval more than some other antipsychotics.
Ziprasidone is associated with rare but serious skin condition known as
Drug Reaction with Eosinophilia (DRESS). DRESS may begin as a rash
but can progress to other parts of the body and can include symptoms
such as fever, swollen lymph nodes, swollen face, inflammation of
organs, and an increase in white blood cells known as eosinophilia. In
some cases, DRESS can lead to death. Clinic
◉ Know which antipsychotics have specific instructions for minimum
food intake or diet restrictions. Answer: Geodon because food affects the
absorption of the drug.
Lurasidone - Latuda
◉ Know an alternative atypical antipsychotic for a patient who has
developed diabetes and has a significant weight gain from treatment
with olanzapine. Answer: Abilify or Geodon, or Lurasidone (Latuda)
Because they are weight neutral or causes minimal weight gain.
◉ Know whether a patient is demonstrating efficacy to clozapine 500
mg/day if this week's granulocyte count is less than 500mm3. What is
the most appropriate recommendation for drug therapy? Answer: Stop
, the drug, because of the risk of agranulocytosis and patient can be
infected.
The most appropriate recommendation for drug therapy is to repeat CBC
weekly.
> 1500, watch carefully if is at 1000
◉ Know the common effects of smoking along with antipsychotic drug
therapy such as olanzapine. Answer: Smoking reduces the level of
Olanzapine because of its metabolism at CYP450 enzyme.
◉ Be able to describe three positive symptoms and three negative
symptoms of schizophrenia. Answer: Positive symptoms-Delusions,
Hallucinations, Ideas of reference, Catatonic, Disorganized speech,
thinking or behavior
Negative symptoms-Flat affect, Asocial, Monotone, Anhedonia,
Avolition, Isolation, Poverty of Speech, Decreased self-care
◉ Know what a painful muscle spasm with neck muscles pulling a
patient's head to the side called and Name a common drug therapy to
relieve this symptom. Answer: ·Torticollis or Acute Dystonic
The common drug therapy is Cogentin (Benztropine) relieves the
symptoms
Benadryl or Ativan can also be used.
◉ Know the role of buspirone in the treatment of anxiety and the
recommended dose and time for onset of action. Answer: Management
PSYCHIATRIC STUDY GUIDE 2026 FULL
QUESTIONS AND SOLUTIONS
GUARANTEED PASS
◉ Know and describe the top atypical antipsychotic with greatest
incidence of prolonged QTc interval. Answer: Ziprasidone (Geodon).
Normal QTc =450.
>470, Call Cardiologist
>500, stop all meds.
Ziprasidone (Geodon) has been associated with a dose-related
prolongation of the QTc
QTc interval prolongation is greatest with ziprasidone and least with
olanzapine.
Ziprasidone (Geodon) an atypical antipsychotic (serotonin-dopamine
antagonist; second-generation antipsychotic; also a mood stabilizer.
Ziprasidone is prescribed for Schizophrenia, delaying relapse in
schizophrenia, acute agitation in schizophrenia (intramuscular), acute
mania/mixed mania, bipolar maintenance, other psychotic d/o, bipolar
depression, behavioral disturbances in dementias, behavioral
disturbances in children and adolescents, and disorders associated with
problems with impulse control.
Ziprasidone blocks dopamine 2 receptors, reducing positive symptoms
of psychosis and stabilizing affective symptoms. Blocks serotonin 2A
receptors, causing enhancement of dopamine release in certain brain
,regions and thus reducing motor side effects and possible improving
cognitive and affective symptoms.
EKGs may be useful for selected patients (e.g., those with personal or
family history of QTc prolongation; cardiac arrhythmia; recent
myocardial infarction; uncompensated heart failure; or those taking
agents that prolong QTc interval (such as pimozide, thioridazine,
selected antiarrhythmics, moxifloxacin, sparfloxacin, etc.)
Ziprasidone prolongs QTc interval more than some other antipsychotics.
Ziprasidone is associated with rare but serious skin condition known as
Drug Reaction with Eosinophilia (DRESS). DRESS may begin as a rash
but can progress to other parts of the body and can include symptoms
such as fever, swollen lymph nodes, swollen face, inflammation of
organs, and an increase in white blood cells known as eosinophilia. In
some cases, DRESS can lead to death. Clinic
◉ Know which antipsychotics have specific instructions for minimum
food intake or diet restrictions. Answer: Geodon because food affects the
absorption of the drug.
Lurasidone - Latuda
◉ Know an alternative atypical antipsychotic for a patient who has
developed diabetes and has a significant weight gain from treatment
with olanzapine. Answer: Abilify or Geodon, or Lurasidone (Latuda)
Because they are weight neutral or causes minimal weight gain.
◉ Know whether a patient is demonstrating efficacy to clozapine 500
mg/day if this week's granulocyte count is less than 500mm3. What is
the most appropriate recommendation for drug therapy? Answer: Stop
, the drug, because of the risk of agranulocytosis and patient can be
infected.
The most appropriate recommendation for drug therapy is to repeat CBC
weekly.
> 1500, watch carefully if is at 1000
◉ Know the common effects of smoking along with antipsychotic drug
therapy such as olanzapine. Answer: Smoking reduces the level of
Olanzapine because of its metabolism at CYP450 enzyme.
◉ Be able to describe three positive symptoms and three negative
symptoms of schizophrenia. Answer: Positive symptoms-Delusions,
Hallucinations, Ideas of reference, Catatonic, Disorganized speech,
thinking or behavior
Negative symptoms-Flat affect, Asocial, Monotone, Anhedonia,
Avolition, Isolation, Poverty of Speech, Decreased self-care
◉ Know what a painful muscle spasm with neck muscles pulling a
patient's head to the side called and Name a common drug therapy to
relieve this symptom. Answer: ·Torticollis or Acute Dystonic
The common drug therapy is Cogentin (Benztropine) relieves the
symptoms
Benadryl or Ativan can also be used.
◉ Know the role of buspirone in the treatment of anxiety and the
recommended dose and time for onset of action. Answer: Management
