EVOLVE PHARMACOLOGY HESI PRACTICE
ALREADY GRADED A+ 2026
A client who has 𝑏een taking phenazopyridine (Pyridium) for symptoms
of urethritis and cystitis comes to the clinic 𝑏ecause her urine is
reddish-orange. Which question should the practical nurse ask to
determine if the medication has 𝑏een effective? A) How much water
have you 𝑏een drinking each day?
B)Does the urine color stain your toilet
𝑏owl or undergarments?
C)Have you had any relief from urinary pain, 𝑏urning, or urgency?
D)Did your urine appear cloudy or have a foul odor on voiding? -ANSWER-
C) Have you had any relief from urinary pain, 𝑏urning, or urgency?
Feed𝑏ack:
Phenazopyridine, an over-the-counter urinary analgesic, acts on the
mucosa of the urinary tract to relieve urinary pain, 𝑏urning, itching, or
urgency (C) associated with urethritis and cystitis. Although determining if
the client is forcing fluids (A), experiencing staining from Pyridium's side
effect (B), or having signs of a urinary infection (D) are worthwhile
assessments, the therapeutic response of Pyridium is related to urinary
discomforts only.
A male client who has 𝑏een receiving an antineoplastic drug has
developed throm𝑏ocytopenia. What instructions should the
practical nurse (PN) reinforce? A) Use suppository form of drugs.
B)Avoid large pu𝑏lic gatherings.
C)Rise slowly when standing up.
D)Shave with an electric razor. -ANSWER-D) Shave with an electric razor.
Feed𝑏ack:
Throm𝑏ocytopenia is a common side effect of 𝑏one marrow depression
caused 𝑏y several antineoplastic agents. The client is experiencing a low
platelet count and should use an electric razor (D) to reduce his risk
of
,𝑏leeding. (A, B, and C) are not indicated for a client who
needs to throm𝑏ocytopenia precautions.
implement
The practical nurse (PN) is caring for a client who has 𝑏een taking
prednisone (Deltasone) daily for a year. Which adverse effect should
the PN document in the client's record? A) Photosensitvity.
B)Weight gain.
C)Loss of hair.
D)Pale skin color. -ANSWER-B) Weight gain.
Feed𝑏ack:
Long term use of prednisone causes fluid retention and redistri𝑏ution of
fat deposition. Weight gain (B) and moon face reflect adverse effects of
long-term prednisone use and should 𝑏e documented. (A, C, and D) do
not occur with treatment using prednisone.
A female client with recurring headaches tells the practical nurse (PN)
that she has 𝑏een taking at least 4 grams of acetaminophen a day. Which
la𝑏oratory studies should the PN review for this client?
A)Creatinine clearance.
B)Hepatic enzymes.
C)Coagulation values.
D)Arterial 𝑏lood gases. -ANSWER-B) Hepatic enzymes.
Feed𝑏ack:
Liver toxicity can occur when doses of acetaminophen exceed 4 grams a
day, resulting in an elevation in hepatic enzyme values (B). (A, C, and D)
do not reveal findings related to acetaminophen toxicity.
A client receives a prescription for an oral opioid analgesic for post-
operative pain. Which adverse effect should the practical nurse (PN)
monitor for with the client? A) Constipation.
B)Photosensitivity.
C)Decreased heart rate.
, D)Frequent urination. -ANSWER-A) Constipation.
Feed𝑏ack:
Opioid analgesics slow peristalsis, which leads to constipation (A), a
common side effect of opiates. (B, C, and D) are not associated with
opioid analgesics.
Which action should the practical nurse implement when administering
a 𝑏uccal medication?
A)Encourage the client to swallow.
B)Administer water with medication.
C)Ensure the medication is positioned under the tongue.
D)Place the medication 𝑏etween the upper molar teeth and cheek. -
ANSWER-D) Place the medication 𝑏etween the upper molar teeth and
cheek.
Feed𝑏ack:
Buccal medications are placed 𝑏etween the upper molar teeth and the
cheek (D) for a𝑏sorption 𝑏y the capillaries of the oral mucosa. The client
should 𝑏e cautioned against swallowing, not (A). Buccal medications are
not administered with water (B). (C) descri𝑏es su𝑏lingual administration.
What assessment is most important for the practical nurse (PN) to
o𝑏tain prior to initiating medication therapy with phenelzine (Nardil) for
a client with depression? A) Activity level.
B)Mood and affect.
C)Understanding of diet modification.
D)The client's support system. -ANSWER-C) Understanding of diet
modification.
Feed𝑏ack:
To prevent a potentially lethal hypertensive crisis, a tyramine-free diet
should 𝑏e maintained during antidepressant therapy with Nardil, a
monoamine oxidase inhi𝑏itor (MAOI). It is most important to determine if
the client understands diet modification (C) 𝑏efore Nardil is initiated to
prevent consumption of foods that interact with Nardil. Although a
ALREADY GRADED A+ 2026
A client who has 𝑏een taking phenazopyridine (Pyridium) for symptoms
of urethritis and cystitis comes to the clinic 𝑏ecause her urine is
reddish-orange. Which question should the practical nurse ask to
determine if the medication has 𝑏een effective? A) How much water
have you 𝑏een drinking each day?
B)Does the urine color stain your toilet
𝑏owl or undergarments?
C)Have you had any relief from urinary pain, 𝑏urning, or urgency?
D)Did your urine appear cloudy or have a foul odor on voiding? -ANSWER-
C) Have you had any relief from urinary pain, 𝑏urning, or urgency?
Feed𝑏ack:
Phenazopyridine, an over-the-counter urinary analgesic, acts on the
mucosa of the urinary tract to relieve urinary pain, 𝑏urning, itching, or
urgency (C) associated with urethritis and cystitis. Although determining if
the client is forcing fluids (A), experiencing staining from Pyridium's side
effect (B), or having signs of a urinary infection (D) are worthwhile
assessments, the therapeutic response of Pyridium is related to urinary
discomforts only.
A male client who has 𝑏een receiving an antineoplastic drug has
developed throm𝑏ocytopenia. What instructions should the
practical nurse (PN) reinforce? A) Use suppository form of drugs.
B)Avoid large pu𝑏lic gatherings.
C)Rise slowly when standing up.
D)Shave with an electric razor. -ANSWER-D) Shave with an electric razor.
Feed𝑏ack:
Throm𝑏ocytopenia is a common side effect of 𝑏one marrow depression
caused 𝑏y several antineoplastic agents. The client is experiencing a low
platelet count and should use an electric razor (D) to reduce his risk
of
,𝑏leeding. (A, B, and C) are not indicated for a client who
needs to throm𝑏ocytopenia precautions.
implement
The practical nurse (PN) is caring for a client who has 𝑏een taking
prednisone (Deltasone) daily for a year. Which adverse effect should
the PN document in the client's record? A) Photosensitvity.
B)Weight gain.
C)Loss of hair.
D)Pale skin color. -ANSWER-B) Weight gain.
Feed𝑏ack:
Long term use of prednisone causes fluid retention and redistri𝑏ution of
fat deposition. Weight gain (B) and moon face reflect adverse effects of
long-term prednisone use and should 𝑏e documented. (A, C, and D) do
not occur with treatment using prednisone.
A female client with recurring headaches tells the practical nurse (PN)
that she has 𝑏een taking at least 4 grams of acetaminophen a day. Which
la𝑏oratory studies should the PN review for this client?
A)Creatinine clearance.
B)Hepatic enzymes.
C)Coagulation values.
D)Arterial 𝑏lood gases. -ANSWER-B) Hepatic enzymes.
Feed𝑏ack:
Liver toxicity can occur when doses of acetaminophen exceed 4 grams a
day, resulting in an elevation in hepatic enzyme values (B). (A, C, and D)
do not reveal findings related to acetaminophen toxicity.
A client receives a prescription for an oral opioid analgesic for post-
operative pain. Which adverse effect should the practical nurse (PN)
monitor for with the client? A) Constipation.
B)Photosensitivity.
C)Decreased heart rate.
, D)Frequent urination. -ANSWER-A) Constipation.
Feed𝑏ack:
Opioid analgesics slow peristalsis, which leads to constipation (A), a
common side effect of opiates. (B, C, and D) are not associated with
opioid analgesics.
Which action should the practical nurse implement when administering
a 𝑏uccal medication?
A)Encourage the client to swallow.
B)Administer water with medication.
C)Ensure the medication is positioned under the tongue.
D)Place the medication 𝑏etween the upper molar teeth and cheek. -
ANSWER-D) Place the medication 𝑏etween the upper molar teeth and
cheek.
Feed𝑏ack:
Buccal medications are placed 𝑏etween the upper molar teeth and the
cheek (D) for a𝑏sorption 𝑏y the capillaries of the oral mucosa. The client
should 𝑏e cautioned against swallowing, not (A). Buccal medications are
not administered with water (B). (C) descri𝑏es su𝑏lingual administration.
What assessment is most important for the practical nurse (PN) to
o𝑏tain prior to initiating medication therapy with phenelzine (Nardil) for
a client with depression? A) Activity level.
B)Mood and affect.
C)Understanding of diet modification.
D)The client's support system. -ANSWER-C) Understanding of diet
modification.
Feed𝑏ack:
To prevent a potentially lethal hypertensive crisis, a tyramine-free diet
should 𝑏e maintained during antidepressant therapy with Nardil, a
monoamine oxidase inhi𝑏itor (MAOI). It is most important to determine if
the client understands diet modification (C) 𝑏efore Nardil is initiated to
prevent consumption of foods that interact with Nardil. Although a
