ATI Pharmacology NGN Practice Questions (With
Answers)
1. Anticoagulants (Warfarin)
A nurse is teaching a client taking warfarin. Which statement indicates correct understanding?
A. “I will increase leafy green vegetables in my diet.”
B. “I will use a soft toothbrush.”
C. “I will take aspirin for headaches.”
D. “I will stop the medication if I have bruising.”
✔ Correct Answer: B
Rationale: Warfarin increases bleeding risk. A soft toothbrush reduces gum bleeding. Vitamin K foods
(leafy greens) should be consistent, not increased. Aspirin increases bleeding risk.
2. Insulin (NGN prioritization)
A client with type 1 diabetes has a blood glucose of 62 mg/dL. What is the nurse’s priority action?
A. Administer rapid-acting insulin
B. Give 15 g oral glucose
C. Recheck glucose in 2 hours
D. Give long-acting insulin
✔ Correct Answer: B
Rationale: This is hypoglycemia. Immediate treatment is fast-acting carbohydrates.
3. Antibiotics (Safety)
Which finding requires immediate intervention in a client receiving IV vancomycin?
A. Red man syndrome (flushing, itching)
B. Mild nausea
C. Decreased appetite
D. Drowsiness
✔ Correct Answer: A
Rationale: Red man syndrome indicates rapid infusion and histamine release; infusion must be slowed
immediately.
,4. NGN Case Style (ACE inhibitors)
A client taking lisinopril reports persistent dry cough.
What is the best nursing action?
A. Encourage fluid intake
B. Reassure this is expected and continue medication
C. Notify provider for possible medication change
D. Administer cough suppressant
✔ Correct Answer: C
Rationale: ACE inhibitors commonly cause persistent cough due to bradykinin buildup; may require
switching to ARB.
5. Priority Medication Safety
A nurse is preparing medications. Which action is correct?
A. Crush all oral meds for easier swallowing
B. Double-check high-alert medications independently
C. Skip ID check if patient is known
D. Administer meds prepared by another nurse
✔ Correct Answer: B
Rationale: High-alert meds require independent double-check for safety.
NGN Exam Focus Areas (ATI Pharmacology)
You should expect questions on:
• Anticoagulants (warfarin, heparin)
• Insulin types & hypoglycemia management
• Antibiotics & adverse effects
• Cardiovascular meds (beta blockers, ACE inhibitors)
• Psychiatric meds (SSRIs, antipsychotics)
• Medication safety & priority nursing actions
• NGN case-based clinical judgment
,Got it — here is a full ATI Pharmacology NGN-style 70-question mock exam with correct answers +
rationales, designed to match ATI testing patterns (priority, safety, delegation, and clinical judgment).
ATI Pharmacology NGN Mock Exam (70 Questions)
SECTION 1: SAFETY & PRIORITY (1–15)
1. A client receiving morphine has a respiratory rate of 8/min. What is the priority action?
A. Administer naloxone
B. Encourage deep breathing
C. Document findings
D. Reassess in 30 minutes
✔ Answer: A
Rationale: Respiratory depression is life-threatening; naloxone is the antidote.
2. Which medication requires monitoring for ototoxicity?
A. Amoxicillin
B. Furosemide
C. Metformin
D. Lisinopril
✔ Answer: B
Rationale: Loop diuretics can cause ototoxicity.
3. First action before administering any medication:
A. Check allergies
B. Ask pain level
C. Check pulse
D. Give water
✔ Answer: A
Rationale: Always verify allergies first.
4. A client taking heparin has bleeding gums. What should the nurse do first?
A. Stop infusion
B. Notify provider
, C. Apply pressure
D. Administer vitamin K
✔ Answer: C
Rationale: Apply direct pressure first to control bleeding.
5. Which lab result is most concerning for warfarin therapy?
A. INR 2.5
B. INR 3.0
C. INR 5.8
D. INR 1.8
✔ Answer: C
Rationale: INR >5 = high risk for bleeding.
6–15 (Safety & Priority Mix)
6. Digoxin toxicity sign → ✔ Blurred yellow vision
7. Hypoglycemia treatment → ✔ 15g glucose
8. Antidote for benzodiazepines → ✔ Flumazenil
9. Heparin antidote → ✔ Protamine sulfate
10. Opioid reversal → ✔ Naloxone
11. ACE inhibitor side effect → ✔ Dry cough
12. Lithium toxicity sign → ✔ Tremors, confusion
13. Potassium-sparing diuretic risk → ✔ Hyperkalemia
14. Priority in chest pain + nitro → ✔ Check BP first
15. IV infiltration sign → ✔ Cool, swollen site
SECTION 2: CARDIOVASCULAR DRUGS (16–30)
16. Beta blocker effect:
✔ ↓ heart rate
17. Lisinopril classification:
✔ ACE inhibitor
Answers)
1. Anticoagulants (Warfarin)
A nurse is teaching a client taking warfarin. Which statement indicates correct understanding?
A. “I will increase leafy green vegetables in my diet.”
B. “I will use a soft toothbrush.”
C. “I will take aspirin for headaches.”
D. “I will stop the medication if I have bruising.”
✔ Correct Answer: B
Rationale: Warfarin increases bleeding risk. A soft toothbrush reduces gum bleeding. Vitamin K foods
(leafy greens) should be consistent, not increased. Aspirin increases bleeding risk.
2. Insulin (NGN prioritization)
A client with type 1 diabetes has a blood glucose of 62 mg/dL. What is the nurse’s priority action?
A. Administer rapid-acting insulin
B. Give 15 g oral glucose
C. Recheck glucose in 2 hours
D. Give long-acting insulin
✔ Correct Answer: B
Rationale: This is hypoglycemia. Immediate treatment is fast-acting carbohydrates.
3. Antibiotics (Safety)
Which finding requires immediate intervention in a client receiving IV vancomycin?
A. Red man syndrome (flushing, itching)
B. Mild nausea
C. Decreased appetite
D. Drowsiness
✔ Correct Answer: A
Rationale: Red man syndrome indicates rapid infusion and histamine release; infusion must be slowed
immediately.
,4. NGN Case Style (ACE inhibitors)
A client taking lisinopril reports persistent dry cough.
What is the best nursing action?
A. Encourage fluid intake
B. Reassure this is expected and continue medication
C. Notify provider for possible medication change
D. Administer cough suppressant
✔ Correct Answer: C
Rationale: ACE inhibitors commonly cause persistent cough due to bradykinin buildup; may require
switching to ARB.
5. Priority Medication Safety
A nurse is preparing medications. Which action is correct?
A. Crush all oral meds for easier swallowing
B. Double-check high-alert medications independently
C. Skip ID check if patient is known
D. Administer meds prepared by another nurse
✔ Correct Answer: B
Rationale: High-alert meds require independent double-check for safety.
NGN Exam Focus Areas (ATI Pharmacology)
You should expect questions on:
• Anticoagulants (warfarin, heparin)
• Insulin types & hypoglycemia management
• Antibiotics & adverse effects
• Cardiovascular meds (beta blockers, ACE inhibitors)
• Psychiatric meds (SSRIs, antipsychotics)
• Medication safety & priority nursing actions
• NGN case-based clinical judgment
,Got it — here is a full ATI Pharmacology NGN-style 70-question mock exam with correct answers +
rationales, designed to match ATI testing patterns (priority, safety, delegation, and clinical judgment).
ATI Pharmacology NGN Mock Exam (70 Questions)
SECTION 1: SAFETY & PRIORITY (1–15)
1. A client receiving morphine has a respiratory rate of 8/min. What is the priority action?
A. Administer naloxone
B. Encourage deep breathing
C. Document findings
D. Reassess in 30 minutes
✔ Answer: A
Rationale: Respiratory depression is life-threatening; naloxone is the antidote.
2. Which medication requires monitoring for ototoxicity?
A. Amoxicillin
B. Furosemide
C. Metformin
D. Lisinopril
✔ Answer: B
Rationale: Loop diuretics can cause ototoxicity.
3. First action before administering any medication:
A. Check allergies
B. Ask pain level
C. Check pulse
D. Give water
✔ Answer: A
Rationale: Always verify allergies first.
4. A client taking heparin has bleeding gums. What should the nurse do first?
A. Stop infusion
B. Notify provider
, C. Apply pressure
D. Administer vitamin K
✔ Answer: C
Rationale: Apply direct pressure first to control bleeding.
5. Which lab result is most concerning for warfarin therapy?
A. INR 2.5
B. INR 3.0
C. INR 5.8
D. INR 1.8
✔ Answer: C
Rationale: INR >5 = high risk for bleeding.
6–15 (Safety & Priority Mix)
6. Digoxin toxicity sign → ✔ Blurred yellow vision
7. Hypoglycemia treatment → ✔ 15g glucose
8. Antidote for benzodiazepines → ✔ Flumazenil
9. Heparin antidote → ✔ Protamine sulfate
10. Opioid reversal → ✔ Naloxone
11. ACE inhibitor side effect → ✔ Dry cough
12. Lithium toxicity sign → ✔ Tremors, confusion
13. Potassium-sparing diuretic risk → ✔ Hyperkalemia
14. Priority in chest pain + nitro → ✔ Check BP first
15. IV infiltration sign → ✔ Cool, swollen site
SECTION 2: CARDIOVASCULAR DRUGS (16–30)
16. Beta blocker effect:
✔ ↓ heart rate
17. Lisinopril classification:
✔ ACE inhibitor
