Pharmacotherapeutics for Advanced
Practice Nurse Prescribers (6th Ed) by
Woo & Wright|
🧪 Pharmacotherapeutics Practice Test
1. Prescriptive authority for nurse practitioners is primarily regulated by:
A. DEA
B. FDA
C. State Board of Nursing
D. CDC
✅ Answer: C
Rationale: Authority varies by state and is governed by nursing boards.
2. Which factor MOST influences drug metabolism?
A. Gender
B. Liver function
C. Height
D. Eye color
✅ Answer: B
Rationale: The liver is the main organ for drug metabolism.
3. First-pass metabolism occurs in the:
,A. Kidneys
B. Liver
C. Lungs
D. Intestines
✅ Answer: B
4. A drug with a narrow therapeutic index requires:
A. No monitoring
B. Frequent monitoring
C. High doses
D. PRN dosing
✅ Answer: B
5. Bioavailability refers to:
A. Drug half-life
B. Drug absorption into systemic circulation
C. Drug excretion
D. Drug toxicity
✅ Answer: B
6. The half-life of a drug determines:
A. Drug color
B. Dosing frequency
C. Route of administration
D. Drug cost
✅ Answer: B
7. Which receptor interaction produces the strongest response?
A. Antagonist
B. Partial agonist
C. Full agonist
D. Inhibitor
✅ Answer: C
,8. Drug excretion primarily occurs via the:
A. Lungs
B. Skin
C. Kidneys
D. Brain
✅ Answer: C
9. A loading dose is used to:
A. Maintain drug levels
B. Quickly reach therapeutic levels
C. Reduce toxicity
D. Delay action
✅ Answer: B
10. Which route avoids first-pass metabolism?
A. Oral
B. Sublingual
C. Rectal
D. Enteral
✅ Answer: B
11. An adverse drug reaction is:
A. Expected response
B. Harmful unintended effect
C. Placebo effect
D. Desired effect
✅ Answer: B
12. Pharmacodynamics refers to:
A. Drug absorption
B. Drug metabolism
C. Drug effects on the body
D. Drug excretion
✅ Answer: C
, 13. Pharmacokinetics includes:
A. Drug response
B. ADME
C. Side effects
D. Drug allergies
✅ Answer: B
14. Which population is MOST at risk for toxicity?
A. Adolescents
B. Elderly
C. Athletes
D. Adults
✅ Answer: B
15. Therapeutic drug monitoring is used for:
A. Safe drugs
B. Narrow index drugs
C. OTC drugs
D. Herbal drugs
✅ Answer: B
16. A competitive antagonist:
A. Irreversibly binds
B. Competes for receptor
C. Activates receptor
D. Destroys receptor
✅ Answer: B
17. Drug tolerance means:
A. Increased effect
B. Decreased response
C. Allergy
D. Toxicity