Onset and Duration of
Action – Practice HIGH
FLIYER 2025-2026
VERSION WITH 100%
QUALITY QUESTIONS
AND VERRIFIED
ANSWERS.
1. Which insulin has the fastest onset of
action?
A. NPH
,B. Regular insulin
C. Lispro
D. Glargine
Answer: C. Lispro
Rationale: Rapid-acting insulin (lispro) has
onset in 10–15 minutes, making it the
fastest among insulins.
2. Which insulin has the longest duration of
action?
A. Regular
B. NPH
C. Glargine
D. Lispro
,Answer: C. Glargine
Rationale: Glargine is a long-acting insulin
with no peak and duration up to 24 hours.
3. A nurse administers IV morphine. What
is the onset of action?
A. 30–60 minutes
B. 15–30 minutes
C. 5–10 minutes
D. 1–2 hours
Answer: C. 5–10 minutes
Rationale: IV administration produces the
fastest onset due to direct bloodstream
delivery.
, 4. Which route has the slowest onset of
action?
A. IV
B. IM
C. Oral
D. Subcutaneous
Answer: C. Oral
Rationale: Oral medications must pass
through digestion and first-pass
metabolism.
5. A nurse knows subcutaneous heparin
has what onset?
A. Immediate
B. 20–30 minutes
C. 2–4 hours
D. 6–8 hours
Action – Practice HIGH
FLIYER 2025-2026
VERSION WITH 100%
QUALITY QUESTIONS
AND VERRIFIED
ANSWERS.
1. Which insulin has the fastest onset of
action?
A. NPH
,B. Regular insulin
C. Lispro
D. Glargine
Answer: C. Lispro
Rationale: Rapid-acting insulin (lispro) has
onset in 10–15 minutes, making it the
fastest among insulins.
2. Which insulin has the longest duration of
action?
A. Regular
B. NPH
C. Glargine
D. Lispro
,Answer: C. Glargine
Rationale: Glargine is a long-acting insulin
with no peak and duration up to 24 hours.
3. A nurse administers IV morphine. What
is the onset of action?
A. 30–60 minutes
B. 15–30 minutes
C. 5–10 minutes
D. 1–2 hours
Answer: C. 5–10 minutes
Rationale: IV administration produces the
fastest onset due to direct bloodstream
delivery.
, 4. Which route has the slowest onset of
action?
A. IV
B. IM
C. Oral
D. Subcutaneous
Answer: C. Oral
Rationale: Oral medications must pass
through digestion and first-pass
metabolism.
5. A nurse knows subcutaneous heparin
has what onset?
A. Immediate
B. 20–30 minutes
C. 2–4 hours
D. 6–8 hours
