NSG 3280 - EXAM 3 (NEURO) QUESTIONS &
CORRECT ANSWERS (100% GRADE A+)
LATEST UPDATED 2026\2027
Whatghappensgtognervegtissuegduringgischemia?g-gCORRECTgANSWER-
Nervegtissuegstrugglesgwithganaerobicgmetabolismgandgisgverygsensitivegtogdecreasedgoxygen.
Whatgisgischemia?g-gCORRECTgANSWER-Cellgdeath.
Whatgisghypoxia?g-gCORRECTgANSWER-
Decreasedgoxygengleadinggtogmitochondrialgfailuregandgcellgdamage.
WhatgisgthegmaingCNSgneurotransmitter?g-gCORRECTgANSWER-Glutamate.
Whatgeffectgdoesgischemiaghavegongglutamate?g-gCORRECTgANSWER-
Ischemiagincreasesgglutamategrelease.
Whatgaregthegeffectsgofgtoogmuchgglutamate?g-gCORRECTgANSWER-
Increasedgcalciumgandgwatergentergthegcell,gcausinggcalciumgoverloadgandgcytotoxicgedema.
Whatgdoesgexcessivegglutamategproductiongleadgto?g-gCORRECTgANSWER-
Increasedgproductiongofgnitrousgoxide,gfreegradicalgformation,gandgcellgdeath.
Whatgisgthegnormalgrangegforgintracranialgpressureg(ICP)?g-gCORRECTgANSWER-0-15gmmHg
AtgwhatgICPglevelgdoesgbraingimpairmentgoccur?g-gCORRECTgANSWER->g22gmmHggforg>g5gminutes
WhatgaregthegthreegmaingcomponentsgofgthegcranialgcavitygaccordinggtogthegMonroe-Kelliegdoctrine?g-
gCORRECTgANSWER-Brain,gCerebrospinalgFluidg(CSF),gBlood
,Whatgisgintracranialgcompliance?g-gCORRECTgANSWER-
ThegabilitygofgthegcranialgcomponentsgtogadjustgtogchangesgingvolumegtogminimizegimpactgongICP.
NamegangeverydaygactivitygthatgcangcausegslightgchangesgingICP.g-gCORRECTgANSWER-
Sneeze,gcough,gbending,glaugh
Whatgisginterstitialgedema?g-gCORRECTgANSWER-
Swellinggcausedgbygfluid,gelectrolytes,gandgproteinsgforcedgintogthegintercellulargspacegduegtogvesselgdama
gegorgincreasedgpressure.
Whatgcausesgintracellulargedema?g-gCORRECTgANSWER-
GlobalgischemiagleadinggtogcellulargenergygfailuregandgNa+gaccumulation,gattractinggwatergintogthegcell.
WhatgisgthegmostgsensitivegclinicalgmanifestationgofgincreasedgICP?g-gCORRECTgANSWER-
Changeginglevelgofgconsciousnessg(LOC),goftengincreasedgdrowsiness.
WhatgaregcommongsymptomsgofgincreasedgICP?g-gCORRECTgANSWER-
Headache,gnausea/vomiting,gblurredgvision,gslowgpupillarygresponse.
WhatgisgCushing'sgTriad?g-gCORRECTgANSWER-
AglategsigngofgincreasedgICPgcharacterizedgbyg↑BP,g↓HR,gandgrespiratorygchanges.
WhatgdoesgagdecreasegingthegGlasgowgComagScaleg(GCS)gscoregindicate?g-gCORRECTgANSWER-
Agpotentialgdecreasegingconsciousnessgorgbraingfunction.
WhatgisgthegmaximumgscoregforgeyegopeninggongthegGlasgowgComagScale?g-gCORRECTgANSWER-
4gforgspontaneousgeyegopening.
WhatgisgthegmaximumgscoregforgverbalgresponsegongthegGlasgowgComagScale?g-gCORRECTgANSWER-
5gforgorientedgverbalgresponse.
WhatgisgthegmaximumgscoregforgmotorgresponsegongthegGlasgowgComagScale?g-gCORRECTgANSWER-
6gforgfollowinggcommands.
,Whatgdoesgdecreasedgpupilgresponsegindicate?g-gCORRECTgANSWER-Increasedgintracranialgpressureg(ICP).
WhatgisgthegnormalgresponsegingthegDoll'sgEyesgTest?g-gCORRECTgANSWER-
Eyesgmovegingthegoppositegdirectiongofgheadgmovement.
WhatgdoesgangabsentgresponsegingthegColdgCaloricsgtestgindicate?g-gCORRECTgANSWER-
Nogeyegmovement,gsuggestinggpotentialgbraingdysfunction.
Whatgisgthegnormalgresponsegofgthegcornealgreflex?g-gCORRECTgANSWER-
Blinkinggwhengagcottongswabgtouchesgthegcornea.
Whatgdoesgfixedgandgdilatedgpupilsgindicate?g-gCORRECTgANSWER-Poorgbraingperfusion.
Whatgdoesgsmallg(pinpoint)gpupilsgsuggest?g-gCORRECTgANSWER-Possiblegponsgissuegorgdruggeffects.
Focalg(Coup)g-gCORRECTgANSWER-Injuryglocalizedgtogthegsitegofgimpact
Polarg(Coup-countercoup)g-gCORRECTgANSWER-
Injurygatgsitegofgimpactgandgongoppositegsidegofgthegbraing(duegtogbrain'sgforward-
backwardgmovementgwithingthegskull)
Diffuseg-gCORRECTgANSWER-Widespreadgdamagegofgthegbrain
Multiplegmovementsgofgbraingwithingthegskullg-gCORRECTgANSWER-
Resultsgingshiftinggandgrotationalgforcesgcausesgstretchinggandgshearinggofgwhitegmatter
Primarygvsgsecondaryginjuryg-gCORRECTgANSWER-Primaryg-goriginalginjury;gSecondaryg-
gcomplicationsgthatgformgduegtogthegbodiesgresponsegtogthegprimaryginjury
Examplesgofgsecondaryginjuryg-gCORRECTgANSWER-
Cerebralgedema,gvesselgrebleedgorgspasm,gCSFgblockage,gseizures
, EpiduralgHematomag-gCORRECTgANSWER-Location:gbetweenginnergskullgandgduragmater
SubduralgHematomag-gCORRECTgANSWER-Location:gbetweengduragandgoutergarachnoidgmembrane
Subarachnoidghemorrhageg-gCORRECTgANSWER-
Location:gBetweengoutergarachnoidgmembranegandgpiagmater
ThromboticgStrokeg-gCORRECTgANSWER-Clotgformsgatgthegsitegofgatheroscleroticgplaque.
EmbolicgStrokeg-gCORRECTgANSWER-Clotgorgplaquegtravelsgtogthegbrain.
IrreversiblegDamageg-gCORRECTgANSWER-Beginsgaftergjustgseveralgminutes.
SymptomsgOnsetg-gCORRECTgANSWER-Startgtogshowgaftergaboutg1gminute.
InfarctiongandgNecrosisg-gCORRECTgANSWER-Happengaftergagfewghours.
Penumbrag-gCORRECTgANSWER-Areagaroundgnecrosisgthat'sgstillgviablegduegtogcollateralgcirculation.
LacunargInfarctsg-gCORRECTgANSWER-Occlusionsgofgarterioles.
CausesgofgLacunargInfarctsg-gCORRECTgANSWER-OftengduegtogHTNgorgdiabetes.
RiskgFactor:gAtherosclerosisg-gCORRECTgANSWER-Plaquegingarteries.
RiskgFactor:gCarotidgStenosisg-gCORRECTgANSWER-Narrowedgcarotidgarteriesgduegtogplaque.
RiskgFactor:gHTNg-gCORRECTgANSWER-Hypertension.
CORRECT ANSWERS (100% GRADE A+)
LATEST UPDATED 2026\2027
Whatghappensgtognervegtissuegduringgischemia?g-gCORRECTgANSWER-
Nervegtissuegstrugglesgwithganaerobicgmetabolismgandgisgverygsensitivegtogdecreasedgoxygen.
Whatgisgischemia?g-gCORRECTgANSWER-Cellgdeath.
Whatgisghypoxia?g-gCORRECTgANSWER-
Decreasedgoxygengleadinggtogmitochondrialgfailuregandgcellgdamage.
WhatgisgthegmaingCNSgneurotransmitter?g-gCORRECTgANSWER-Glutamate.
Whatgeffectgdoesgischemiaghavegongglutamate?g-gCORRECTgANSWER-
Ischemiagincreasesgglutamategrelease.
Whatgaregthegeffectsgofgtoogmuchgglutamate?g-gCORRECTgANSWER-
Increasedgcalciumgandgwatergentergthegcell,gcausinggcalciumgoverloadgandgcytotoxicgedema.
Whatgdoesgexcessivegglutamategproductiongleadgto?g-gCORRECTgANSWER-
Increasedgproductiongofgnitrousgoxide,gfreegradicalgformation,gandgcellgdeath.
Whatgisgthegnormalgrangegforgintracranialgpressureg(ICP)?g-gCORRECTgANSWER-0-15gmmHg
AtgwhatgICPglevelgdoesgbraingimpairmentgoccur?g-gCORRECTgANSWER->g22gmmHggforg>g5gminutes
WhatgaregthegthreegmaingcomponentsgofgthegcranialgcavitygaccordinggtogthegMonroe-Kelliegdoctrine?g-
gCORRECTgANSWER-Brain,gCerebrospinalgFluidg(CSF),gBlood
,Whatgisgintracranialgcompliance?g-gCORRECTgANSWER-
ThegabilitygofgthegcranialgcomponentsgtogadjustgtogchangesgingvolumegtogminimizegimpactgongICP.
NamegangeverydaygactivitygthatgcangcausegslightgchangesgingICP.g-gCORRECTgANSWER-
Sneeze,gcough,gbending,glaugh
Whatgisginterstitialgedema?g-gCORRECTgANSWER-
Swellinggcausedgbygfluid,gelectrolytes,gandgproteinsgforcedgintogthegintercellulargspacegduegtogvesselgdama
gegorgincreasedgpressure.
Whatgcausesgintracellulargedema?g-gCORRECTgANSWER-
GlobalgischemiagleadinggtogcellulargenergygfailuregandgNa+gaccumulation,gattractinggwatergintogthegcell.
WhatgisgthegmostgsensitivegclinicalgmanifestationgofgincreasedgICP?g-gCORRECTgANSWER-
Changeginglevelgofgconsciousnessg(LOC),goftengincreasedgdrowsiness.
WhatgaregcommongsymptomsgofgincreasedgICP?g-gCORRECTgANSWER-
Headache,gnausea/vomiting,gblurredgvision,gslowgpupillarygresponse.
WhatgisgCushing'sgTriad?g-gCORRECTgANSWER-
AglategsigngofgincreasedgICPgcharacterizedgbyg↑BP,g↓HR,gandgrespiratorygchanges.
WhatgdoesgagdecreasegingthegGlasgowgComagScaleg(GCS)gscoregindicate?g-gCORRECTgANSWER-
Agpotentialgdecreasegingconsciousnessgorgbraingfunction.
WhatgisgthegmaximumgscoregforgeyegopeninggongthegGlasgowgComagScale?g-gCORRECTgANSWER-
4gforgspontaneousgeyegopening.
WhatgisgthegmaximumgscoregforgverbalgresponsegongthegGlasgowgComagScale?g-gCORRECTgANSWER-
5gforgorientedgverbalgresponse.
WhatgisgthegmaximumgscoregforgmotorgresponsegongthegGlasgowgComagScale?g-gCORRECTgANSWER-
6gforgfollowinggcommands.
,Whatgdoesgdecreasedgpupilgresponsegindicate?g-gCORRECTgANSWER-Increasedgintracranialgpressureg(ICP).
WhatgisgthegnormalgresponsegingthegDoll'sgEyesgTest?g-gCORRECTgANSWER-
Eyesgmovegingthegoppositegdirectiongofgheadgmovement.
WhatgdoesgangabsentgresponsegingthegColdgCaloricsgtestgindicate?g-gCORRECTgANSWER-
Nogeyegmovement,gsuggestinggpotentialgbraingdysfunction.
Whatgisgthegnormalgresponsegofgthegcornealgreflex?g-gCORRECTgANSWER-
Blinkinggwhengagcottongswabgtouchesgthegcornea.
Whatgdoesgfixedgandgdilatedgpupilsgindicate?g-gCORRECTgANSWER-Poorgbraingperfusion.
Whatgdoesgsmallg(pinpoint)gpupilsgsuggest?g-gCORRECTgANSWER-Possiblegponsgissuegorgdruggeffects.
Focalg(Coup)g-gCORRECTgANSWER-Injuryglocalizedgtogthegsitegofgimpact
Polarg(Coup-countercoup)g-gCORRECTgANSWER-
Injurygatgsitegofgimpactgandgongoppositegsidegofgthegbraing(duegtogbrain'sgforward-
backwardgmovementgwithingthegskull)
Diffuseg-gCORRECTgANSWER-Widespreadgdamagegofgthegbrain
Multiplegmovementsgofgbraingwithingthegskullg-gCORRECTgANSWER-
Resultsgingshiftinggandgrotationalgforcesgcausesgstretchinggandgshearinggofgwhitegmatter
Primarygvsgsecondaryginjuryg-gCORRECTgANSWER-Primaryg-goriginalginjury;gSecondaryg-
gcomplicationsgthatgformgduegtogthegbodiesgresponsegtogthegprimaryginjury
Examplesgofgsecondaryginjuryg-gCORRECTgANSWER-
Cerebralgedema,gvesselgrebleedgorgspasm,gCSFgblockage,gseizures
, EpiduralgHematomag-gCORRECTgANSWER-Location:gbetweenginnergskullgandgduragmater
SubduralgHematomag-gCORRECTgANSWER-Location:gbetweengduragandgoutergarachnoidgmembrane
Subarachnoidghemorrhageg-gCORRECTgANSWER-
Location:gBetweengoutergarachnoidgmembranegandgpiagmater
ThromboticgStrokeg-gCORRECTgANSWER-Clotgformsgatgthegsitegofgatheroscleroticgplaque.
EmbolicgStrokeg-gCORRECTgANSWER-Clotgorgplaquegtravelsgtogthegbrain.
IrreversiblegDamageg-gCORRECTgANSWER-Beginsgaftergjustgseveralgminutes.
SymptomsgOnsetg-gCORRECTgANSWER-Startgtogshowgaftergaboutg1gminute.
InfarctiongandgNecrosisg-gCORRECTgANSWER-Happengaftergagfewghours.
Penumbrag-gCORRECTgANSWER-Areagaroundgnecrosisgthat'sgstillgviablegduegtogcollateralgcirculation.
LacunargInfarctsg-gCORRECTgANSWER-Occlusionsgofgarterioles.
CausesgofgLacunargInfarctsg-gCORRECTgANSWER-OftengduegtogHTNgorgdiabetes.
RiskgFactor:gAtherosclerosisg-gCORRECTgANSWER-Plaquegingarteries.
RiskgFactor:gCarotidgStenosisg-gCORRECTgANSWER-Narrowedgcarotidgarteriesgduegtogplaque.
RiskgFactor:gHTNg-gCORRECTgANSWER-Hypertension.