MCB 100 Exam 4 Study Material UPDATED ACTUAL Questions And Correct
Answers
C
Terms in this set (340)
Which of the following statements is TRUE of selective d. Selective toxicity takes advantage of structural and/or metabolic differences
toxicity? between host and pathogen
a. To be effective, an antimicrobial agent must be more
toxic to the patient than the pathogen
b. Selective toxicity takes advantage of differences in
metabolic rates of the host and pathogen
c. Selective toxicity takes advantage of structural
similarities between host and pathogen
d. Selective toxicity takes advantage of structural and/or
metabolic differences between host and pathogen
e. Selective toxicity damages only pathogenic
Which of the following is NOT a mode of action of c. Inhibition of flagella formation
antimicrobial drugs?
a. Inhibition of protein synthesis
b. Inhibition of cell wall synthesis
c. Inhibition of flagella formation
d. Inhibition of nucleic acid synthesis
Disruption of the normal microbiota can result in e. Both Candida albicans and Clostridium difficile
infections caused by which of the following microbes?
a. Candida albicans
b. Mycobacterium
c. Clostridium difficile
d. Streptococcus
e. Both Candida albicans and Clostridium difficile
Which of the following is NOT associated with microbial c. Denaturation of proteins
mechanisms of resistance? - Proteins are not denatured by antimicrobial drugs
a. Porins
b. Beta-lactamases
c. Denaturation of proteins
d. MfpA protein
,What major cellular feature that might be targeted by d. A cell wall
antimicrobial drugs is found in both bacteria and fungi
but not in human cells?
a. Ribosomes
b. DNA
c. Enzymes
d. A cell wall
Most broad-spectrum antibiotics act by: a. Inhibiting protein synthesis
a. Inhibiting protein synthesis
b. Inhibiting metabolic pathways
c. Inhibiting nucleic acid synthesis
d. Disrupting the cytoplasmic membrane
e. Inhibiting the synthesis of the cell wall
Sulfonamide drugs inhibit microbial growth by disrupting b. Competitive inhibition
metabolic pathways. What general mechanism do these
drugs use?
a. Noncompetitive inhibition
b. Competitive inhibition
c. Destruction of PABA
d. Disruption of tubulin polymerization
When a nurse rubs your skin with rubbing alcohol prior to a. Antisepsis
administering an injection, what process(es) is he carrying d. Degerming
out? Select all that apply
a. Antisepsis
b. Disinfection
c. Sanitization
d. Degerming
Which of the following is NOT an important consideration a. Whether or not hand sanitizer is available at the changing table
when preparing to use a chemical to disinfect a diaper
changing table in a public restroom?
a. Whether or not hand sanitizer is available at the
changing table
b. The label directions for contact timeWhether or not the
changing table is visibly soiled
c. Whether or not the chemical is compatible with the
material that the changing table is made of
Many MRSA strains are sensitive to other antibiotics. b. Disk diffusion
Which of the following methods would be the best way
to evaluate sensitivity to other antibiotics?
a. Growth on high salts
b. Disk diffusion
c. Assay for a PBP2a allele
d. Gram stain
, In examining a MRSA strain, researchers find that d. Production of a beta-lactamase
degraded penicillin is found in the culture medium. What
is the most likely mechanism of resistance?
a. Alteration of a porin
b. Alteration of a penicillin-binding protein (PBP)
c. Production of an efflux pump
d. Production of a beta-lactamase
Clostridium difficile is a common healthcare associated 1. Soap and water
infection. It is a Gram-positive spore-forming anaerobe 2. Use of Gloves
that is associated with antibiotic therapy. It is most 3. Use of approved chemicals
commonly transferred between patients on the hands of 4. Hand hygiene with gels
health care workers. Based on this information, rank the
following prevention and control strategies from most
beneficial (1) to least beneficial (4)
- Soap and water
- Use of approved chemicals
- Use of Gloves
- Use of approved chemicals
Some bacteria are resistant to antimicrobials due to the e. Efflux pumps
activity of ____ , which removes many of them
a. Lipopolysaccharides
b. Porins
c. Plasmids
d. Ribosomes
e. Efflux pumps
Prokaryotes contain _____ ribosomes b. 70S
a. 30S
b. 70S
c. 80S
d. 50S
Antimicrobial drugs are selectively toxic. This means _____ c. The drugs are more toxic to the pathogens than to the patient
a. The drugs will affect only a particular type of pathogen
b. The drugs are reactive within a specific part of the
patient's anatomy (for example, the inner ear)
c. The drugs are more toxic to the pathogens than to the
patient
d. The drugs will not have toxic effects on a patient
The tRNA molecule holding a growing polypeptide chain b. P site
is at the _ _.
a. E site
b. P site
c. 50S site
d. A site
Answers
C
Terms in this set (340)
Which of the following statements is TRUE of selective d. Selective toxicity takes advantage of structural and/or metabolic differences
toxicity? between host and pathogen
a. To be effective, an antimicrobial agent must be more
toxic to the patient than the pathogen
b. Selective toxicity takes advantage of differences in
metabolic rates of the host and pathogen
c. Selective toxicity takes advantage of structural
similarities between host and pathogen
d. Selective toxicity takes advantage of structural and/or
metabolic differences between host and pathogen
e. Selective toxicity damages only pathogenic
Which of the following is NOT a mode of action of c. Inhibition of flagella formation
antimicrobial drugs?
a. Inhibition of protein synthesis
b. Inhibition of cell wall synthesis
c. Inhibition of flagella formation
d. Inhibition of nucleic acid synthesis
Disruption of the normal microbiota can result in e. Both Candida albicans and Clostridium difficile
infections caused by which of the following microbes?
a. Candida albicans
b. Mycobacterium
c. Clostridium difficile
d. Streptococcus
e. Both Candida albicans and Clostridium difficile
Which of the following is NOT associated with microbial c. Denaturation of proteins
mechanisms of resistance? - Proteins are not denatured by antimicrobial drugs
a. Porins
b. Beta-lactamases
c. Denaturation of proteins
d. MfpA protein
,What major cellular feature that might be targeted by d. A cell wall
antimicrobial drugs is found in both bacteria and fungi
but not in human cells?
a. Ribosomes
b. DNA
c. Enzymes
d. A cell wall
Most broad-spectrum antibiotics act by: a. Inhibiting protein synthesis
a. Inhibiting protein synthesis
b. Inhibiting metabolic pathways
c. Inhibiting nucleic acid synthesis
d. Disrupting the cytoplasmic membrane
e. Inhibiting the synthesis of the cell wall
Sulfonamide drugs inhibit microbial growth by disrupting b. Competitive inhibition
metabolic pathways. What general mechanism do these
drugs use?
a. Noncompetitive inhibition
b. Competitive inhibition
c. Destruction of PABA
d. Disruption of tubulin polymerization
When a nurse rubs your skin with rubbing alcohol prior to a. Antisepsis
administering an injection, what process(es) is he carrying d. Degerming
out? Select all that apply
a. Antisepsis
b. Disinfection
c. Sanitization
d. Degerming
Which of the following is NOT an important consideration a. Whether or not hand sanitizer is available at the changing table
when preparing to use a chemical to disinfect a diaper
changing table in a public restroom?
a. Whether or not hand sanitizer is available at the
changing table
b. The label directions for contact timeWhether or not the
changing table is visibly soiled
c. Whether or not the chemical is compatible with the
material that the changing table is made of
Many MRSA strains are sensitive to other antibiotics. b. Disk diffusion
Which of the following methods would be the best way
to evaluate sensitivity to other antibiotics?
a. Growth on high salts
b. Disk diffusion
c. Assay for a PBP2a allele
d. Gram stain
, In examining a MRSA strain, researchers find that d. Production of a beta-lactamase
degraded penicillin is found in the culture medium. What
is the most likely mechanism of resistance?
a. Alteration of a porin
b. Alteration of a penicillin-binding protein (PBP)
c. Production of an efflux pump
d. Production of a beta-lactamase
Clostridium difficile is a common healthcare associated 1. Soap and water
infection. It is a Gram-positive spore-forming anaerobe 2. Use of Gloves
that is associated with antibiotic therapy. It is most 3. Use of approved chemicals
commonly transferred between patients on the hands of 4. Hand hygiene with gels
health care workers. Based on this information, rank the
following prevention and control strategies from most
beneficial (1) to least beneficial (4)
- Soap and water
- Use of approved chemicals
- Use of Gloves
- Use of approved chemicals
Some bacteria are resistant to antimicrobials due to the e. Efflux pumps
activity of ____ , which removes many of them
a. Lipopolysaccharides
b. Porins
c. Plasmids
d. Ribosomes
e. Efflux pumps
Prokaryotes contain _____ ribosomes b. 70S
a. 30S
b. 70S
c. 80S
d. 50S
Antimicrobial drugs are selectively toxic. This means _____ c. The drugs are more toxic to the pathogens than to the patient
a. The drugs will affect only a particular type of pathogen
b. The drugs are reactive within a specific part of the
patient's anatomy (for example, the inner ear)
c. The drugs are more toxic to the pathogens than to the
patient
d. The drugs will not have toxic effects on a patient
The tRNA molecule holding a growing polypeptide chain b. P site
is at the _ _.
a. E site
b. P site
c. 50S site
d. A site
