2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
Please check the examination details below before entering your candidate information
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel International Advanced Level
Tuesday 6 May 2025
Paper
Morning (Time: 1 hour 30 minutes)
reference WBI11/01
Biology
International Advanced Subsidiary / Advanced Level
UNIT 1: Molecules, Diet, Transport and Health
You must have: Total Marks
Scientific calculator, ruler, HB pencil
Instructions:
•• Fill
Use black ink or ball-point pen.
in the boxes at the top of this page with your name,
centre number and candidate number.
•• Answer all questions.
Answer the questions in the spaces provided
– there may be more space than you need.
•• Calculators may be used.
You must show all your working out with your answer clearly identified at the
end of your solution.
Information:
•• The total mark for this paper is 80.
The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each question.
• structure
In questions marked with an asterisk (*), marks will be awarded for your ability to
your answer logically, showing how the points you make are related or
follow on from each other where appropriate.
Advice:
• Read each question carefully before you start to answer it.
•• Checkanswer
Try to every question.
your answers if you have time at the end. Turn over
P78735A
©2025 Pearson Education Ltd.
Y:1/1/1/1/1/
*P78735A0128*
2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
,2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
BLANK PAGE
DO NOT WRITE IN THIS AREA
2
2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
*P78735A0228*
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
, 2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
Answer ALL questions. Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If you change your mind about an
DO NOT WRITE IN THIS AREA
answer, put a line through the box and then mark your new answer with a cross .
1: One risk factor for cardiovascular disease is a short blood clotting time.
One test for measuring blood clotting time is the prothrombin time (PT).
(a) Read through the following passage about prothrombin and the blood
clotting process.
Complete the passage by writing the most appropriate word or words on the
dotted lines.
(3)
Prothrombin is transported in the . . . . .. ... ... ... ... .. ... ... ... ... .. ... ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. of a human.
It is converted into thrombin by an enzyme called ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. ... ... ... ... ... .. ... ... ... ... .. ... ... ... .. .
The substrate for thrombin is . . . . . . . . . . . . . . . . .. .. ... ... ... ... .. ... ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. .
DO NOT WRITE IN THIS AREA
(b) Which pair of drugs is used to treat patients who have short blood clotting times?
(1)
A anticoagulants and antihypertensives
B anticoagulants and platelet inhibitors
C antihypertensives and statins
D platelet inhibitors and statins
(c) The range for a healthy PT is between 10 and 13 seconds.
A person with a PT of 8.5 seconds was treated with a drug to increase the PT time
to 10 seconds.
Calculate the percentage increase in PT from 8.5 seconds to 10 seconds.
(1)
DO NOT WRITE IN THIS AREA
Answer .. ... ... ... .. ... ... ... ... ... .. ... ... ... ... .. ... . . .. . .. . .. . .. . . %
(Total for Question 1 = 5 marks)
3
2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
*P78735A0328*
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
Turn over
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
Please check the examination details below before entering your candidate information
Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel International Advanced Level
Tuesday 6 May 2025
Paper
Morning (Time: 1 hour 30 minutes)
reference WBI11/01
Biology
International Advanced Subsidiary / Advanced Level
UNIT 1: Molecules, Diet, Transport and Health
You must have: Total Marks
Scientific calculator, ruler, HB pencil
Instructions:
•• Fill
Use black ink or ball-point pen.
in the boxes at the top of this page with your name,
centre number and candidate number.
•• Answer all questions.
Answer the questions in the spaces provided
– there may be more space than you need.
•• Calculators may be used.
You must show all your working out with your answer clearly identified at the
end of your solution.
Information:
•• The total mark for this paper is 80.
The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each question.
• structure
In questions marked with an asterisk (*), marks will be awarded for your ability to
your answer logically, showing how the points you make are related or
follow on from each other where appropriate.
Advice:
• Read each question carefully before you start to answer it.
•• Checkanswer
Try to every question.
your answers if you have time at the end. Turn over
P78735A
©2025 Pearson Education Ltd.
Y:1/1/1/1/1/
*P78735A0128*
2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
,2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
DO NOT WRITE IN THIS AREA
DO NOT WRITE IN THIS AREA
BLANK PAGE
DO NOT WRITE IN THIS AREA
2
2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
*P78735A0228*
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
, 2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
Answer ALL questions. Write your answers in the spaces provided.
Some questions must be answered with a cross in a box . If you change your mind about an
DO NOT WRITE IN THIS AREA
answer, put a line through the box and then mark your new answer with a cross .
1: One risk factor for cardiovascular disease is a short blood clotting time.
One test for measuring blood clotting time is the prothrombin time (PT).
(a) Read through the following passage about prothrombin and the blood
clotting process.
Complete the passage by writing the most appropriate word or words on the
dotted lines.
(3)
Prothrombin is transported in the . . . . .. ... ... ... ... .. ... ... ... ... .. ... ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. of a human.
It is converted into thrombin by an enzyme called ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. ... ... ... ... ... .. ... ... ... ... .. ... ... ... .. .
The substrate for thrombin is . . . . . . . . . . . . . . . . .. .. ... ... ... ... .. ... ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. ... ... ... ... .. .
DO NOT WRITE IN THIS AREA
(b) Which pair of drugs is used to treat patients who have short blood clotting times?
(1)
A anticoagulants and antihypertensives
B anticoagulants and platelet inhibitors
C antihypertensives and statins
D platelet inhibitors and statins
(c) The range for a healthy PT is between 10 and 13 seconds.
A person with a PT of 8.5 seconds was treated with a drug to increase the PT time
to 10 seconds.
Calculate the percentage increase in PT from 8.5 seconds to 10 seconds.
(1)
DO NOT WRITE IN THIS AREA
Answer .. ... ... ... .. ... ... ... ... ... .. ... ... ... ... .. ... . . .. . .. . .. . .. . . %
(Total for Question 1 = 5 marks)
3
2025 june2025
Pearson
june2025
Pearson
Edexcel
june International
Pearson
Edexcel International
Edexcel
Advanced
International
Advanced
Level Biology
Advanced
LevelUnit
*P78735A0328*
Biology
Level
1 WBI11
Unit
Biology
101WBI11
Molecules
Unit 101WBI11
Molecules
Diet01
Transport
Molecules
Diet Transport
andDiet
Health
Transport
and
QHealth
Paper.pdf
and
QHealth
Paper.pdf
Q Paper.pdf
Turn over
