NUR 3280 - MED ADMIN (PPT 2) QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED A+||BRAND NEW

NUR 3280 - MED ADMIN (PPT 2) QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS) |ALREADY
GRADED A+||BRAND NEW
PHARMACOKINETICS Ans✓✓✓ Transmission of medication through
body once administered.
What the body does to the drug.


PHARMACODYNAMICS Ans✓✓✓ How the drug acts on cells,
tissues, or receptors to produce therapeutic or adverse effects
WHAT THE DRUG DOES TO THE BODY


PHARMACOKINETICS DRUG PROCESSES (4) Ans✓✓✓ ADME:
ABSORPTION
DISTRIBUTION
METABOLISM
EXCRETION


ABSORPTION Ans✓✓✓ Transmission of medication from site of
administration to bloodstream


ABSORPTION INFLUENCED BY Ans✓✓✓ • Route of administration
(IV FASTEST / SUBQ>IM)
• Drug solubility & dissolution rate (FAT SOLUBLE DRUGS
FASTER)
• Perfusion (MORE PERFUSION = FASTER)

, • Body surface area / area of absorptive surface (HIGHER SA =
HIGHER ABSORPTION)


FIRST PASS EFFECT Ans✓✓✓ Hepatic metabolism of the drug IN
LIVER before it reaches the systemic circulation
BASICALLY MOST DRUG BROKEN DOWN IN LIVER FIRST
TIME TAKEN BEFORE DOING ITS THING
ONLY GI ROUTES (ORALLY)


Distribution Ans✓✓✓ DRUGS CARRIED BY BLOOD AND TISSUE
FLUIDS TO
ACTION SITES
METABOLISM SITES
EXCRETION SITES
DEPENDENT ON ADEQUACY OF BLOOD CIRC


DISTRIBUTION PROCESSES AFFECTED BY Ans✓✓✓ protein
binding (unbound meds to protein faster than bound to protein)
blood-brain barrier
pregnancy (placental barrier)


PEOPLE W LOW ALBUMIN (PROTEIN) NEED UNBOUND
MEDICATION TO DISTRIBUTE