CNUR 300 KEY REVISION ASSESSMENT TEST
2026 TESTED QUESTIONS WITH FULL
SOLUTION GRADED A+
◉ •Drugs need to be hydrophilic to be excreted in the Answer: urine
- This means that they need to be conjugated in the liver first as part
of second pass.
◉ •There are 4 types of receptors that drugs interact with? Answer:
•Ligand gated ion channels
•G protein coupled receptors
•Enzyme linked receptor
Intracellular receptor
◉ The receptor that the drug interacts with determines? Answer:
the action of the drug
◉ Pharmacologic effect: Answer: •The effect that a drug has on the
cell
• Effect increases with dose, until...
•Emax: Effect of the drug increases until all receptors are occupied
by the drug (see graph)
,•Cells can regulate the number of receptors that are on the cell
surface
◉ every time you give more BP medicine? Answer: the receptors
become saturated, so the effect will be smaller and smaller until the
full effect of the medicine is gone. That's why sometimes we must
approach more than 1 type of drugs to fix a problem.
◉ Agonist Answer: mimic biologic effect or potentiate effects - helps
very well with pain
◉ Partial Agonist Answer: -potentiates biological effect (but not as
strong as true agonist) - not perfect - but helps reduce pain with no
as much euphoria from narcan (in case someone wants to get clean)
◉ Inverse agonist Answer: binds to same receptor, but produces
opposite effect - pt would be in pain
◉ Antagonist Answer: competes for or blocks the agonist from
binding - NARCAN - blocks 100% of the receptors, so morphine or
any other med can't connect.
◉ What determines how a patient responds to a drug? Answer: - Age
- Gender
,- Ethnicity
- Genetic make-up
- Disease (severity, progression)
- Lifestyle
- Other drugs/ illnesses
◉ Pharmacogenetics Answer: the study of how genetic variation
affects an individual's response to drugs
◉ pharmacogenomics Answer: the study of how genetic inheritance
affects the body's response to drugs
◉ •Nursing responsibilities when administering drugs Answer:
•Name of drug and classification
•Intended use
•Effect on body
•Contraindications
•Special considerations
•Side effects
•Patient specific
•How supplied
•Administration and dosages
, •Nursing considerations
◉ •Three checks of drug administration Answer: •Check drug
•With medication information system (MAR)
•When preparing it, removing it from unit, or connecting IV
•Before administration (2 identifiers)
◉ IV Administration Answer: 100% bioavailability.
•Medications & Fluids
•Direct administration
•Total blood volume circulates approximately every minute
•IV push meds typically given over 60sec-5min (a lot of variance
here)
•Immediate use by body
•Rapid onset of action
•By avoiding GI tracta no first-pass effect of liver
◉ •Round to nearest 0.1 for medications, except when? Answer:
calculating a drip rate --> round to nearest whole number
•Calculations
◉ gtts Answer: drop, drops
2026 TESTED QUESTIONS WITH FULL
SOLUTION GRADED A+
◉ •Drugs need to be hydrophilic to be excreted in the Answer: urine
- This means that they need to be conjugated in the liver first as part
of second pass.
◉ •There are 4 types of receptors that drugs interact with? Answer:
•Ligand gated ion channels
•G protein coupled receptors
•Enzyme linked receptor
Intracellular receptor
◉ The receptor that the drug interacts with determines? Answer:
the action of the drug
◉ Pharmacologic effect: Answer: •The effect that a drug has on the
cell
• Effect increases with dose, until...
•Emax: Effect of the drug increases until all receptors are occupied
by the drug (see graph)
,•Cells can regulate the number of receptors that are on the cell
surface
◉ every time you give more BP medicine? Answer: the receptors
become saturated, so the effect will be smaller and smaller until the
full effect of the medicine is gone. That's why sometimes we must
approach more than 1 type of drugs to fix a problem.
◉ Agonist Answer: mimic biologic effect or potentiate effects - helps
very well with pain
◉ Partial Agonist Answer: -potentiates biological effect (but not as
strong as true agonist) - not perfect - but helps reduce pain with no
as much euphoria from narcan (in case someone wants to get clean)
◉ Inverse agonist Answer: binds to same receptor, but produces
opposite effect - pt would be in pain
◉ Antagonist Answer: competes for or blocks the agonist from
binding - NARCAN - blocks 100% of the receptors, so morphine or
any other med can't connect.
◉ What determines how a patient responds to a drug? Answer: - Age
- Gender
,- Ethnicity
- Genetic make-up
- Disease (severity, progression)
- Lifestyle
- Other drugs/ illnesses
◉ Pharmacogenetics Answer: the study of how genetic variation
affects an individual's response to drugs
◉ pharmacogenomics Answer: the study of how genetic inheritance
affects the body's response to drugs
◉ •Nursing responsibilities when administering drugs Answer:
•Name of drug and classification
•Intended use
•Effect on body
•Contraindications
•Special considerations
•Side effects
•Patient specific
•How supplied
•Administration and dosages
, •Nursing considerations
◉ •Three checks of drug administration Answer: •Check drug
•With medication information system (MAR)
•When preparing it, removing it from unit, or connecting IV
•Before administration (2 identifiers)
◉ IV Administration Answer: 100% bioavailability.
•Medications & Fluids
•Direct administration
•Total blood volume circulates approximately every minute
•IV push meds typically given over 60sec-5min (a lot of variance
here)
•Immediate use by body
•Rapid onset of action
•By avoiding GI tracta no first-pass effect of liver
◉ •Round to nearest 0.1 for medications, except when? Answer:
calculating a drip rate --> round to nearest whole number
•Calculations
◉ gtts Answer: drop, drops
