PCB 3233 Exam 2 Questions With Correct Answers
// // // // // // //
What //are //two //cells //that //use //receptors //to //distinguish //between //self //and //non-self //cells? //-
CORRECT //ANSWERS(S)✔✔-Macrophages
//
-NK //Cells
C3b //is //a //ligand //for //- //CORRECT //ANSWERS(S)✔✔Macrophage //CR1
CR3 //& //CR4 //- //CORRECT //ANSWERS(S)✔✔Recognize //iC3b //& //other //ligands //including //LPS
Lectins //- //CORRECT //ANSWERS(S)✔✔Carbohydrates-binding //proteins //
ex: //Mannose //& //glucose //receptors
Scavenger //Receptors //- //CORRECT //ANSWERS(S)✔✔Prefer //molecules //that //are //negatively
//charged //like //nucleic //acids, //LPS.
Phagocytic //Receptors //- //CORRECT //ANSWERS(S)✔✔Bind //directly //to //microbial //surface
//components
What //do //surface //receptors //promote? //- //CORRECT //ANSWERS(S)✔✔Phagocytosis
PRR's //bind //to //- //CORRECT //ANSWERS(S)✔✔PAMPs //on //pathogens
Receptors //that //detect //microbial //products //signal //what? //- //CORRECT //ANSWERS(S)✔✔-
Macrophage //activation
-Cytokine //Secretion
, Toll-Like //Receptors //(TLR) //- //CORRECT //ANSWERS(S)✔✔-10 //receptors
-Has //specificities //for //several //microbial //products
TLR-4 //- //CORRECT //ANSWERS(S)✔✔-Senses //LPS
-Found //on //macrophages
What //can //LPS //cause? //- //CORRECT //ANSWERS(S)✔✔Septic //Shock
What //is //LPS //known //for //being? //- //CORRECT //ANSWERS(S)✔✔Endotoxin
What //is //local //accumulation //of //fluid //accompanied //by? //- //CORRECT
ANSWERS(S)✔✔Swelling, //redness, //heat, //& //pain
//
What //does //increased //dilation //cause? //- //CORRECT //ANSWERS(S)✔✔Reduced //blood //flow
Complement //receptors //3&4 //(Mac-1, //CD11b, //CD8) //target //what? //- //CORRECT
ANSWERS(S)✔✔Bacteria //& //Fungi
//
CD14 //binds //to //what? //- //CORRECT //ANSWERS(S)✔✔-LPS
-Peptidoglycan
What //does //IL-8 //(CXCL-8) //do? //- //CORRECT //ANSWERS(S)✔✔Attracts //leukocytes //(neutrophils)
//to //the //site //of //infection/damage
What //are //your //proinflammatory //cytokines? //- //CORRECT //ANSWERS(S)✔✔-IL-1Beta
// // // // // // //
What //are //two //cells //that //use //receptors //to //distinguish //between //self //and //non-self //cells? //-
CORRECT //ANSWERS(S)✔✔-Macrophages
//
-NK //Cells
C3b //is //a //ligand //for //- //CORRECT //ANSWERS(S)✔✔Macrophage //CR1
CR3 //& //CR4 //- //CORRECT //ANSWERS(S)✔✔Recognize //iC3b //& //other //ligands //including //LPS
Lectins //- //CORRECT //ANSWERS(S)✔✔Carbohydrates-binding //proteins //
ex: //Mannose //& //glucose //receptors
Scavenger //Receptors //- //CORRECT //ANSWERS(S)✔✔Prefer //molecules //that //are //negatively
//charged //like //nucleic //acids, //LPS.
Phagocytic //Receptors //- //CORRECT //ANSWERS(S)✔✔Bind //directly //to //microbial //surface
//components
What //do //surface //receptors //promote? //- //CORRECT //ANSWERS(S)✔✔Phagocytosis
PRR's //bind //to //- //CORRECT //ANSWERS(S)✔✔PAMPs //on //pathogens
Receptors //that //detect //microbial //products //signal //what? //- //CORRECT //ANSWERS(S)✔✔-
Macrophage //activation
-Cytokine //Secretion
, Toll-Like //Receptors //(TLR) //- //CORRECT //ANSWERS(S)✔✔-10 //receptors
-Has //specificities //for //several //microbial //products
TLR-4 //- //CORRECT //ANSWERS(S)✔✔-Senses //LPS
-Found //on //macrophages
What //can //LPS //cause? //- //CORRECT //ANSWERS(S)✔✔Septic //Shock
What //is //LPS //known //for //being? //- //CORRECT //ANSWERS(S)✔✔Endotoxin
What //is //local //accumulation //of //fluid //accompanied //by? //- //CORRECT
ANSWERS(S)✔✔Swelling, //redness, //heat, //& //pain
//
What //does //increased //dilation //cause? //- //CORRECT //ANSWERS(S)✔✔Reduced //blood //flow
Complement //receptors //3&4 //(Mac-1, //CD11b, //CD8) //target //what? //- //CORRECT
ANSWERS(S)✔✔Bacteria //& //Fungi
//
CD14 //binds //to //what? //- //CORRECT //ANSWERS(S)✔✔-LPS
-Peptidoglycan
What //does //IL-8 //(CXCL-8) //do? //- //CORRECT //ANSWERS(S)✔✔Attracts //leukocytes //(neutrophils)
//to //the //site //of //infection/damage
What //are //your //proinflammatory //cytokines? //- //CORRECT //ANSWERS(S)✔✔-IL-1Beta
