PCB 3233 IMMUNOLOGY - EXAM 3 QUESTIONS WITH CORRECT ANSWERS

PCB 3233 IMMUNOLOGY - EXAM 3 QUESTIONS WITH
// // // // // // //




CORRECT ANSWERS
// // //




Which //cell //types //can //become //a //plasma //cell? //- //CORRECT //ANSWERS(S)✔✔All //the //above
//(a //memory //B-cell, //an //activated //B-cell, //a //centrocyte




The //types //of //human //MHC //II //presenting //molecules //are: //- //CORRECT //ANSWERS(S)✔✔HLA-
DP, //HLA-DQ, //HLA-DR //which //present //peptide //to //CD4 //T-cells



__________ //has //an //alpha //chain //and //a //beta //chain //in //their //structure //while //________
only //has //an //alpha //chain //in //its //structure? //- //CORRECT //ANSWERS(S)✔✔MHC //II, //MHC //I
//




What //process(es) //are //used //after //activation //to //make //MHC //I //and //II //binding //sites //better? //-
//CORRECT //ANSWERS(S)✔✔None //of //the //above //(Somatic //recombination, //somatic
//hypermutation, //isotype //switching




Burkitt's //lymphoma //is //due //to //a //translocation //of //the //________ //gene //next //of //one //of //the
________ //genes. //- //CORRECT //ANSWERS(S)✔✔MYC, //Ig
//




You //would //expect //the //IgA //and //IgB //genes //to //be //turned //on //(expressed) //during //which
//stage/s? //- //CORRECT //ANSWERS(S)✔✔All //the //above //(the //small //pre //B //cell, //mature //B //cell,
//immature //B //cell




T-cell //receptor //diversity //is //established //- //CORRECT //ANSWERS(S)✔✔Before //antigen
//stimulation




The //types //of //human //MHC //I //presenting //molecules //are: //- //CORRECT //ANSWERS(S)✔✔HLA-A,
//HLA-B //and //HLA-C //which //present //peptide //to //CD8 //T-cells

, Receptor //editing //- //CORRECT //ANSWERS(S)✔✔A //& //B //(is //done //on //the //light //chain, //can //be
//utilized //in //an //attempt //to //rescue //a //B-cell //that //has //a //self-reactive //receptor




Which //one //of //the //following //is //in //the //correct //sequence? //- //CORRECT //ANSWERS(S)✔✔Early
//Pro-B, //Late //Pro-B, //Large //Pre-B, //Small //Pre-B, //Immature //B-cell




When/where //are //N //and //P //nucleotide //additions //added //to //the //variable //regions //(binding
site? //- //CORRECT //ANSWERS(S)✔✔During //somatic //recombination
//




Which //chemokine/s //call/s //a //B-cell //into //the //follicle //of //a //secondary //lymphoid //tissue? //-
CORRECT //ANSWERS(S)✔✔CXCL //13
//




Which //cell/s //is/are //lymphocyte/s? //- //CORRECT //ANSWERS(S)✔✔None //of //the //above
//(neutrophils, //macrophages, //dendritic //cells




Which //of //the //following //is/are //considered //proto-oncogenes? //- //CORRECT //ANSWERS(S)✔✔A
//& //B //(BCL2, //MYC)




A //mature //B-cell //has: //- //CORRECT //ANSWERS(S)✔✔IgM, //IgD //and //IgA //and //IgB //on //the
//surface




True //of //false: //CCL19 //and //CCL21 //direct //a //B-cell //out //of //the //blood //stream, //across //HEV's
//and //into //a //secondary //lymphocyte //toward //the //T-cell //era. //- //CORRECT


ANSWERS(S)✔✔True
//




The //peptide-binding //groove //of //an //MHC //class //I //molecule //is //composed //of //the //following
extracelllular //dendritic //cells? //- //CORRECT //ANSWERS(S)✔✔a1 //: //a2
//