PCB 3233 - Final Exam Questions With Correct Answers
// // // // // // // // //
What //are //the //primary //adaptive //immune //cells? //- //CORRECT //ANSWERS(S)✔✔B //and //T //cells
What //cells //are //lymphocytes? //- //CORRECT //ANSWERS(S)✔✔NK, //B, //and //T //cells
What //does //the //red //pulp //of //the //spleen //do? //- //CORRECT //ANSWERS(S)✔✔erythrocyte //(RBC)
//filtration
What //does //the //white //pulp //of //the //spleen //do? //- //CORRECT //ANSWERS(S)✔✔leukocyte
//(WBC) //filtration
inactivation //by //Factor //H //and //I //results //in //an //opsonin //
-NOT //a //convertase
this //is //what //C //- //CORRECT //ANSWERS(S)✔✔ic3b
DAF //stands //for //- //CORRECT //ANSWERS(S)✔✔decay //accelerating //factor
MCP //stands //for //- //CORRECT //ANSWERS(S)✔✔membrane //cofactor //protein
inhibit //the //activity //of //bacterial //proteases //- //CORRECT //ANSWERS(S)✔✔alpha2-
macroglobulins
,are //the //human //version //of //MAC //complex, //which //creates //pores/holes //in //pathogenic
surfaces //- //CORRECT //ANSWERS(S)✔✔defensins
//
What //cell //makes //up //the //highest //concentration //of //leukocytes? //- //CORRECT
ANSWERS(S)✔✔neutrophils
//
pus //forming //- //CORRECT //ANSWERS(S)✔✔pyogenic
fever //inducing //pyogenic //or //pyrogenic //- //CORRECT //ANSWERS(S)✔✔pyrogenic
CR1 //binds //to //- //CORRECT //ANSWERS(S)✔✔C3b
CR2 //binds //to //- //CORRECT //ANSWERS(S)✔✔C3d
CR3 //binds //to //- //CORRECT //ANSWERS(S)✔✔iC3b
CR4 //binds //to //what //on //G //bacteria //- //CORRECT //ANSWERS(S)✔✔LPS //on //G- //bacteria
TLR-3 //binds //to //what //virsus //- //CORRECT //ANSWERS(S)✔✔dsRNA //viruses
TLR-4 //binds //to //what //on //bacteria //- //CORRECT //ANSWERS(S)✔✔LPS //on //G- //bacteria
TLR-5 //binds //to //- //CORRECT //ANSWERS(S)✔✔Flagellin
TLR-7 //binds //to //virsus //- //CORRECT //ANSWERS(S)✔✔ssRNA //viruses
,recognize //bacterial //cell //components //2 //N //- //CORRECT //ANSWERS(S)✔✔NOD-1/NOD-2
a //form //of //cytokine //that //directs //leukocyte //traff //- //CORRECT //ANSWERS(S)✔✔chemokines
cytokines
proinflammotory //
IL-1,2,3,4,5,6,7,8,9,10,11,12, //CX, //and //T
name //the //5 //hint:IL-1 //- //CORRECT //ANSWERS(S)✔✔proinflammatory //mediators //( //IL-1, //IL-6,
//IL-12, //CXCL8, //and //TNF-alpha)
What //cells //are //NOT //in //germline //configuration? //- //CORRECT //ANSWERS(S)✔✔mature //B //and
//mature //T //cells
-first //Ab //produced //- //CORRECT //ANSWERS(S)✔✔IgM
Pentameric //- //CORRECT //ANSWERS(S)✔✔IgM
activateis //complement
which //IG //? //2 //- //CORRECT //ANSWERS(S)✔✔Igm //IgG
can //cross //mucosal //cell //via //polyg //Ig //recepor //- //CORRECT //ANSWERS(S)✔✔IgM //and //dimeric
//IgA
-highest //concentration //in //blood //- //CORRECT //ANSWERS(S)✔✔IgG
, -good //for //neutralization/opsonization //- //CORRECT //ANSWERS(S)✔✔IgG
crosses //placenta //via //the //FcRn/FcRB/Brambell //receptor //- //CORRECT //ANSWERS(S)✔✔IgG
can //be //monomeric //or //dimeric
where //are //they //found? //- //CORRECT //ANSWERS(S)✔✔IgA
monomeric=circulation
dimeric=gut
-most //abundant //in //the //body
which //Ig //- //CORRECT //ANSWERS(S)✔✔IgA
-involved //in //allergic //reactions //and //parasites //- //CORRECT //ANSWERS(S)✔✔IgE
-present //in //serum //in //low //levels: //IgG,A,M,E //- //CORRECT //ANSWERS(S)✔✔IgE
high //affinity //for //FCeRII //found //on //mast //cells, //basophils, //and //activated //eosinophils //-
CORRECT //ANSWERS(S)✔✔IgE
//
-found //on //the //surface //of //mature, //naive //B //cells //(along //with //IgM) //- //CORRECT
ANSWERS(S)✔✔IgD
//
// // // // // // // // //
What //are //the //primary //adaptive //immune //cells? //- //CORRECT //ANSWERS(S)✔✔B //and //T //cells
What //cells //are //lymphocytes? //- //CORRECT //ANSWERS(S)✔✔NK, //B, //and //T //cells
What //does //the //red //pulp //of //the //spleen //do? //- //CORRECT //ANSWERS(S)✔✔erythrocyte //(RBC)
//filtration
What //does //the //white //pulp //of //the //spleen //do? //- //CORRECT //ANSWERS(S)✔✔leukocyte
//(WBC) //filtration
inactivation //by //Factor //H //and //I //results //in //an //opsonin //
-NOT //a //convertase
this //is //what //C //- //CORRECT //ANSWERS(S)✔✔ic3b
DAF //stands //for //- //CORRECT //ANSWERS(S)✔✔decay //accelerating //factor
MCP //stands //for //- //CORRECT //ANSWERS(S)✔✔membrane //cofactor //protein
inhibit //the //activity //of //bacterial //proteases //- //CORRECT //ANSWERS(S)✔✔alpha2-
macroglobulins
,are //the //human //version //of //MAC //complex, //which //creates //pores/holes //in //pathogenic
surfaces //- //CORRECT //ANSWERS(S)✔✔defensins
//
What //cell //makes //up //the //highest //concentration //of //leukocytes? //- //CORRECT
ANSWERS(S)✔✔neutrophils
//
pus //forming //- //CORRECT //ANSWERS(S)✔✔pyogenic
fever //inducing //pyogenic //or //pyrogenic //- //CORRECT //ANSWERS(S)✔✔pyrogenic
CR1 //binds //to //- //CORRECT //ANSWERS(S)✔✔C3b
CR2 //binds //to //- //CORRECT //ANSWERS(S)✔✔C3d
CR3 //binds //to //- //CORRECT //ANSWERS(S)✔✔iC3b
CR4 //binds //to //what //on //G //bacteria //- //CORRECT //ANSWERS(S)✔✔LPS //on //G- //bacteria
TLR-3 //binds //to //what //virsus //- //CORRECT //ANSWERS(S)✔✔dsRNA //viruses
TLR-4 //binds //to //what //on //bacteria //- //CORRECT //ANSWERS(S)✔✔LPS //on //G- //bacteria
TLR-5 //binds //to //- //CORRECT //ANSWERS(S)✔✔Flagellin
TLR-7 //binds //to //virsus //- //CORRECT //ANSWERS(S)✔✔ssRNA //viruses
,recognize //bacterial //cell //components //2 //N //- //CORRECT //ANSWERS(S)✔✔NOD-1/NOD-2
a //form //of //cytokine //that //directs //leukocyte //traff //- //CORRECT //ANSWERS(S)✔✔chemokines
cytokines
proinflammotory //
IL-1,2,3,4,5,6,7,8,9,10,11,12, //CX, //and //T
name //the //5 //hint:IL-1 //- //CORRECT //ANSWERS(S)✔✔proinflammatory //mediators //( //IL-1, //IL-6,
//IL-12, //CXCL8, //and //TNF-alpha)
What //cells //are //NOT //in //germline //configuration? //- //CORRECT //ANSWERS(S)✔✔mature //B //and
//mature //T //cells
-first //Ab //produced //- //CORRECT //ANSWERS(S)✔✔IgM
Pentameric //- //CORRECT //ANSWERS(S)✔✔IgM
activateis //complement
which //IG //? //2 //- //CORRECT //ANSWERS(S)✔✔Igm //IgG
can //cross //mucosal //cell //via //polyg //Ig //recepor //- //CORRECT //ANSWERS(S)✔✔IgM //and //dimeric
//IgA
-highest //concentration //in //blood //- //CORRECT //ANSWERS(S)✔✔IgG
, -good //for //neutralization/opsonization //- //CORRECT //ANSWERS(S)✔✔IgG
crosses //placenta //via //the //FcRn/FcRB/Brambell //receptor //- //CORRECT //ANSWERS(S)✔✔IgG
can //be //monomeric //or //dimeric
where //are //they //found? //- //CORRECT //ANSWERS(S)✔✔IgA
monomeric=circulation
dimeric=gut
-most //abundant //in //the //body
which //Ig //- //CORRECT //ANSWERS(S)✔✔IgA
-involved //in //allergic //reactions //and //parasites //- //CORRECT //ANSWERS(S)✔✔IgE
-present //in //serum //in //low //levels: //IgG,A,M,E //- //CORRECT //ANSWERS(S)✔✔IgE
high //affinity //for //FCeRII //found //on //mast //cells, //basophils, //and //activated //eosinophils //-
CORRECT //ANSWERS(S)✔✔IgE
//
-found //on //the //surface //of //mature, //naive //B //cells //(along //with //IgM) //- //CORRECT
ANSWERS(S)✔✔IgD
//