Maryville Pharm Exam 3 Questions and Correct Answers 2026/2027

Maryville Pharm Exam 3 Questions and Correct Answers 2026/2027 Colchicine use - Correct Answer Reduce incidence of acute gout attacks relieves pain and discomfort (although it is not an analgesic) Colchicine Actions - Correct Answer inhibits migration of granulocytes to the inflamed areas Reduces lactic acid production by granulocytes decreases deposition of uric acid interferes with kinin formation and reduces phagocytosis Overall effect is it decreases the inflammatory response to urate crystals Colchicine cautions - Correct Answer Renal Failure- not effective in the presence of renal failure. Poorly excreted with RF. Hepatic dysfunction- associated with hepatotoxicity Peptic ulcer disease or spastic colon- will worsen GI disturbances Colchicine Adverse Effects - Correct Answer Nausea, vomiting, diarrhea, and abdominal pain Malabsorption of vitamin B12 Elevated levels with RF may lead to myopathy, neuropathy, & muscle weakness