Pharm 1141 Exam 2
Pharm 1141 Exam 2 2026 Latest Updated
Questions With Answers Success Guide.
What is the mechanism of action for beta blockers? -
Correct Answer -block beta receptors, which prevents
naturally occurring catecholamines from stimulating. thus
heart rate, cardiac output, and bp are reduced.
also inhibit renin release, thus RAAS is reduced, lowering
hypertension
What does RAAS do? -
Correct Answer -A hormone system that regulates blood
pressure and water (fluid) balance.
When blood volume is low, juxtaglomerular cells in the
kidneys secrete renin directly into circulation. Plasma renin
then carries out the conversion of angiotensinogen
released by the liver to angiotensin I. Angiotensin I is
subsequently converted to angiotensin II by ACE found in
the lungs. Angiotensin II is a potent vaso-active peptide
that causes blood vessels to constrict, resulting in
increased blood pressure. Angiotensin II also stimulates
the secretion of the hormone aldosterone from the adrenal
cortex. Aldosterone causes the tubules of the kidneys to
increase the reabsorption of sodium and water into the
blood. This increases the volume of fluid in the body,
which also increases blood pressure.
What are beta blockers (BBs) used for? -
Correct Answer ---> used extensively to treat post-MI
also used for:
-hypertension
-angina pectoris
-cardiac dysrhythmias
-symptoms of hyperthyroidism
1
, Pharm 1141 Exam 2
-stage fright.
What are some contraindications of BBs? -
Correct Answer ---use WITH caution in patients w/
diabetes and/or with those who are susceptible to
hypoglycemia ((BB mask the signs and symptoms of
hypoglycemia))
--NOT as effective in african americans
--NOT for pts with asthma, uncontrolled heart failure, heart
failure caused by systolic dysfunction, and peripheral
vascular disease
What is the difference between selective and nonselective
beta blockers? -
Correct Answer -Nonselective agents have an equal
affinity for beta-1 and beta-2 receptors, and they inhibit
both.
Selective agents exhibit action against the heart's beta-1
receptors (cardioselective) and do not readily affect the
beta-2 receptors of the bronchi.
What is an important patient education aspect about BBs?
-
Correct Answer -to avoid rapid discontinuation of drug,
and rather a controlled, slow decline over a couple of
weeks
What are 3 SELECTIVE BBs? -
Correct Answer -1. atenolol (Tenormin)
2. esmolol (Brevibloc)
3. metoprolol (Lopressor)
What is metoprolol (Lopressor) used for? -
Correct Answer -HTN, angina, MI, heart failure
2
Pharm 1141 Exam 2 2026 Latest Updated
Questions With Answers Success Guide.
What is the mechanism of action for beta blockers? -
Correct Answer -block beta receptors, which prevents
naturally occurring catecholamines from stimulating. thus
heart rate, cardiac output, and bp are reduced.
also inhibit renin release, thus RAAS is reduced, lowering
hypertension
What does RAAS do? -
Correct Answer -A hormone system that regulates blood
pressure and water (fluid) balance.
When blood volume is low, juxtaglomerular cells in the
kidneys secrete renin directly into circulation. Plasma renin
then carries out the conversion of angiotensinogen
released by the liver to angiotensin I. Angiotensin I is
subsequently converted to angiotensin II by ACE found in
the lungs. Angiotensin II is a potent vaso-active peptide
that causes blood vessels to constrict, resulting in
increased blood pressure. Angiotensin II also stimulates
the secretion of the hormone aldosterone from the adrenal
cortex. Aldosterone causes the tubules of the kidneys to
increase the reabsorption of sodium and water into the
blood. This increases the volume of fluid in the body,
which also increases blood pressure.
What are beta blockers (BBs) used for? -
Correct Answer ---> used extensively to treat post-MI
also used for:
-hypertension
-angina pectoris
-cardiac dysrhythmias
-symptoms of hyperthyroidism
1
, Pharm 1141 Exam 2
-stage fright.
What are some contraindications of BBs? -
Correct Answer ---use WITH caution in patients w/
diabetes and/or with those who are susceptible to
hypoglycemia ((BB mask the signs and symptoms of
hypoglycemia))
--NOT as effective in african americans
--NOT for pts with asthma, uncontrolled heart failure, heart
failure caused by systolic dysfunction, and peripheral
vascular disease
What is the difference between selective and nonselective
beta blockers? -
Correct Answer -Nonselective agents have an equal
affinity for beta-1 and beta-2 receptors, and they inhibit
both.
Selective agents exhibit action against the heart's beta-1
receptors (cardioselective) and do not readily affect the
beta-2 receptors of the bronchi.
What is an important patient education aspect about BBs?
-
Correct Answer -to avoid rapid discontinuation of drug,
and rather a controlled, slow decline over a couple of
weeks
What are 3 SELECTIVE BBs? -
Correct Answer -1. atenolol (Tenormin)
2. esmolol (Brevibloc)
3. metoprolol (Lopressor)
What is metoprolol (Lopressor) used for? -
Correct Answer -HTN, angina, MI, heart failure
2
