NURS 1141 PHARM EXAM 1 QUESTIONS AND
CORRECT ANSWERS (VERIFIED ANSWERS) PLUS
RATIONALES Q & A 2026|INSTANT DOWNLOAD
PDF
1. Which of the following are common routes of drug
administration?
A. Oral
B. Intravenous
C. Topical
D. Telepathic
Answer: A, B, C
Rationale: Drugs can be administered orally, intravenously, or
topically. Telepathic administration is not a medical method.
2. What are the phases of pharmacokinetics?
A. Absorption
B. Distribution
C. Metabolism
D. Excretion
Answer: A, B, C, D
Rationale: Pharmacokinetics involves ADME – absorption,
distribution, metabolism, and excretion of drugs.
,3. Which factors can affect drug absorption?
A. Food in the stomach
B. pH of the stomach
C. Blood flow to absorption site
D. Patient’s favorite color
Answer: A, B, C
Rationale: Food, stomach pH, and blood flow affect drug
absorption; favorite color is irrelevant.
4. What is the first-pass effect?
A. Drug metabolized in the liver before reaching systemic
circulation
B. Drug bypasses liver metabolism
C. Drug excreted via kidneys before absorption
D. Drug action in the brain only
Answer: A
Rationale: The first-pass effect occurs when orally administered
drugs are metabolized by the liver before systemic circulation.
5. Which of the following are types of drug interactions?
A. Synergistic
B. Antagonistic
,C. Additive
D. Psychic
Answer: A, B, C
Rationale: Drugs can interact synergistically, antagonistically, or
additively. "Psychic" is not a pharmacologic interaction.
6. Which of these drugs are considered beta-blockers?
A. Atenolol
B. Metoprolol
C. Propranolol
D. Furosemide
Answer: A, B, C
Rationale: Atenolol, Metoprolol, and Propranolol are beta-
blockers; Furosemide is a loop diuretic.
7. What are the primary nursing responsibilities in medication
administration?
A. Right patient
B. Right drug
C. Right dose
D. Right time
Answer: A, B, C, D
Rationale: Nurses follow the “Five Rights” (also including route
and documentation) to ensure safe medication administration.
, 8. Which medications require monitoring for nephrotoxicity?
A. Aminoglycosides
B. NSAIDs
C. ACE inhibitors
D. Acetaminophen
Answer: A, B, C
Rationale: Aminoglycosides, NSAIDs, and ACE inhibitors can be
nephrotoxic. Acetaminophen is mainly hepatotoxic.
9. What is the primary site of drug metabolism?
A. Liver
B. Kidneys
C. Stomach
D. Lungs
Answer: A
Rationale: The liver metabolizes most drugs through enzymatic
processes.
10. Which of the following are signs of an allergic reaction to a
medication?
A. Rash
B. Swelling
CORRECT ANSWERS (VERIFIED ANSWERS) PLUS
RATIONALES Q & A 2026|INSTANT DOWNLOAD
1. Which of the following are common routes of drug
administration?
A. Oral
B. Intravenous
C. Topical
D. Telepathic
Answer: A, B, C
Rationale: Drugs can be administered orally, intravenously, or
topically. Telepathic administration is not a medical method.
2. What are the phases of pharmacokinetics?
A. Absorption
B. Distribution
C. Metabolism
D. Excretion
Answer: A, B, C, D
Rationale: Pharmacokinetics involves ADME – absorption,
distribution, metabolism, and excretion of drugs.
,3. Which factors can affect drug absorption?
A. Food in the stomach
B. pH of the stomach
C. Blood flow to absorption site
D. Patient’s favorite color
Answer: A, B, C
Rationale: Food, stomach pH, and blood flow affect drug
absorption; favorite color is irrelevant.
4. What is the first-pass effect?
A. Drug metabolized in the liver before reaching systemic
circulation
B. Drug bypasses liver metabolism
C. Drug excreted via kidneys before absorption
D. Drug action in the brain only
Answer: A
Rationale: The first-pass effect occurs when orally administered
drugs are metabolized by the liver before systemic circulation.
5. Which of the following are types of drug interactions?
A. Synergistic
B. Antagonistic
,C. Additive
D. Psychic
Answer: A, B, C
Rationale: Drugs can interact synergistically, antagonistically, or
additively. "Psychic" is not a pharmacologic interaction.
6. Which of these drugs are considered beta-blockers?
A. Atenolol
B. Metoprolol
C. Propranolol
D. Furosemide
Answer: A, B, C
Rationale: Atenolol, Metoprolol, and Propranolol are beta-
blockers; Furosemide is a loop diuretic.
7. What are the primary nursing responsibilities in medication
administration?
A. Right patient
B. Right drug
C. Right dose
D. Right time
Answer: A, B, C, D
Rationale: Nurses follow the “Five Rights” (also including route
and documentation) to ensure safe medication administration.
, 8. Which medications require monitoring for nephrotoxicity?
A. Aminoglycosides
B. NSAIDs
C. ACE inhibitors
D. Acetaminophen
Answer: A, B, C
Rationale: Aminoglycosides, NSAIDs, and ACE inhibitors can be
nephrotoxic. Acetaminophen is mainly hepatotoxic.
9. What is the primary site of drug metabolism?
A. Liver
B. Kidneys
C. Stomach
D. Lungs
Answer: A
Rationale: The liver metabolizes most drugs through enzymatic
processes.
10. Which of the following are signs of an allergic reaction to a
medication?
A. Rash
B. Swelling
