QUESTIONS AND SOLUTIONS
◉Atomoxetine (Strattera). Answer: - BBW
> Risk of suicidal ideation; monitor for suicidal thinking or behavior,
worsening, or unusual behavior
- Contraindications
> Glaucoma, pheochromocytoma, MAO I use within past 14 days
- Warning
> Rare, but severe hepatotoxicity (most within 120 days of start of
treatment)
SE
> Headache, insomnia, *somnolence*, dry mouth, nausea, abdominal
pain, decrease in appetite, nausea, etc.
> Priapism
NOTE
> * do not open capsule * - irritant
> CYPD 2D6 substrate
> watch out for *LIVER PROBLEMS *
◉Clonidine Hydrochloride. Answer: Catapres, Catapres TTS, Kapvay
(Antihypertensive)
,◉Dexmethylphenidate Hydrochloride. Answer: Focalin; Focalin XR
Tablet,
capsule
CNS Stimulant
ADHD
◉Guanfacine Hydrochloride. Answer: Tenex, Intuniv
Antihypertensive/Antipsychotic
◉Lisdexamfetamine. Answer: Vyvanse
(ADHD, binge eating disorder)
◉Methylphenidate. Answer: Concerta, Ritalin, Metadate, Methylin
CNS Agent for ADHD Yes
◉methylphenidate hydrocholoride. Answer: Methylphenidate
Common brand names: Ritalin, Daytrana
This medication is used to treat attention deficit hyperactivity
disorder - ADHD.
Brand names: Ritalin · Daytrana · Metadate ER · Methylin · Quillivant
XR
Drug classes: Central Nervous System Stimulant · CNS Stimulant
,◉Dissociative disorders. Answer: =A group of disorders that cause
an impaired awareness of your own actions, thoughts, physical
sensations, and even identity, which is a sense of who you are.
◉Dissociative disorders. Answer: Divided into three main types:
depersonalization/derealization disorder, dissociative amnesia, and
dissociative identity disorder.
◉Dissociative disorders. Answer: Each of these disorders fall along a
spectrum of severity:
-depersonalization/derealization= the least severe of the
dissociative disorders,
-dissociative amnesia= somewhere in the middle of least severe and
severe,
-dissociative identity disorder= the most severe.
◉Depersonalization/derealization. Answer: -Might speak in a
deadpan manner, with little emotion, and have trouble forming
relationships.
-In severe cases, a person may have trouble recognizing familiar
places, people, or objects, and this can make it had to learn tasks.
◉Caprylidene. Answer: Medical food approved by FDA for treatment
of (AD)
, Axona
◉Aducanumab. Answer: - Alzheimer's drug
- decreases amyloid plaques
◉Donepezil (Aricept). Answer: *acetylcholinesterase inhibitor* -
inactivates enzyme that breaks down acetylcholine - which increases
available acetylcholine - which slows progression of AD;
*SIDE EFFECTS*: think parasympathetic activation - bradycardia,
hypotension, urination, defecation, GI upset, salivation, sweating
◉Galantamine. Answer: Reminyl ER
Cholinesterase Inhibitor
Dementia
◉Memantine (Namenda). Answer: NMDA receptor antagonist
- Alzheimer's /disease
◉Rivastigmine. Answer: • Acetylcholinesterase inhibitor
• Used to tx Alzheimer's
• Increases amount of ACh in presynaptic terminals
• Orally available