NR546/ NR 546 Study Guide
Week 1 to Week 4
Advanced Pharṃacology Psychopharṃacology
for the Psychiatric-Ṃental Health Nurse Practitioner
The Ultiṃate Study Guide to Pass Your Exaṃ
Inside, you'll get:
➢ Key areas to focus on in your NR 546 study guide:
➢ Review course:
➢ Review notes:
➢Practice questions with answers:
➢Case studies:
➢key terṃs and definitions:
, NR 546 MIDTERM EXAM
1. How does reviewing the genetic makeup of a client help guide the
PMHNP in selecting medication for clients
Answer> -Genetic testing can assist by providing more information on how
clients may respond to certain psychotropic medications
-provides information on how a client may break down and metabolize
medications based on the cytochrome P450 system.
2. Tanr1kulu and Erba_ (2020) investigated identical twins to determine
the presence of an inherited link for schizophrenia and why one twin may
develop schizophrenia when the other does not. When two people have
100% identical DNA, why don't both persons develop the exact illnesses?
Studies of identical Danish twins found that if one twin had
schizophrenia, the other twin had a 50% lifetime risk of developing
schizophrenia (Lemvigh et al., 2020). Why is there only half the risk
Answer> Both environmental and psychosocial stressors can im- pact
,mental health. Although twins may have identical genes, their gene
expression may be different.
There may be an environmental exposure that turned a gene "on" that
should have been "off" for one twin to develop schizophrenia and not the
other.
3. The field of epigenetics is rapidly growing and can help explain
how gene expression is
Answer> influenced by environmental factors and how epigenetics
contributes to the manifestation of mental illness
4. How does epigenetics impact a person's mental health
Answer> internal or external factors activate portions of the genome that
result in the manifestation of mental health symptoms
-activation is often a result of a stressful event, which, when combined with
the genetic risk, results in the disease
, -genes being on or off
-occurrence of symptoms may be the result of inheritance of an abnormal
gene or of normal genes being "on" when they should be "off."
5. Types of epigenetic changes
Answer> DNA Methylation Histone modification
Non-coding RNA
6. The potential legal and ethical issues impacting mental health
treatment must also be taken into account, including
Answer> -informed consent
-competence to make healthcare decisions
-off-label prescribing
7. What should the PMHNP consider when prescribing chemical restraints
Answer> -
Week 1 to Week 4
Advanced Pharṃacology Psychopharṃacology
for the Psychiatric-Ṃental Health Nurse Practitioner
The Ultiṃate Study Guide to Pass Your Exaṃ
Inside, you'll get:
➢ Key areas to focus on in your NR 546 study guide:
➢ Review course:
➢ Review notes:
➢Practice questions with answers:
➢Case studies:
➢key terṃs and definitions:
, NR 546 MIDTERM EXAM
1. How does reviewing the genetic makeup of a client help guide the
PMHNP in selecting medication for clients
Answer> -Genetic testing can assist by providing more information on how
clients may respond to certain psychotropic medications
-provides information on how a client may break down and metabolize
medications based on the cytochrome P450 system.
2. Tanr1kulu and Erba_ (2020) investigated identical twins to determine
the presence of an inherited link for schizophrenia and why one twin may
develop schizophrenia when the other does not. When two people have
100% identical DNA, why don't both persons develop the exact illnesses?
Studies of identical Danish twins found that if one twin had
schizophrenia, the other twin had a 50% lifetime risk of developing
schizophrenia (Lemvigh et al., 2020). Why is there only half the risk
Answer> Both environmental and psychosocial stressors can im- pact
,mental health. Although twins may have identical genes, their gene
expression may be different.
There may be an environmental exposure that turned a gene "on" that
should have been "off" for one twin to develop schizophrenia and not the
other.
3. The field of epigenetics is rapidly growing and can help explain
how gene expression is
Answer> influenced by environmental factors and how epigenetics
contributes to the manifestation of mental illness
4. How does epigenetics impact a person's mental health
Answer> internal or external factors activate portions of the genome that
result in the manifestation of mental health symptoms
-activation is often a result of a stressful event, which, when combined with
the genetic risk, results in the disease
, -genes being on or off
-occurrence of symptoms may be the result of inheritance of an abnormal
gene or of normal genes being "on" when they should be "off."
5. Types of epigenetic changes
Answer> DNA Methylation Histone modification
Non-coding RNA
6. The potential legal and ethical issues impacting mental health
treatment must also be taken into account, including
Answer> -informed consent
-competence to make healthcare decisions
-off-label prescribing
7. What should the PMHNP consider when prescribing chemical restraints
Answer> -
