ME AICE2 Oruc A.O.M
Complete Study Guide and
Exam Questions 2026 2027
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, ME AICE2 Oruc A.O.M 2026-03-05
What was the aim of the study?
to determine whether specific polymorphisms of two genes associated with
Serotonin transmission (5-HT2c and the 5-HTT gene) were more common
in people with bipolar disorder
What percentage of bipolar disorder's causes is attributed to genetic factors?
Up to 80%.
What challenges exist in identifying specific genes responsible for bipolar
disorder?
Complex inheritance patterns and difficulties in precise diagnoses.
What neurotransmitter is primarily investigated in relation to bipolar
disorder?
Serotonin.
What was the sample size of the study conducted by Oruč et al.?
> All Croatian
> 25 females and 17 males aged 31-70 with bipolar disorder (type 1)
>average age 32
> Medical records showed 16 of the Ps had at least 1 first-degree relative
with a mood disorder
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