Nagelhout Pharm 2 Test 2 EXAM (2025) QUESTIONS AND (elaborated) WITH COMPLETE SOLUTIONS

Nagelhout Pharm 2 Test 2 EXAM (2025) QUESTIONS AND
(elaborated) WITH COMPLETE SOLUTIONS




Enzymes for metabolism of catecholamines - (ANSWERS)COMT
MAO


Post synaptic neurotransmitter sympathetic - (ANSWERS)NE


Interference with synthesis of transmitter - (ANSWERS)sympatholytic -
choline acetyl transferase inhibitors


Metabolic transformation by same pathway as precursor of transmitter -
(ANSWERS)sympatholytic - methyldopa


Blockade of transport system at nerve terminal membrane -
(ANSWERS)sympathomimetic - cocaine


Blockade of transport system of storage vesicle -
(ANSWERS)sympatholytic - reserpine, vesamicol


Promotion of exocytosis or displacement of transmitter from axonal
terminal - (ANSWERS)sympathomimetic - amphetammine, tyramine



, Nagelhout Pharm 2 Test 2 EXAM (2025) QUESTIONS AND
(elaborated) WITH COMPLETE SOLUTIONS




Prevention of release of transmitter - (ANSWERS)sympatholytic -
botulinim toxin, clonidine, dexmedetomidine


Mimicry of transmitter at postjunctional sites -
(ANSWERS)sympathomimetic - dobutamine, terbutaline, albuterol,
isoproterenol, methacholine, bethanachol, nicotine,


Blockade of post synaptic receptor - (ANSWERS)sympatholytic - Atropine,
atracurium, -amines, -osin, -olol


Inhibition of enzymatic breakdown of transmitter -
(ANSWERS)sympathomimetic - MAO inhibitors, COMT inhibitors, ache
inhibitors


Interference with second messenger system -
(ANSWERS)sympathomimetic - milrinone


Choline acetyl transferase inhibitors - (ANSWERS)sympatholytic