NR 566 Final Exam Advanced Pharmacology
Questions & Answers | NP Study Guide
|100%Verified|Graded A+ and Updated
Raloxifene (Evista) and bisphosphonates (alendronate, calcitonin)
Correct Answer:
alternatives for hormone replacement therapy
Selective Estrogen Receptor Modulators (SERMs)
Correct Answer:
Tamoxifen, toremifene, raloxifene -- provide estrogen benefits while avoiding its drawbacks
Dysfunctional uterine bleeding
Correct Answer:
10-14 day course of progestin
Amenorrhea treatment
Correct Answer:
progestin helps induce menstrual flow
Amenorrhea estrogen levels are low
Correct Answer:
give progestin for 5-10 days
Long term progestin therapy
Correct Answer:
protection against endometrial cancer
Estradiol
Correct Answer:
most active estrogenic compound. oral estrogen option
,Advantages of estrogen transdermal patch
Correct Answer:
lower total estrogen dose. less n/v. less fluctuation of estrogen blood levels. lower r/f DVT, PE and stroke
Femring
Correct Answer:
intravaginal ring controls hot flashes and night sweats. Treats vulval and vaginal atrophy
No gap method of changing from one OC to another
Correct Answer:
go straight from one type of OC to the other without taking a gap.
initiating OC treatment
Correct Answer:
first day of menstrual cycle (no backup BC needed) OR first sunday after onset of menses (backup BC
needed for 7 days)
Initiating androgen therapy short term
Correct Answer:
delayed sexual maturation causing a boy significant distress. Limited course of Fluoxymesterone and
methyltestosterone are approved.
androgen therapy long term
Correct Answer:
if delayed puberty is the result of true hypogonadism
role of androgens in anemia
Correct Answer:
promote synthesis of erythropoietin the renal hormone that stimulates production of RBCs
Alprostadil preferred administration
Correct Answer:
direct injection into the corpus cavernosum. Rapid response
Finasteride
Correct Answer:
,BPH tx 5a reductase inhibitor. Causes prostate to shrink. benefits take months
Tamsulosin
Correct Answer:
BPH tx alpha adrenergic antagonist. relaxes smooth muscle. benefits are rapid
Adverse effects of silodosin and tamsulosin
Correct Answer:
r/f floppy iris syndrome during cataract surgery.
Chlamydia tx
Correct Answer:
azithromycin 1g PO x single dose. doxycycline 100mg PO BID 7 days
Gonococcal urethritis tx
Correct Answer:
ceftriaxone IM single dose 250mg-1g based on weight
Bacterial vaginosis tx
Correct Answer:
metronidazole 500mg PO 2x day for 7 days.
Herpes (HSV) tx
Correct Answer:
acyclovir 400mg TID 7-10 days, valacyclovir or famciclovir
Trichomoniasis tx
Correct Answer:
metronidazole 2g PO x1 dose or tinidazole
Syphilis
Correct Answer:
benzathine penicillin 2.4mil units IM
Mild symptoms PD tx
Correct Answer:
MAO-B inhibitor like rasagiline or selegiline
, Severe symptoms PD tx
Correct Answer:
levodopa + carbodopa or dopamine agonist
PD tx for improving motor function
Correct Answer:
levodopa
PD tx for drug induced dyskinesias
Correct Answer:
dopamine agonist
COMT inhibitor
Correct Answer:
Entacapone (Comtan). added to levo/carbidopa to increase levo concentrations & extend half life &
decrease wearing off time
Pramipexole side effects
Correct Answer:
impulse control disorders, combined with levodopa causes orthostatic hypotension and dyskinesias
Pregabalin
Correct Answer:
Safest medication for seizure patients on OC
Phenytoin
Correct Answer:
can decrease effects of OCs, warfarin and glucocorticoids
Migraine tx 1st line
Correct Answer:
serotonin 1b/1d receptor agonists (triptans)
First line migraine prevention
Correct Answer:
propanolol
Questions & Answers | NP Study Guide
|100%Verified|Graded A+ and Updated
Raloxifene (Evista) and bisphosphonates (alendronate, calcitonin)
Correct Answer:
alternatives for hormone replacement therapy
Selective Estrogen Receptor Modulators (SERMs)
Correct Answer:
Tamoxifen, toremifene, raloxifene -- provide estrogen benefits while avoiding its drawbacks
Dysfunctional uterine bleeding
Correct Answer:
10-14 day course of progestin
Amenorrhea treatment
Correct Answer:
progestin helps induce menstrual flow
Amenorrhea estrogen levels are low
Correct Answer:
give progestin for 5-10 days
Long term progestin therapy
Correct Answer:
protection against endometrial cancer
Estradiol
Correct Answer:
most active estrogenic compound. oral estrogen option
,Advantages of estrogen transdermal patch
Correct Answer:
lower total estrogen dose. less n/v. less fluctuation of estrogen blood levels. lower r/f DVT, PE and stroke
Femring
Correct Answer:
intravaginal ring controls hot flashes and night sweats. Treats vulval and vaginal atrophy
No gap method of changing from one OC to another
Correct Answer:
go straight from one type of OC to the other without taking a gap.
initiating OC treatment
Correct Answer:
first day of menstrual cycle (no backup BC needed) OR first sunday after onset of menses (backup BC
needed for 7 days)
Initiating androgen therapy short term
Correct Answer:
delayed sexual maturation causing a boy significant distress. Limited course of Fluoxymesterone and
methyltestosterone are approved.
androgen therapy long term
Correct Answer:
if delayed puberty is the result of true hypogonadism
role of androgens in anemia
Correct Answer:
promote synthesis of erythropoietin the renal hormone that stimulates production of RBCs
Alprostadil preferred administration
Correct Answer:
direct injection into the corpus cavernosum. Rapid response
Finasteride
Correct Answer:
,BPH tx 5a reductase inhibitor. Causes prostate to shrink. benefits take months
Tamsulosin
Correct Answer:
BPH tx alpha adrenergic antagonist. relaxes smooth muscle. benefits are rapid
Adverse effects of silodosin and tamsulosin
Correct Answer:
r/f floppy iris syndrome during cataract surgery.
Chlamydia tx
Correct Answer:
azithromycin 1g PO x single dose. doxycycline 100mg PO BID 7 days
Gonococcal urethritis tx
Correct Answer:
ceftriaxone IM single dose 250mg-1g based on weight
Bacterial vaginosis tx
Correct Answer:
metronidazole 500mg PO 2x day for 7 days.
Herpes (HSV) tx
Correct Answer:
acyclovir 400mg TID 7-10 days, valacyclovir or famciclovir
Trichomoniasis tx
Correct Answer:
metronidazole 2g PO x1 dose or tinidazole
Syphilis
Correct Answer:
benzathine penicillin 2.4mil units IM
Mild symptoms PD tx
Correct Answer:
MAO-B inhibitor like rasagiline or selegiline
, Severe symptoms PD tx
Correct Answer:
levodopa + carbodopa or dopamine agonist
PD tx for improving motor function
Correct Answer:
levodopa
PD tx for drug induced dyskinesias
Correct Answer:
dopamine agonist
COMT inhibitor
Correct Answer:
Entacapone (Comtan). added to levo/carbidopa to increase levo concentrations & extend half life &
decrease wearing off time
Pramipexole side effects
Correct Answer:
impulse control disorders, combined with levodopa causes orthostatic hypotension and dyskinesias
Pregabalin
Correct Answer:
Safest medication for seizure patients on OC
Phenytoin
Correct Answer:
can decrease effects of OCs, warfarin and glucocorticoids
Migraine tx 1st line
Correct Answer:
serotonin 1b/1d receptor agonists (triptans)
First line migraine prevention
Correct Answer:
propanolol
