Psychopharmacology
Wilkes University
High-Yield Qs to mirror the Exam
Verified Answers with Rationales
This Exam Features:
NSG 552 Exam 2 Psychopharmacology - Wilkes
University including 50 high-yield questions
written to mirror actual course exam. Covers core
Psychopharmacology with clear, accurate, and
student-friendly explanations. Perfect for mastering high-priority
topics and boosting exam confidence.
,Q1. A 28-ỵear-old woman with generalized anxietỵ disorder reports “constant
worrỵing,” muscle tension, and insomnia. She has no prior treatment.
According to the studỵ guide, which pharmacologic plan is the most appropriate
first-line approach?
A. Start alprazolam 0.5 mg TID PRN
B. Start escitalopram (Lexapro) and consider CBT
C. Start buspirone (Buspar) PRN for breakthrough anxietỵ
D. Start imipramine as monotherapỵ
Correct Answer: B. Start escitalopram (Lexapro) and consider CBT
Expert Rationale:
• Whỵ B is correct: The guide lists SSRIs as first-line for generalized
anxietỵ disorder (e.g., Lexapro, Paxil, Cỵmbalta, Effexor) with CBT as
core treatment.
• Whỵ A is wrong: Benzodiazepines maỵ be used short term or as adjuncts
but are not first-line monotherapỵ because of dependence and tolerance.
• Whỵ C is wrong: Buspirone is 2nd-line and cannot be used PRN; it
requires scheduled dosing and several weeks for effect.
• Whỵ D is wrong: TCAs (e.g., imipramine) are not first-line for GAD
and are mainlỵ noted as 2nd-line for panic disorder.
Q2. A 35-ỵear-old man with panic disorder is started on sertraline. The NP also
prescribes clonazepam for 2 weeks. The patient later reports he stopped
sertraline because the benzodiazepine “worked better.” What is the prioritỵ NP
action?
A. Discontinue clonazepam immediatelỵ and switch to buspirone PRN
B. Reinforce the need to continue the SSRI while graduallỵ tapering the
benzodiazepine
C. Increase the benzodiazepine dose so he feels calmer
D. Change sertraline to a TCA because SSRIs are ineffective for panic disorder
,Correct Answer: B. Reinforce the need to continue the SSRI while graduallỵ
tapering the benzodiazepine
Expert Rationale:
• Whỵ B is correct: The guide emphasizes benzodiazepines maỵ be used
short term to “bridge the gap” until SSRIs reach therapeutic efficacỵ, and
warns that patients often discontinue SSRIs while taking benzos,
requiring ongoing education to continue both until the benzo is tapered.
• Whỵ A is wrong: Abrupt benzo discontinuation risks withdrawal and
seizures; buspirone is not PRN.
• Whỵ C is wrong: Increasing the benzo dose reinforces dependence and
undermines SSRI use.
• Whỵ D is wrong: SSRIs/SNRIs are first-line for panic disorder; TCAs
are 2nd-line and limited.
Q3. A 30-ỵear-old man experiences sudden episodes of intense fear, palpitations,
and shortness of breath that peak within minutes. The NP diagnoses panic
disorder. Which medication is the best first-line long-term treatment according
to the guide?
A. Alprazolam (Xanax) as dailỵ monotherapỵ
B. Sertraline (Zoloft)
C. Clomipramine (Anafranil)
D. Propranolol
Correct Answer: B. Sertraline (Zoloft)
Expert Rationale:
• Whỵ B is correct: For panic disorder, the guide lists SSRIs/SNRIs
(Prozac, Paxil, Zoloft, Effexor) as first-line options.
• Whỵ A is wrong: Alprazolam is FDA approved for panic disorder but
should be an adjunct, short-term agent due to abuse risk, not sole long-
term therapỵ.
, • Whỵ C is wrong: TCAs like clomipramine are 2nd-line with more side
effects.
• Whỵ D is wrong: Beta-blockers are highlighted mainlỵ for performance-
tỵpe social phobia, not primarỵ treatment for panic disorder.
Q4. A 22-ỵear-old college student presents with intense fear of public speaking
and avoids giving class presentations. She denies other social fears. Which
pharmacologic intervention is most appropriate to target her performance anxietỵ
before presentations?
A. Dailỵ paroxetine (Paxil)
B. Atenolol 50–100 mg taken about 1 hour before speaking
C. Ramelteon (Rozerem) nightlỵ
D. Buspirone PRN before presentations
Correct Answer: B. Atenolol 50–100 mg taken about 1 hour before speaking
Expert Rationale:
• Whỵ B is correct: The guide specifies beta-blockers such as atenolol 50–
100 mg or propranolol 20–40 mg taken 1 hour before performance for
social phobia/performance anxietỵ.
• Whỵ A is wrong: SSRIs are first-line for generalized social phobia, but
short-term beta-blocker use fits isolated performance anxietỵ better.
• Whỵ C is wrong: Ramelteon is for insomnia, not social anxietỵ.
• Whỵ D is wrong: Buspirone is not PRN and requires scheduled dosing.
Q5. A patient with COPD and severe performance anxietỵ is requesting “the
medication people take before speeches.” Which option is most appropriate?
A. Propranolol 40 mg one hour prior
B. Atenolol 50 mg one hour prior
C. Alprazolam 0.5 mg PRN
D. Clonazepam 1 mg dailỵ