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Updated 2 Version Exam + Study Guide
True & False Questions
Multiple Choice Questions and Answers
Expert-Verified Explanations
Table of Contents
BIOD 331 MODULE 4 EXAM VERSION 1...............................................................................................2
BIOD 331 MODULE 4 EXAM VERSION 2.............................................................................................35
BIOD 331 MODULE 4 EXAM VERSION 1
### Question 1
The coagulation cascade involves each of the following except:
- Make thrombocytes
Verified Explanation:
The coagulation cascade is responsible for the conversion of soluble plasma
proteins into an insoluble fibrin clot. It includes activation of intrinsic and
extrinsic pathways, conversion of prothrombin to thrombin, and fibrinogen to
fibrin. Thrombocyte (platelet) formation is a process called thrombopoiesis,
primarily taking place in the bone marrow, and is not a direct function of the
coagulation cascade.
,---
Which of the following increases the chance of clotting? Select all that
apply.
- Protein C deficiency
Verified Explanation:
Protein C is a natural anticoagulant that degrades factors Va and VIIIa. Its
deficiency results in a loss of inhibitory control of the coagulation cascade,
thus increasing clotting risk. In contrast, vitamin K deficiency, vWF
deficiency, and thrombocytopenia impair coagulation and increase bleeding
risk.
---
The three stages of hemostasis include each of the following except:
- Vascular dilation
Verified Explanation:
Hemostasis refers to the cessation of bleeding and consists of: (1)
vascular constriction, (2) formation of a platelet plug, and (3) blood
coagulation. Vascular dilation is not a component of hemostasis and would,
in fact, promote rather than prevent bleeding.
---
### Question 2
Which of the following medications would decrease a person’s risk
for clotting? Select all that apply.
- Heparin
, - Warfarin
- Lovenox (enoxaparin)
Verified Explanation:
Heparin, warfarin, and Lovenox are anticoagulants that interfere with
different aspects of coagulation. Heparin and Lovenox (a low-molecular-
weight heparin) enhance antithrombin III activity, while warfarin inhibits
vitamin K-dependent synthesis of clotting factors. Vitamin K is needed for
clotting factor synthesis and could promote clotting if used in excess.
---
A deficiency in which of the following would lead to a
.hypercoagulable state? Select all that apply
- Protein C
- Protein S
- Antithrombin III
Verified Explanation:
Protein C, Protein S, and Antithrombin III are endogenous anticoagulants.
Deficiencies in these increase the risk for hypercoagulable states. Factors II,
VII, IX, X, and prothrombin deficiencies lead to bleeding disorders, not
clotting.
---
### Question 3
Which of the following is NOT a hypercoagulable state? Select all that
apply.
- Hemophilia A
Updated 2 Version Exam + Study Guide
True & False Questions
Multiple Choice Questions and Answers
Expert-Verified Explanations
Table of Contents
BIOD 331 MODULE 4 EXAM VERSION 1...............................................................................................2
BIOD 331 MODULE 4 EXAM VERSION 2.............................................................................................35
BIOD 331 MODULE 4 EXAM VERSION 1
### Question 1
The coagulation cascade involves each of the following except:
- Make thrombocytes
Verified Explanation:
The coagulation cascade is responsible for the conversion of soluble plasma
proteins into an insoluble fibrin clot. It includes activation of intrinsic and
extrinsic pathways, conversion of prothrombin to thrombin, and fibrinogen to
fibrin. Thrombocyte (platelet) formation is a process called thrombopoiesis,
primarily taking place in the bone marrow, and is not a direct function of the
coagulation cascade.
,---
Which of the following increases the chance of clotting? Select all that
apply.
- Protein C deficiency
Verified Explanation:
Protein C is a natural anticoagulant that degrades factors Va and VIIIa. Its
deficiency results in a loss of inhibitory control of the coagulation cascade,
thus increasing clotting risk. In contrast, vitamin K deficiency, vWF
deficiency, and thrombocytopenia impair coagulation and increase bleeding
risk.
---
The three stages of hemostasis include each of the following except:
- Vascular dilation
Verified Explanation:
Hemostasis refers to the cessation of bleeding and consists of: (1)
vascular constriction, (2) formation of a platelet plug, and (3) blood
coagulation. Vascular dilation is not a component of hemostasis and would,
in fact, promote rather than prevent bleeding.
---
### Question 2
Which of the following medications would decrease a person’s risk
for clotting? Select all that apply.
- Heparin
, - Warfarin
- Lovenox (enoxaparin)
Verified Explanation:
Heparin, warfarin, and Lovenox are anticoagulants that interfere with
different aspects of coagulation. Heparin and Lovenox (a low-molecular-
weight heparin) enhance antithrombin III activity, while warfarin inhibits
vitamin K-dependent synthesis of clotting factors. Vitamin K is needed for
clotting factor synthesis and could promote clotting if used in excess.
---
A deficiency in which of the following would lead to a
.hypercoagulable state? Select all that apply
- Protein C
- Protein S
- Antithrombin III
Verified Explanation:
Protein C, Protein S, and Antithrombin III are endogenous anticoagulants.
Deficiencies in these increase the risk for hypercoagulable states. Factors II,
VII, IX, X, and prothrombin deficiencies lead to bleeding disorders, not
clotting.
---
### Question 3
Which of the following is NOT a hypercoagulable state? Select all that
apply.
- Hemophilia A
