Ultra-High-Yield Hematology Board Exam Mastery: Anemias, Hemolysis, Leukemias, Coagulopathies, Platelet Disorders, RBC Morphology, Hemoglobinopathies, Transfusion Medicine, Clotting Factor Deficiencies, Peripheral Smear Diagnostics Questions Provided with

Ultra-High-Yield Hematology Board Exam Mastery: Anemias, Hemolysis, Leukemias, Coagulopathies, Platelet Disorders, RBC Morphology, Hemoglobinopathies, Transfusion Medicine, Clotting Factor Deficiencies, Peripheral Smear Diagnostics Questions Provided with A+ Graded Rationales Latest Updated 2026 What does high WBC and high PMNs tell you stress demargination (stress response - post trauma) What does a high WBC and 5% blasts tell you Leukemoid reaction, seen in burn pts or anyextreme stress (extreme demargination looks like leukemia), metamyelocytes -- myelocytes What does a high WBC and bands tell you Left shift - they have an infection What does a high WBC and 5% blasts tell you Leukemia What does a high WBC and B cells tell you Bacterial infection What diseases have a high eosinophils "NAACP" Neoplasm (lymphoma) Allergy/ Asthma Addison's disease (no cortisol → relative eosinophilia) Collagen vascular disease Parasites What diseases have high monocytes (15%) "STELS" Syphilis: chancre, rash, warts TB: hemoptysis, night sweats EBV: teenager sick for a month Listeria: baby who is sick Salmonella: food What do high reticulocytes (1%) tell you RBC is being destroyed peripherally What do low reticulocytes tell you Decrease production of bone marrow, not working right What is poikilocytosis RBCs of different shapes What is the RBC normal lifespan 120 days What is the RBC lifespan when there's a problem 60 to 90 days ( same time as the shelf life of Blood Bank units) What is the platelet lifespan 7 days What does "penia" tell you Low levels (usually due to virus or drugs) What does " cytosis" tell you High levels what does "cythemia" tell you High levels What is the difference between plasma and serum Plasma: no RBC Serum: no RBC or fibrinogen What are the microcytic hypochromic anemias Defect in hemoglobin synthesis ( RBC small and pale) "FAST lead": F- Fe deficiency A- anemia of chronic disease S- sideroblastic anemia T- Alpha and beta thalassemias L- lead poisoning What will you see with iron deficiency anemia increased TIBC, associated with menses, GI bleeding, and koilonychia What will you see with anemia of chronic disease decreased TIBC What will you see with sideroblastic anemia decreased d-ALA synthase; common with blood transfusions What will you see in beta-thalassemia Seen in Mediterraneans, chromosome 11 point mutation * Type of Allelic Heterogeneity* What will you see in lead poisoning Decreased dALA dehydrogenase, Decreased ferrochelatase, Blue lines on x-ray History of eating old paint chips What are the megaloblastic anemias vitamin B12 deficiency, folate deficiency, alcoholism What are some causes of vitamin B12 deficiency tapeworms, veganism, type A gastritis, pernicious anemia What are some causes of folate deficiency Diet, old food,