ECPI 2026 QUESTIONS WITH COMPLETE SOLUTIONS
Tricyclic and cyclic compounds
Selective serotonin reuptake inhibitors (SSRIs) most common
Monoamine oxidase inhibitors (MAOIs)
Other antidepressants
Antidepressants are divided into four groups:
Hypertensive Crisis
Major side effect of MAOIs?
Tyrosine/Tyramine
(MAO needed to breakdown tyrosine… no foods w/tyrosine -
most cheeses, aged meats (sausage, pepperoni), beans, avocado,
beer, tofu, soy products, sauerkraut, yogurt, sour cream,
peanuts, MSG…also can not be taken with other
antidepressants, anti-hypertensives, anesthesia, CNS
depressants)
What is MAO used to breakdown?
Sedation, Headaches
Side effects of Nefazodone and Trazodone? (Antidepressants)
Loss of appetite, Nausea, Agitation, Insomnia
Side effects of Bupropion and Venlafaxine?
Trazodone
What antidepressant causes a prolonged erection (Priapism)?
, MAOI + SSRI or other serotonin raising medications
What interaction of medications causes Serotonin Syndrome?
Agitation, insomnia, sweating, fever, tachycardia, hypertension,
rigidity, hyperreflexia, confusion, tremor/seizures.
Signs and symptoms of Serotonin Syndrome?
Coma and or Death
What can Serotonin Syndrome cause in severe/extreme cases?
First thing in the Morning
What time of the day do we give SSRI's?
At Night
What time of the day do we give Cyclic compounds?
Lithium, some anticonvulsants (carbamazepine, valproic acid;
gabapentin, topiramate, oxcarbazepine, and lamotrigine)
They Treat bipolar illness.
Mood-Stabilizing Drugs and what they treat? (BIPOLAR)
Normalizes reuptake of certain neurotransmitters
Mechanism of action for Lithium?
Increase levels of GABA
Mechanism of action for Valproic acid and topiramate?
Inhibit the kindling process
Mechanism of action for Valproic acid and carbamazepine?