ANATOMY NBME 2026 LATEST ACTUAL
EXAM QUESTIONS AND CORRECT
ANSWERS GRADED A+
55-year old man has had patchy leukoplakia of the anterior floor
of his mouth for 4 years. He now has a raised, firm white lesion in
the same area. Examination of tissue obtained on biopsy of this
new lesion is most likely to show:
A. Aphthous ulcer
B. Burkitts lymphoma
C. Candida infection
D. Kaposi's sarcoma
E. mixed tumor of the parotid gland
F. Squamous cell carcinoma
G. Warthin's tumor Correct Answer F. Squamous cell carcinoma
31 year old woman is admitted to the hospital in labor at 28 weeks
gestation. Administration of which of the following will most likely
enhance production of surfactant by fetal type II alveolar cells?
A. Corticosteroids
B. Glucagon
C. Growth hormone
,D. Insulin
E. Somatostatin Correct Answer A. Corticosteroids
A previously healthy 56-year old man has the sudden onset of
severe headaches that become worse in the afternoons. His
blood pressure is 180/110mmHg. Renal arteriography shows 85%
occlusion of the right renal artery. The laboratory finding that best
predicts whether an operation that relieves the obstruction will
reduce the blood pressure to normal is increased renin activity in
the
A. left renal artery vs right renal artery
B. left renal vein vs right renal vein
C right renal artery vs left renal artery
D. right renal vein vs left renal vein Correct Answer D. right renal
vein vs left renal vein
neonate has ambiguous genitalia. In the first 48 hours of life, the
neonate feeds poorly and becomes dehydrated. Which of the
following is the most likely diagnosis?
A. androgen insensitivity syndrome
B. 5alpha-reductase deficiency
C. 17- hydroxylase deficiency
D. 21- hydroxylase deficiency
E. true hermaphroditism Correct Answer D. 21- hydroxylase
deficiency
,4 year old girl is brought to the ED because of a 5-day history of
fever, diffuse abdominal pain, nausea, vomiting, and diarrhea.
Examination shows petechiae, hepatomegaly, and splenomegaly.
Hemoglobin concentration is 8.7g/dL and platelet count is
60,000/mm. Peripheral blood smear shows erythrocyte
fragmentation. Which of the following renal findings is most likely
to be associated with her condition?
A. Glomerular crescent formation
B. IgG-associated glomerular basement membrane antibody
C. Membranoproliferative glomerulonephritis
D. Narrowing of the capillary wall by fibrin deposition
E. Periglomerular granuloma with giant cells Correct Answer D.
Narrowing of the capillary wall by fibrin deposition
The developmental anomaly shown in this stillborn fetus is most
commonly characterized by which type of inheritance?
A. Autosomal dominant
B. Autosomal recessive
C. Mitochondrial
D. Multifactorial
E. Sex-linked Correct Answer D. Multifactorial
, 30-year old woman with type 1 diabetes melltius has increasing
vulvar pruritus and a vaginal discharge. A wet mount preparation
of the discharge is shown. Which of the following is the most likely
causal organism?
A. Candida albicans
B. Chlamydia trachomatis
C. Herpes simplex virus
D. Human papillomavirus
E. Trichomonasvaginalis Correct Answer A. Candida albicans
The presence of which of the following is characteristic of the
infectious agent of bovine spongiform encephalopathy?
A. RNA +, DNA +, Protein +
B. RNA +, DNA +, Protein -
C. RNA +, DNA -, Protein +
D. RNA +, DNA -, Protein -
E. RNA -, DNA +, Protein +
F. RNA -, DNA +, Protein -
G. RNA -, DNA -, Protein -
H. RNA -, DNA -, Protein + Correct Answer H. RNA -, DNA -,
Protein +
healthy 30-year old man is participating in a study of the effects of
a competitive inhibitor of endothelial nitric oxide synthase. After
EXAM QUESTIONS AND CORRECT
ANSWERS GRADED A+
55-year old man has had patchy leukoplakia of the anterior floor
of his mouth for 4 years. He now has a raised, firm white lesion in
the same area. Examination of tissue obtained on biopsy of this
new lesion is most likely to show:
A. Aphthous ulcer
B. Burkitts lymphoma
C. Candida infection
D. Kaposi's sarcoma
E. mixed tumor of the parotid gland
F. Squamous cell carcinoma
G. Warthin's tumor Correct Answer F. Squamous cell carcinoma
31 year old woman is admitted to the hospital in labor at 28 weeks
gestation. Administration of which of the following will most likely
enhance production of surfactant by fetal type II alveolar cells?
A. Corticosteroids
B. Glucagon
C. Growth hormone
,D. Insulin
E. Somatostatin Correct Answer A. Corticosteroids
A previously healthy 56-year old man has the sudden onset of
severe headaches that become worse in the afternoons. His
blood pressure is 180/110mmHg. Renal arteriography shows 85%
occlusion of the right renal artery. The laboratory finding that best
predicts whether an operation that relieves the obstruction will
reduce the blood pressure to normal is increased renin activity in
the
A. left renal artery vs right renal artery
B. left renal vein vs right renal vein
C right renal artery vs left renal artery
D. right renal vein vs left renal vein Correct Answer D. right renal
vein vs left renal vein
neonate has ambiguous genitalia. In the first 48 hours of life, the
neonate feeds poorly and becomes dehydrated. Which of the
following is the most likely diagnosis?
A. androgen insensitivity syndrome
B. 5alpha-reductase deficiency
C. 17- hydroxylase deficiency
D. 21- hydroxylase deficiency
E. true hermaphroditism Correct Answer D. 21- hydroxylase
deficiency
,4 year old girl is brought to the ED because of a 5-day history of
fever, diffuse abdominal pain, nausea, vomiting, and diarrhea.
Examination shows petechiae, hepatomegaly, and splenomegaly.
Hemoglobin concentration is 8.7g/dL and platelet count is
60,000/mm. Peripheral blood smear shows erythrocyte
fragmentation. Which of the following renal findings is most likely
to be associated with her condition?
A. Glomerular crescent formation
B. IgG-associated glomerular basement membrane antibody
C. Membranoproliferative glomerulonephritis
D. Narrowing of the capillary wall by fibrin deposition
E. Periglomerular granuloma with giant cells Correct Answer D.
Narrowing of the capillary wall by fibrin deposition
The developmental anomaly shown in this stillborn fetus is most
commonly characterized by which type of inheritance?
A. Autosomal dominant
B. Autosomal recessive
C. Mitochondrial
D. Multifactorial
E. Sex-linked Correct Answer D. Multifactorial
, 30-year old woman with type 1 diabetes melltius has increasing
vulvar pruritus and a vaginal discharge. A wet mount preparation
of the discharge is shown. Which of the following is the most likely
causal organism?
A. Candida albicans
B. Chlamydia trachomatis
C. Herpes simplex virus
D. Human papillomavirus
E. Trichomonasvaginalis Correct Answer A. Candida albicans
The presence of which of the following is characteristic of the
infectious agent of bovine spongiform encephalopathy?
A. RNA +, DNA +, Protein +
B. RNA +, DNA +, Protein -
C. RNA +, DNA -, Protein +
D. RNA +, DNA -, Protein -
E. RNA -, DNA +, Protein +
F. RNA -, DNA +, Protein -
G. RNA -, DNA -, Protein -
H. RNA -, DNA -, Protein + Correct Answer H. RNA -, DNA -,
Protein +
healthy 30-year old man is participating in a study of the effects of
a competitive inhibitor of endothelial nitric oxide synthase. After
