Nur 641 E Final Exam Advanced
Pathophysiology and
Pharmacology Study Guide /
Questions & Answers | Grade A |
100% Correct – Grand Canyon
University
Description
This NUR 641E Advanced Pathophysiology and Pharmacology final
exam at Grand Canyon University (GCU) is a comprehensive
assessment designed for nurse educators. It evaluates the
integration of disease processes with evidence-based
pharmacological treatments across the lifespan.
Exam Format & Scope
Structure: Primarily multiple-choice questions focusing on
application in real-world nursing practice.
Key Focus Areas: Interpreting symptoms of illness, identifying
cellular alterations, and determining safe medication and herbal
therapy utilization.
Prep Resource: A specific NUR-641E Final Exam Study Guide is
typically provided in Topic 7 to help students prepare.
High-Yield Study Topics
Pharmacology Fundamentals: Pharmacokinetics (ADME),
pharmacodynamics, drug half-life, and steady-state.
Systemic Pathophysiology:
Endocrine: Insulin's role in hyperkalemia treatment, Type 2 diabetes
resistance, and SIADH.
1
, Neurological: Multiple Sclerosis (demyelination) and Alzheimer's
disease.
Cardiovascular: Hypertension management (ACE inhibitors like
Captopril) and heart failure.
Respiratory: Cystic fibrosis, COPD, and asthma.
Immunology: Primary vs. secondary lines of defense and
inflammatory responses.
Electrolytes & Acid-Base: Regulation mechanisms, hyperkalemia,
and metabolic vs. respiratory acidosis/alkalosis.
Specific Clinical Pearls:
FDA labeling for ICU sedatives (e.g., Propofol or Dexmedetomidine).
Types of cellular necrosis (e.g., liquefactive vs. coagulative in wet
gangrene).
Beers Criteria for potentially inappropriate medication use in older
adults.
Quiz_________________?
absorption, distribution, metabolism, excretion -
Answer☑️
Pharmacokinetics involves
Quiz_________________?
absorption from the administration site either directly or indirectly
in the blood plasma -
Answer☑️
Pharmacokinetic absorption
2
, Quiz_________________?
reversibly or irreversibly move from the bloodstream into the
interstitial and intracellular fluid -
Answer☑️
pharmacokinetics distribution
Quiz_________________?
biotransformed via hepatic metabolism or by other tissue -
Answer☑️
Pharmacokinetics metabolism
Quiz_________________?
1. highest bioavailability
2. places entire does into venin thus bypassing absorption
3. avoids hepatic first pass metabolism in the liver -
Answer☑️
Intravenous medications
Quiz_________________?
3
, usually reached within 4-5 half lives of the drug -
Answer☑️
steady state medication
Quiz_________________?
1.the time required for the elimination process to reduce 2.the
concentration of the drug to one half what it was at initial
administration
3.determines drug frequency
4. predicts length of toxic effects
5. constant first order pharmacokinetics of a drug -
Answer☑️
drug half life
Quiz_________________?
drug is metabolized at a constant rate per unit -
Answer☑️
zero order (nonlinear)
Quiz_________________?
4
Pathophysiology and
Pharmacology Study Guide /
Questions & Answers | Grade A |
100% Correct – Grand Canyon
University
Description
This NUR 641E Advanced Pathophysiology and Pharmacology final
exam at Grand Canyon University (GCU) is a comprehensive
assessment designed for nurse educators. It evaluates the
integration of disease processes with evidence-based
pharmacological treatments across the lifespan.
Exam Format & Scope
Structure: Primarily multiple-choice questions focusing on
application in real-world nursing practice.
Key Focus Areas: Interpreting symptoms of illness, identifying
cellular alterations, and determining safe medication and herbal
therapy utilization.
Prep Resource: A specific NUR-641E Final Exam Study Guide is
typically provided in Topic 7 to help students prepare.
High-Yield Study Topics
Pharmacology Fundamentals: Pharmacokinetics (ADME),
pharmacodynamics, drug half-life, and steady-state.
Systemic Pathophysiology:
Endocrine: Insulin's role in hyperkalemia treatment, Type 2 diabetes
resistance, and SIADH.
1
, Neurological: Multiple Sclerosis (demyelination) and Alzheimer's
disease.
Cardiovascular: Hypertension management (ACE inhibitors like
Captopril) and heart failure.
Respiratory: Cystic fibrosis, COPD, and asthma.
Immunology: Primary vs. secondary lines of defense and
inflammatory responses.
Electrolytes & Acid-Base: Regulation mechanisms, hyperkalemia,
and metabolic vs. respiratory acidosis/alkalosis.
Specific Clinical Pearls:
FDA labeling for ICU sedatives (e.g., Propofol or Dexmedetomidine).
Types of cellular necrosis (e.g., liquefactive vs. coagulative in wet
gangrene).
Beers Criteria for potentially inappropriate medication use in older
adults.
Quiz_________________?
absorption, distribution, metabolism, excretion -
Answer☑️
Pharmacokinetics involves
Quiz_________________?
absorption from the administration site either directly or indirectly
in the blood plasma -
Answer☑️
Pharmacokinetic absorption
2
, Quiz_________________?
reversibly or irreversibly move from the bloodstream into the
interstitial and intracellular fluid -
Answer☑️
pharmacokinetics distribution
Quiz_________________?
biotransformed via hepatic metabolism or by other tissue -
Answer☑️
Pharmacokinetics metabolism
Quiz_________________?
1. highest bioavailability
2. places entire does into venin thus bypassing absorption
3. avoids hepatic first pass metabolism in the liver -
Answer☑️
Intravenous medications
Quiz_________________?
3
, usually reached within 4-5 half lives of the drug -
Answer☑️
steady state medication
Quiz_________________?
1.the time required for the elimination process to reduce 2.the
concentration of the drug to one half what it was at initial
administration
3.determines drug frequency
4. predicts length of toxic effects
5. constant first order pharmacokinetics of a drug -
Answer☑️
drug half life
Quiz_________________?
drug is metabolized at a constant rate per unit -
Answer☑️
zero order (nonlinear)
Quiz_________________?
4
