PRACTICE PAPER FOR 2026 SUMMER EXAMS
Oxford Cambridge and RSA
2025 Predicted Paper
A Level Biology A
H420/03 Unified biology
Time allowed: 1 hour 30 minutes
You can use:
• a scientific or graphical calculator
• a ruler (cm/mm)
* H
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 15 pages.
ADVICE
• Read each question carefully before you start your answer.
SOLE Property of Tyrion's
, PRACTICE PAPER FOR 2026 SUMMER EXAMS
Section A
1. (a) The diagram below shows a partial DNA sequence:
(i) Name the type of mutation if the sequence changes to 5' - ATG GGC TGA - 3'.
………………………………………………………………………………………………………………
…………………………………………………………………………………………………………...[1]
(ii) Explain how this mutation might affect the resulting protein.
………………………………………………………………………………………………………………
………………………………………………………………………………………………………………
………………………………………………………………………………………………………………
………………………………………………………………………………………………………………
………………………………………………………………………………………………………………
………………………………………………………………………….………………………………...[3]
Oxford Cambridge and RSA
2025 Predicted Paper
A Level Biology A
H420/03 Unified biology
Time allowed: 1 hour 30 minutes
You can use:
• a scientific or graphical calculator
• a ruler (cm/mm)
* H
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use
the lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might be
given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 70.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 15 pages.
ADVICE
• Read each question carefully before you start your answer.
SOLE Property of Tyrion's
, PRACTICE PAPER FOR 2026 SUMMER EXAMS
Section A
1. (a) The diagram below shows a partial DNA sequence:
(i) Name the type of mutation if the sequence changes to 5' - ATG GGC TGA - 3'.
………………………………………………………………………………………………………………
…………………………………………………………………………………………………………...[1]
(ii) Explain how this mutation might affect the resulting protein.
………………………………………………………………………………………………………………
………………………………………………………………………………………………………………
………………………………………………………………………………………………………………
………………………………………………………………………………………………………………
………………………………………………………………………………………………………………
………………………………………………………………………….………………………………...[3]
