TEST BANK For Basic and Clinical Pharmacology,
15th Edition by Bertram G. Katzung, Verified
Chapters 1 – 66
,1. A nurse working in radiology administers iodine to a patient who is
having a computed tomography (CT) scan. The nurse working on the
oncology unit administers chemotherapy to patients who have cancer. At
the Public Health Department, a nurse administers a measles-mumps-
rubella (MMR) vaccine toa 14-month-old child as a routine
immunization. Which branch of pharmacology best describes the actions
of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses
are involved with clinical pharmacology or pharmacotherapeutics,
which is a branch of pharmacology that deals with the uses of drugs to
treat, prevent, and diagnose disease. The radiology nurse is
administering a drug to help diagnose a disease. The oncology nurse is
administering a drug to help treat adisease. Pharmacoeconomics
includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body
andpharmacokinetics is how the body acts on the body.
2. When involved in phase III drug evaluation studies, what
responsibilitieswould the nurse have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate patients to be involved in the drug study
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of the drug
Ans: C
Feedback:
, Phase III studies involve use of a drug in a vast clinical population in
whichpatients are asked to record any symptoms they experience
while taking thedrugs. Nurses may be responsible for helping collect
and analyze the information to be shared with the Food and Drug
Administration (FDA) butwould not conduct research independently
because nurses do not prescribe medications. Use of animals in drug
testing is done in the preclinical trials. Select patients who are involved
in phase II studies to participate in studies where the participants have
the disease the drug is intended to treat. These patients are monitored
closely for drug action and adverse effects. Phase I studies involve
healthy human volunteers who are usually paid for their participation.
Nurses may observe for adverse effects and toxicity.
3. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident
victim.The nurse is aware this drug has a high abuse potential. Under
what categorywould morphine be classified?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs
because of severe dependence liability. Schedule I drugs have high
abuse potential and no accepted medical use. Schedule III drugs have a
lesser abuse potential than II and an accepted medical use. Schedule IV
drugs havelow abuse potential and limited dependence liability.
4. What concept is considered when generic drugs are substituted for
brandname drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the
, systemic circulation and is available to act on body cells. Binders used
in a generic drug may not be the same as those used in the brand name
drug. Therefore, the way the body breaks down and uses the drug may
differ, which may eliminate a generic drug substitution. Critical
concentration is the amount ofa drug that is needed to cause a
therapeutic effect and should not differ between generic and brand
name medications. Distribution is the phase of pharmacokinetics,
which involves the movement of a drug to the bodys tissues and is the
same in generic and brand name drugs. A drugs half-life isthe time it
takes for the amount of drug to decrease to half the peak level, which
should not change when substituting a generic medication.
5. A nurse is assessing the patients home medication use. After listening
to thepatient list current medications, the nurse asks what priority
question?
A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
C) Are these medications safe to take during pregnancy?
D) Do you take any over-the-counter medications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-
counter medications because patients may not consider them
important. The patient is unlikely to know the meaning of orphan drugs
unless they too are health care providers. Safety during pregnancy, use
of a generic medication, or classification of orphan drugs are things the
patient would be unable to answer but could be found in reference
books if the nurse wishes to researchthem.
6. After completing a course on pharmacology for nurses, what will the
nurseknow?
A) Everything necessary for safe and effective medication administration
B) Current pharmacologic therapy; the nurse will not require
ongoingeducation for 5 years.
C) General drug information; the nurse can consult a drug guide for
specificdrug information.
D) The drug actions that are associated with each
classification ofmedication
Ans: C
15th Edition by Bertram G. Katzung, Verified
Chapters 1 – 66
,1. A nurse working in radiology administers iodine to a patient who is
having a computed tomography (CT) scan. The nurse working on the
oncology unit administers chemotherapy to patients who have cancer. At
the Public Health Department, a nurse administers a measles-mumps-
rubella (MMR) vaccine toa 14-month-old child as a routine
immunization. Which branch of pharmacology best describes the actions
of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses
are involved with clinical pharmacology or pharmacotherapeutics,
which is a branch of pharmacology that deals with the uses of drugs to
treat, prevent, and diagnose disease. The radiology nurse is
administering a drug to help diagnose a disease. The oncology nurse is
administering a drug to help treat adisease. Pharmacoeconomics
includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body
andpharmacokinetics is how the body acts on the body.
2. When involved in phase III drug evaluation studies, what
responsibilitieswould the nurse have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate patients to be involved in the drug study
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of the drug
Ans: C
Feedback:
, Phase III studies involve use of a drug in a vast clinical population in
whichpatients are asked to record any symptoms they experience
while taking thedrugs. Nurses may be responsible for helping collect
and analyze the information to be shared with the Food and Drug
Administration (FDA) butwould not conduct research independently
because nurses do not prescribe medications. Use of animals in drug
testing is done in the preclinical trials. Select patients who are involved
in phase II studies to participate in studies where the participants have
the disease the drug is intended to treat. These patients are monitored
closely for drug action and adverse effects. Phase I studies involve
healthy human volunteers who are usually paid for their participation.
Nurses may observe for adverse effects and toxicity.
3. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident
victim.The nurse is aware this drug has a high abuse potential. Under
what categorywould morphine be classified?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs
because of severe dependence liability. Schedule I drugs have high
abuse potential and no accepted medical use. Schedule III drugs have a
lesser abuse potential than II and an accepted medical use. Schedule IV
drugs havelow abuse potential and limited dependence liability.
4. What concept is considered when generic drugs are substituted for
brandname drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the
, systemic circulation and is available to act on body cells. Binders used
in a generic drug may not be the same as those used in the brand name
drug. Therefore, the way the body breaks down and uses the drug may
differ, which may eliminate a generic drug substitution. Critical
concentration is the amount ofa drug that is needed to cause a
therapeutic effect and should not differ between generic and brand
name medications. Distribution is the phase of pharmacokinetics,
which involves the movement of a drug to the bodys tissues and is the
same in generic and brand name drugs. A drugs half-life isthe time it
takes for the amount of drug to decrease to half the peak level, which
should not change when substituting a generic medication.
5. A nurse is assessing the patients home medication use. After listening
to thepatient list current medications, the nurse asks what priority
question?
A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
C) Are these medications safe to take during pregnancy?
D) Do you take any over-the-counter medications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-
counter medications because patients may not consider them
important. The patient is unlikely to know the meaning of orphan drugs
unless they too are health care providers. Safety during pregnancy, use
of a generic medication, or classification of orphan drugs are things the
patient would be unable to answer but could be found in reference
books if the nurse wishes to researchthem.
6. After completing a course on pharmacology for nurses, what will the
nurseknow?
A) Everything necessary for safe and effective medication administration
B) Current pharmacologic therapy; the nurse will not require
ongoingeducation for 5 years.
C) General drug information; the nurse can consult a drug guide for
specificdrug information.
D) The drug actions that are associated with each
classification ofmedication
Ans: C
