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Biochemistry | Questions & Answers
| Grade A | 100% Correct - Portage
Learning
Metabolic processing of urea and the synthesis of ATP
Question:
What is the ETC?
Answer:
the chain of e- created from NADH and FADH2 being oxidized at the enzyme
complexes
Question:
What is a unique feature about the enzyme complexes?
Answer:
they are highly regulated
,Question:
Where does majority of the oxidative phosphorylation reactions occur in the
mitochondria?
Answer:
in the matrix
Question:
How many phases in oxidative phosphorylation? what complexes are
associated with each phase and what is the general jobs of each phase?
Answer:
3 phases
phase 1: complex 1 and 2- where NADH and FADH2 were oxidized
phase 2: complex 3 and 4- where the H+ get pumped out
Phase 3: where H+ flows in through the ATP synthase to make ATP
Question:
What are the reactions in phase 1
Answer:
complex 1: NADH + H+ + CoQ yields NAD+ + CoQH2
complex 2: FADH2 + CoQ yields FAD+ + CoQH2
, Question:
How does complex 1 differ from complex 2?
Answer:
complex 1 is more complex as it is 40 polypeptides long. it also pumps H+ out
of the membrane, but this does not occur at complex 2.
Complex 2 uses succinate as a coenzyme to form fumarate
Question:
What happens to the structure of NADH and FADH2 when the H+ are
removed?
Answer:
the H is removed from the N on the rings- this causes a double bond to form
when removed and a charge on nitrogen
Question:
What happen at the complexes of phase 2?
Answer:
complex 3: receives the Hs from CoQ. It pumps out the protons and electrons
are shuttled o complex 4 via protein cytochrome C (4 Cy-c for each e-)
complex 4: water is formed via reaction:
O2 + 4H+ + 4e- yields 2 H2O