PLTW Medical Interventions Unit 2.2 Review Exam Questions Answered Correctly Latest Update 2026/2027

PLTW Medical Interventions Unit 2.2 Review Exam Questions Answered Correctly Latest Update 2026/2027 Plasmid - Answers - Gene of any size - No cell specificity - No immune response - Does not integrate into the host genome - Less efficient at entering cells Liposome - Answers - Gene of any size - No cell specificity - No immune response - Does not integrate into the host genome - Less efficient at entering cells Herpes Virus - Answers - Gene up to 20,000bp - Nervous system cells - Immune response - Does not integrate into genome - Less efficient at entering cells Adeno-Associated Virus - Answers - Gene up to 5,000bp - No cell specificity - No immune response - Integrate into genome - Efficient at entering cells Adeno Virus - Answers - Gene up to 7,500bp - No cell specificity - Immune response - Does not integrate into genome - Efficient at entering cells Retro Virus - Answers - Gene up to 8,000bp - Only diving cells - Immune response - Integrates into genome randomly - Less efficient at entering cells Lenti Virus - Answers - Gene up to 8,500bp - No cell specificity - No immune response - Integrates into genome randomly - Efficient at entering cells Invivo - Answers - Inside patient - Pros: Benefits occur more rapidly - Cons: Greater chance of immune response, vector may enter unselected cell, cannot be analyzed to see results Exvivo - Answers - Outside of patient - Pros: Less likely to cause immune response, can ensure cell selection and ensure results of therapy - Cons: Patient has to wait for benefits of therapy Concerns of Gene Therapy - Answers - Immune response - Selected cells - Function of vector How is the new gene transferred into the hosts cells? - Answers There are two different ways that the DNA can be integrated into the cells. When using a virus as a vector, they will attach to the outside of the cell (as they usually do) but will release the modified DNA that will code for the correct protein in the cell. As for the use of other vectors, plasmids would be taken up and integrated by surrounding cells (through pili) What does CRISPR stand for? - Answers Clustered Regularly Interspaced Short Palindromic Repeats