Introduction to Behavioral Neuroscience
OpenStax
Chapter 14: Psychopharmacology
Multiple Choice
1. What does the term “bioavailability” refer to in pharmacology?
A. The amount of drug that reaches the circulatory system*
B. The concentration of a drug
C. The amount of drug that is excreted from the body
D. The physiological or behavioral response to the drug
Bloom’s Level 1. Remembering
2. The primary route of drug excretion is
A. Saliva
B. Sweat
C. Urine*
D. Feces
Bloom’s Level 1. Remembering
3. What is unique about a biased agonist compared to a full agonist?
A. It has a higher binding affinity to the receptor
B. It activates only a subset of intracellular signaling pathways associated with the
receptor*
C. It has a longer half-life
D. It produces the opposite effect of a full agonist
Bloom’s Level 2. Understanding
4. Which of the following influences receptor activity by binding outside of the orthosteric
site?
A. Inverse agonist
B. Biased agonist
C. Allosteric modulator*
D. Partial agonist
Bloom’s Level 1. Remembering
5. Which three brain regions are the primary components of the mesocorticolimbic pathway?
A. Amygdala, hippocampus, ventral tegmental area
B. Prefrontal cortex, hippocampus, nucleus accumbens
C. Ventral tegmental area, nucleus accumbens, prefrontal cortex*
D. Hippocampus, nucleus accumbens, amygdala
1
, Introduction to Behavioral Neuroscience
OpenStax
Bloom’s Level 1. Remembering
6. Which brain region is most associated with self-control, decision making, and emotional
regulation?
A. Prefrontal cortex*
B. Hypothalamus
C. Lateral habenula
D. Ventral tegmental area
Bloom’s Level 1. Remembering
7. How does nicotine produce its reinforcing effects?
A. By inhibiting the reuptake of neurotransmitters
B. By blocking the action of adenosine receptors
C. By activating NMDA receptors
D. By activating nicotinic acetylcholine receptors*
Bloom’s Level 1. Remembering
8. Which of the following best describes tolerance?
A. The process by which a drug is eliminated from the body
B. A biochemical reaction that can occur when two or more drugs are taken together
C. The blood-brain barrier’s ability to resist infiltration of certain drugs
D. Reduced response to a drug over time*
Bloom’s Level 2. Understanding
9. Which component of the intravenous self-administration experimental technique bests
models relapse behavior in humans?
A. Breakpoint
B. Reinstatement*
C. Progressive Ratio
D. Extinction
Bloom’s Level 2. Understanding
10. In a progressive-ratio schedule, the number of responses at which the animal stops working
for a drug is called
A. Breakpoint*
B. Stop point
C. Quit point
D. Intoxication point
Bloom’s Level 1. Remembering
2
OpenStax
Chapter 14: Psychopharmacology
Multiple Choice
1. What does the term “bioavailability” refer to in pharmacology?
A. The amount of drug that reaches the circulatory system*
B. The concentration of a drug
C. The amount of drug that is excreted from the body
D. The physiological or behavioral response to the drug
Bloom’s Level 1. Remembering
2. The primary route of drug excretion is
A. Saliva
B. Sweat
C. Urine*
D. Feces
Bloom’s Level 1. Remembering
3. What is unique about a biased agonist compared to a full agonist?
A. It has a higher binding affinity to the receptor
B. It activates only a subset of intracellular signaling pathways associated with the
receptor*
C. It has a longer half-life
D. It produces the opposite effect of a full agonist
Bloom’s Level 2. Understanding
4. Which of the following influences receptor activity by binding outside of the orthosteric
site?
A. Inverse agonist
B. Biased agonist
C. Allosteric modulator*
D. Partial agonist
Bloom’s Level 1. Remembering
5. Which three brain regions are the primary components of the mesocorticolimbic pathway?
A. Amygdala, hippocampus, ventral tegmental area
B. Prefrontal cortex, hippocampus, nucleus accumbens
C. Ventral tegmental area, nucleus accumbens, prefrontal cortex*
D. Hippocampus, nucleus accumbens, amygdala
1
, Introduction to Behavioral Neuroscience
OpenStax
Bloom’s Level 1. Remembering
6. Which brain region is most associated with self-control, decision making, and emotional
regulation?
A. Prefrontal cortex*
B. Hypothalamus
C. Lateral habenula
D. Ventral tegmental area
Bloom’s Level 1. Remembering
7. How does nicotine produce its reinforcing effects?
A. By inhibiting the reuptake of neurotransmitters
B. By blocking the action of adenosine receptors
C. By activating NMDA receptors
D. By activating nicotinic acetylcholine receptors*
Bloom’s Level 1. Remembering
8. Which of the following best describes tolerance?
A. The process by which a drug is eliminated from the body
B. A biochemical reaction that can occur when two or more drugs are taken together
C. The blood-brain barrier’s ability to resist infiltration of certain drugs
D. Reduced response to a drug over time*
Bloom’s Level 2. Understanding
9. Which component of the intravenous self-administration experimental technique bests
models relapse behavior in humans?
A. Breakpoint
B. Reinstatement*
C. Progressive Ratio
D. Extinction
Bloom’s Level 2. Understanding
10. In a progressive-ratio schedule, the number of responses at which the animal stops working
for a drug is called
A. Breakpoint*
B. Stop point
C. Quit point
D. Intoxication point
Bloom’s Level 1. Remembering
2
