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FORPATHOPHYSIOLOGY 2NDEDITION
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BY CAPRIOTTI
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, Chapter 1, The Cell in Health and Illness
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Multiple Choice
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Identify the choice that best completes the statement or answers the question.
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1. Which statement regarding the sodium–potassium pump is correct?
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1. The cell’s plasma membrane is more soluble to sodium ions than potassium ions.
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2. The concentration of sodium ions should be higher inside the cell compartment.
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3. The concentration of potassium ions should be higher outside the
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cell compartment.
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4. The active transport involves pumping out three sodium ions and pumping in
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two potassium ions.
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2. In the absence of oxygen, which cellular function creates the same amount of energy as is created
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fg in the presence of oxygen?
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1. Dissipation of pyruvic acid fg fg fg
2. Initiation of the citric acid cycle fg fg fg fg fg
3. Activation of acetyl-coenzyme A fg fg fg
4. Creation of acidosis via lactic acid fg fg fg fg fg
3. How many adenosine triphosphates (ATPs) are produced in aerobic energy metabolism?
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1. 2 f g f g
2. 3 f g f g
3. 34 f g f g
4. 53 f g f g
4. Which cell organelles differ in their number according to the cell’s energy needs?
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1. Ribosomes
2. Mitochondria
3. Ribonucleic acids fg
4. Deoxyribonucleic acids fg
5. Which option best supports the reason more energy is produced when a person is exercising?
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1. Exercise causes an increase in the synthesis of protein. fg fg fg fg fg fg fg fg
2. There is an increase in the production of pyruvic acid in the cells.
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3. The conversion of pyruvic acid to lactic acid is increased by exercise.
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4. Muscle cells have more mitochondria to meet energy demands.
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6. When does ribosomal protein synthesis cease?
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1. During endoplasmic reticulum stress fg fg fg
2. During the synthesis of adenosine triphosphate (ATP) fg fg fg fg fg fg
3. During a severe hypoxic state fg fg fg fg
4. During the processing of prohormone fg fg fg fg
7. Which cellular organelles are responsible for propelling mucus and inhaled debris out of the lungs?
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1. Cilia
2. Microfilaments
3. Secretory vesicles fg
, 4. Endoplasmic reticula fg
f g 8. Which are the key proteins in the contractile units of the muscle cells?
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1. Actin and myosin fg fg
2. Prohormone and tubulin fg fg
3. Tubulin and actin fg fg
4. Myosin and prohormone fg fg
f g 9. f g Which deficiency causes Tay–Sachs disease?
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1. Proteasome
2. Peroxisome
3. Macrophage
4. Lysosomal enzymes fg
10. Which is a characteristic of adrenoleukodystrophy?
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1. Accumulation of ganglioside fg fg
2. Cessation of ribosomal protein synthesis fg fg fg fg
3. Acceleration of cellular proteasome activity fg fg fg fg
4. Accumulation of long-chain fatty acids in the nervous system fg fg fg fg fg fg fg fg
11. Which statement regarding endoplasmic reticulum (ER) stress is correct?
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1. During ER stress, proteins are rapidly degraded.fg fg fg fg fg fg
2. During ER stress, lipids cannot travel to their proper intracellular locations.
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3. During ER stress, long-chain fatty acids accumulate in the nervous system.
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4. DuringER stress, nondeNg Ur a Rd eSdI sT
taB
nc.eC
fg s Oa c cumulateinthecesll.
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12. A client is diagnosed with type 1 diabetes mellitus. At a cellular level, which function is likely
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to be involved?
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1. Inability of ribosomes to produce a specific type of protein
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2. Incorrect processing of a protein by the Golgi apparatus
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3. Stagnation of a previously dynamic action in microtubules fg fg fg fg fg fg fg
4. Obstruction of the smooth endoplasmic reticulum fg fg fg fg fg
13. A newborn patient exhibits characteristics of severe physical deformities. Which cellular
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component is examined to determine the cause and probability of the disease being
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genetically transferred?
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1. Transfer RNA fg
2. Ribosomal RNA fg
3. Double helix of DNA fg fg fg
4. Mitochondrial DNA fg
14. A hiker experiences muscle pain and acidosis while ascending a mountain during a long,
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steep climb. Which is the reason for these manifestations?
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1. Cellular hypoxia fg
2. Autolysis
3. Heterolysis
4. Cellular edema fg
15. Which factor provides DNA the unique molecular ability to replicate?
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1. The pairing of nitrogenous basesfg fg fg fg
, 2. The presence of pyrimidine bases
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3. The presence of nucleotides fg fg fg
4. The nitrogenous base and phosphate bond
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16. How f g many nitrogenous bases compose a single codon?
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1. f g 2
f g
2. f g 3
f g
3. f g 4
f g
4. f g 5
f g
17. Which components form the structure of DNA?
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1. Nucleotides
2. Amino acids fg
3. Fatty acids fg
4. Phosphates
18. Which factor is essential in order for protein synthesis to occur?
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1. Free-standing ribosomes within the cell fg fg fg fg
2. Protein blueprint from the cell of the DNA fg fg fg fg fg fg fg
3. Specific information from the nucleus of the cell fg fg fg fg fg fg fg
4. Transfer RNA to move the protein out of the cell fg fg fg fg fg fg fg fg fg
19. Tetracycline antibiotic is prescribed for an adult client with chlamydia infection. Which is
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the mechanism of action of the drug?
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1. It prevents the replicatio
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2. It alters the configuration of bacterial cytoplasm.
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3. It interferes with the function of bacterial ribosomes.
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4. It inhibits the functions of bacterial mitochondria.
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20. Where does the conversion of a prohormone into a hormone take place?
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1. In the ribosomes fg fg
2. In the Golgi apparatus fg fg fg
3. In the secretory granules fg fg fg
4. In the endoplasmic reticulum fg fg fg
21. Which is the cell’s “master mind”?
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1. Nucleus
2. Ribosome
3. Golgi apparatus fg
4. Endoplasmic reticulum fg
Multiple Response
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Identify one or more choices that best complete the statement or answer the question.
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22. Which statements regarding the microtubules are true? Select all that apply.
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1. Microtubules are solid. fg fg
2. Microtubules are flexible. fg fg
3. Microtubules are composed of tubulin. fg fg fg fg